Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Conserved virulence factor B-like winged helix
Restriction system protein Mrr-like N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Ribosomal protein uS12 methylthiotransferase RimO
Outer membrane protein beta-barrel domain-containing protein
TonB-dependent receptor-like beta-barrel
Ribonucleotide reductase large subunit C-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
UDP N-acetylglucosamine O-acyltransferase C-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
TonB-dependent receptor plug domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
NADPH-dependent 7-cyano-7-deazaguanine reductase
UDP-N-acetylenolpyruvoylglucosamine reductase
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Right-handed parallel beta-helix repeat-containing protein
Glycosyltransferase subfamily 4-like N-terminal
DNA protection during starvation protein
DNA-directed RNA polymerase subunit beta
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phenylalanine--tRNA ligase alpha subunit
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Phosphomannose isomerase type I catalytic
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Proton acceptor; for glutaminase activity
Peptidase M3A/M3B catalytic domain-containing protein
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Chromosomal replication initiator protein DnaA
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Release factor glutamine methyltransferase N-terminal
Outer membrane lipoprotein carrier protein LolA
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Organic solvent tolerance-like N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gliding motility protein SprA N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
NAD(P) transhydrogenase alpha subunit C-terminal
RNA polymerase sigma factor 70 region 4 type 2
ATP-dependent Clp protease ATP-binding subunit ClpX
3-beta hydroxysteroid dehydrogenase/isomerase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ATP-dependent DNA helicase RecG C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Penicillin-binding protein transpeptidase
Sodium/calcium exchanger membrane region
SUF system FeS cluster assembly SufBD N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucosamine/galactosamine-6-phosphate isomerase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Fimbrial subunit protein C-terminal domain-containing protein
Impairs cleavage by lipoprotein signal peptidase and subsequent processing steps.
Important for oligomerization and fimbrium assembly
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Saccharopine dehydrogenase-like C-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Aminoacyl-transfer RNA synthetases class-II family profile
Pyruvate phosphate dikinase AMP/ATP-binding
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Alanyl-transfer RNA synthetases family profile
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA 2-O ribose methyltransferase substrate binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Ribose-phosphate pyrophosphokinase N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Polyribonucleotide nucleotidyltransferase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Polymerase/histidinol phosphatase N-terminal
Major facilitator superfamily (MFS) profile
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Polysaccharide biosynthesis protein C-terminal
T9SS C-terminal target domain-containing protein
DNA-directed DNA polymerase family A palm
5-glutamyl coenzyme A thioester intermediate
Plays an important role in substrate specificity
Shikimate dehydrogenase substrate binding N-terminal
Drastically decreased but still significant activities against Asp/Glu substrates, as well as detectable activity against substrates harboring hydrophobic residues at the P1 position.
Is essential for the Asp/Glu P1 specificity of DPP11; involved in the recognition of the Asp/Glu residue at the P1 position of substrate peptides
Significant increase (or preservation) of the catalytic activity.
The Asp/Glu preference is inverted, i.e., peptidase activity toward Leu-Asp-MCA nearly disappears, whereas that to Leu-Glu-MCA partially remains.
Secretion system C-terminal sorting domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Probable dual-specificity RNA methyltransferase RlmN
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Thiamine pyrophosphate enzyme TPP-binding
NIF system FeS cluster assembly NifU C-terminal
Probable nicotinate-nucleotide adenylyltransferase
Schiff-base intermediate with substrate; via pyruvic acid
Polysaccharide chain length determinant N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Carbamoyl-phosphate synthase small subunit N-terminal
Aspartate carbamoyltransferase regulatory chain
Exonuclease VII large subunit C-terminal
RNA binding; important for wobble base 34 recognition
Pyrroline-5-carboxylate reductase catalytic N-terminal
Crossover junction endodeoxyribonuclease RuvC
Glycoside hydrolase family 57 N-terminal
Ribosomal RNA small subunit methyltransferase A
DNA-directed RNA polymerase subunit beta'
Holliday junction branch migration complex subunit RuvA
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-deoxy-manno-octulosonate cytidylyltransferase
Pyruvate/ketoisovalerate oxidoreductase catalytic
N-acetylmuramic acid 6-phosphate etherase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Peptidase S9 prolyl oligopeptidase catalytic
Type I restriction enzyme R protein N-terminal
Schiff-base intermediate with dihydroxyacetone-P
UDP-3-O-acylglucosamine N-acyltransferase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
3-methyl-2-oxobutanoate hydroxymethyltransferase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Bacterial surface antigen (D15) domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Translation elongation factor P/YeiP central
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Small ribosomal subunit biogenesis GTPase RsgA
Redox-sensing transcriptional repressor Rex
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
TtsA-like Glycoside hydrolase family 108
Lipocalin-like domain-containing protein
tRNA pseudouridylate synthase B C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Putative membrane protein insertion efficiency factor
Gly-cisPro motif, important for rejection of L-amino acids
Solute-binding protein family 3/N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large-conductance mechanosensitive channel
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Ribosomal RNA large subunit methyltransferase H
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
SsuA/THI5-like domain-containing protein
Ribosomal RNA small subunit methyltransferase H
Meso-diaminopimelate D-dehydrogenase C-terminal
Phosphatidylglycerol lysyltransferase C-terminal