TonB system biopolymer transport component
Outer membrane protein beta-barrel domain-containing protein
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Endonuclease/exonuclease/phosphatase domain-containing protein
Aspartate/homoserine dehydrogenase NAD-binding
Interacts with tRNA; defines subfamily-specific binding signature
RND efflux pump membrane fusion protein barrel-sandwich
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
TonB-dependent receptor-like beta-barrel
Transcription factor NikR nickel binding C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alginate export domain-containing protein
N-end rule aminoacyl transferase C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Ribosomal RNA small subunit methyltransferase A
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
Interaction with polymerase core subunit RpoC
6-phosphogluconate dehydrogenase C-terminal
Major facilitator superfamily (MFS) profile
CobB/CobQ-like glutamine amidotransferase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Flagellar motor switch protein FliN-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Fatty acid synthase subunit PfaD N-terminal
Zinc-regulated TonB-dependent outer membrane receptor
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Gly-cisPro motif, important for rejection of L-amino acids
Cytochrome c-type biogenesis protein CcmF C-terminal
Bifunctional purine biosynthesis protein PurH
Peptidase S9 prolyl oligopeptidase catalytic
Sodium/calcium exchanger membrane region
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Formate-dependent nitrite reductase complex subunit
Tryptophan synthase beta chain-like PALP
Ion-translocating oxidoreductase complex subunit D
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cytochrome P460 domain-containing protein
DNA-directed RNA polymerase subunit beta'
Bacterial virulence factor lipase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Glycosyl transferase family 3 N-terminal
Schiff-base intermediate with acetaldehyde
Transglycosylase SLT domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit D
Cell wall-active antibiotics response LiaF-like C-terminal
Imidazole glycerol phosphate synthase subunit HisH
ATP-dependent protease ATPase subunit HslU
NarX-like N-terminal domain-containing protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase
Cyclic pyranopterin monophosphate synthase
Important for autoinhibition of adenylyltransferase activity
Flagellar basal body rod protein N-terminal
Ribosomal RNA large subunit methyltransferase E
Membrane fusion protein biotin-lipoyl like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aldehyde ferredoxin oxidoreductase N-terminal
Carboxy-S-adenosyl-L-methionine synthase
DNA-directed RNA polymerase subunit omega
Sec-independent protein translocase protein TatB
Putative phosphoenolpyruvate synthase regulatory protein
Cytochrome b561 bacterial/Ni-hydrogenase
High frequency lysogenization protein HflD homolog
Phenylalanine--tRNA ligase alpha subunit
Probable nicotinate-nucleotide adenylyltransferase
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Inosine/uridine-preferring nucleoside hydrolase
Transition state stabilizer; via amide nitrogen
Important for substrate binding and specificity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Ribosomal RNA large subunit methyltransferase G
Major facilitator superfamily associated
Reversibly protonated during proton transport
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
tRNA N6-adenosine threonylcarbamoyltransferase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
RNA methyltransferase SpoU/TrmH type C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Chalcone isomerase domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Signal recognition particle SRP54 helical bundle
Sulfatase-modifying factor enzyme domain-containing protein
Ribosomal RNA small subunit methyltransferase J
Transcription elongation factor GreA/GreB C-terminal
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Ribosomal RNA large subunit methyltransferase H
Glycosyl transferase family 28 C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Putative ATP-dependent zinc protease domain-containing protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
ATP-dependent Clp protease ATP-binding subunit ClpX
Cytochrome c-552/4 domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Polymerase/histidinol phosphatase N-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Flagellar basal-body/hook protein C-terminal
Release factor glutamine methyltransferase N-terminal
Outer membrane protein assembly factor BamC
Flagellar Assembly Protein A N-terminal region
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Solute-binding protein family 3/N-terminal
Type II secretion system protein GspG C-terminal
A-kinase anchor protein 7-like phosphoesterase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
YbaK/aminoacyl-tRNA synthetase-associated
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
DNA polymerase III subunit delta C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar hook-length control protein-like C-terminal
Cell division topological specificity factor
3,4-dihydroxy-2-butanone 4-phosphate synthase
Ion-translocating oxidoreductase complex subunit A
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Sulfite reductase [NADPH] hemoprotein beta-component
Disulphide bond isomerase DsbC/G N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Outer membrane protein assembly factor BamA
Intracellular proteinase inhibitor BsuPI
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
3-phosphoshikimate 1-carboxyvinyltransferase
Ysc84 actin-binding domain-containing protein
Tetrahaem cytochrome domain-containing protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Beta-lactamase-related domain-containing protein
3-isopropylmalate dehydratase small subunit
Sodium symporter small subunit predicted
Ribosomal RNA large subunit methyltransferase F
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Probable peptidoglycan glycosyltransferase FtsW
Endolytic peptidoglycan transglycosylase RlpA
Oxygen-dependent coproporphyrinogen-III oxidase
Sec-independent protein translocase protein TatA
Cob(I)alamin adenosyltransferase N-terminal
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Deoxyguanosinetriphosphate triphosphohydrolase-like protein
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Flagellar assembly protein FliH/Type III secretion system HrpE
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
5-glutamyl coenzyme A thioester intermediate
Quercetin 2,3-dioxygenase C-terminal cupin
Solute-binding protein family 3/N-terminal domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptide methionine sulphoxide reductase MsrA
ABC transporter substrate-binding protein PnrA-like
DNA replication/recombination mediator RecO N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Chaperone for general secretion pathway YbaY
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
