Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
TATA box binding protein associated factor (TAF) histone-like fold
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
O-phospho-L-seryl-tRNA:Cys-tRNA synthase
Polymerase/histidinol phosphatase N-terminal
tRNA (cytidine(56)-2'-O)-methyltransferase
tRNA (pseudouridine(54)-N(1))-methyltransferase
Glycosyltransferase subfamily 4-like N-terminal
RNA 3'-terminal phosphate cyclase insert
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Probable transposase IS891/IS1136/IS1341
Na+/H+ antiporter MnhB subunit-related protein
Cation-transporting P-type ATPase N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Carbamoyl-phosphate synthase small subunit N-terminal
Formylmethanofuran dehydrogenase subunit E
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Plays an