O-(3'-phospho-DNA)-tyrosine intermediate
RNA polymerase sigma factor 70 region 4 type 2
Holliday junction branch migration complex subunit RuvB
Prepilin type IV endopeptidase peptidase
Glycine-zipper-containing OmpA-like membrane
Glycine-zipper-containing OmpA-like membrane domain-containing protein
Subtilisin-like protease fibronectin type-III
2-dehydro-3-deoxyphosphooctonate aldolase
Chromosomal replication initiator protein DnaA
Ribosomal RNA small subunit methyltransferase C
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
Appears to be important in orienting the phosphate for catalysis
Transcription elongation factor GreA/GreB N-terminal
Urease accessory protein UreH-like transmembrane
Important for beta-aspartyl-AMP intermediate formation
UDP-N-acetylenolpyruvoylglucosamine reductase
Involved in Mg(2+) ion dislocation from EF-Tu
Bacterial transcription activator effector binding
N-succinylglutamate 5-semialdehyde dehydrogenase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Biopterin-dependent aromatic amino acid hydroxylase family profile
Phosphoethanolamine transferase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Ion-translocating oxidoreductase complex subunit B
Bifunctional polymyxin resistance protein ArnA
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Type II secretion system protein GspC N-terminal
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Thiol:disulfide interchange protein DsbD
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Cation-transporting P-type ATPase N-terminal
nitrite reductase (cytochrome; ammonia-forming)
tRNA/tmRNA (uracil-C(5))-methyltransferase
3-methyl-2-oxobutanoate hydroxymethyltransferase
Helix-hairpin-helix DNA-binding motif class 1
Important for interaction with partner proteins
Imidazole glycerol phosphate synthase subunit HisF
Polysaccharide chain length determinant N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
PhoD-like phosphatase metallophosphatase
Phosphocysteine intermediate; for EIIB activity
Phosphoribosylformylglycinamidine cyclo-ligase
Membrane-bound lytic murein transglycosylase F
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
ATP-dependent Clp protease proteolytic subunit
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Dual-specificity RNA methyltransferase RlmN
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ribosomal RNA large subunit methyltransferase M
Heavy metal binding domain-containing protein
Succinate--CoA ligase [ADP-forming] subunit beta
Fatty acid oxidation complex subunit alpha
For 3-hydroxyacyl-CoA dehydrogenase activity
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
UDP N-acetylglucosamine O-acyltransferase C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Involved in allosteric activation by GTP
Protein-L-isoaspartate O-methyltransferase 2
Inner membrane protein YgaP-like transmembrane
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Protein-L-isoaspartate O-methyltransferase 1
Outer-membrane lipoprotein carrier protein
Ribosomal RNA large subunit methyltransferase K/L
3-isopropylmalate dehydratase large subunit
Threonine/serine exporter-like N-terminal
Transcription antitermination protein NusB
Alpha-D-phosphohexomutase alpha/beta/alpha
Bacterial type II secretion system protein E
ABC-type glycine betaine transport system substrate-binding
Lytic transglycosylase superhelical linker
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Cytochrome c-552/DMSO reductase-like haem-binding
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
FMN-dependent NADH:quinone oxidoreductase
Beta-lactamase hydrolase-like protein phosphatase-like
Beta-lactamase hydrolase-like protein phosphatase-like domain-containing protein
Sugar fermentation stimulation protein homolog
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Signal transduction histidine kinase internal region
Anthranilate synthase component I N-terminal
RNA binding; important for wobble base 34 recognition
Probable septum site-determining protein MinC
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Mechanosensitive ion channel inner membrane
3-beta hydroxysteroid dehydrogenase/isomerase
Holliday junction branch migration complex subunit RuvA
6-hydroxymethylpterin diphosphokinase MptE-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ATP-dependent Clp protease adapter protein ClpS
Pyruvate dehydrogenase E1 component middle
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Acyl-CoA dehydrogenase C-terminal bacterial-type
N-acetyl-gamma-glutamyl-phosphate reductase
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Plays an important role in substrate specificity
Ribosomal RNA small subunit methyltransferase G
Bacterial surface antigen (D15) domain-containing protein
Non-canonical purine NTP phosphatase/PRRC1
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
S-adenosylmethionine-dependent methyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
DNA-directed RNA polymerase subunit beta
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Heme-copper oxidase subunit III family profile
Periplasmic nitrate reductase, electron transfer subunit
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA1(Val) (adenine(37)-N6)-methyltransferase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Glucosamine/galactosamine-6-phosphate isomerase
Crossover junction endodeoxyribonuclease RuvC
Peptidase M43 pregnancy-associated plasma-A
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
Glutamate-1-semialdehyde 2,1-aminomutase
Leucyl/phenylalanyl-tRNA--protein transferase
Outer membrane protein assembly factor BamB
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Phosphotransferase system enzyme I N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyruvate phosphate dikinase AMP/ATP-binding
Glycine zipper domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Nucleoside-specific channel-forming protein, Tsx
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Putative beta-barrel assembly-enhancing protease
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Ribosomal RNA small subunit methyltransferase F
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Bacterial OB-fold domain-containing protein
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
Na+/H+ antiporter MnhB subunit-related protein
Gamma-butyrobetaine hydroxylase-like N-terminal
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Outer membrane protein assembly factor BamE
UDP-3-O-acyl-N-acetylglucosamine deacetylase
YcgL domain-containing protein Ssed_2518
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase
RapA2 cadherin-like domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Conserved virulence factor B-like winged helix
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Plays an important role in discriminating NADH against NADPH
Putative adhesin domain-containing protein
Small-conductance mechanosensitive channel
RNA 2-O ribose methyltransferase substrate binding
Aconitase A/isopropylmalate dehydratase small subunit swivel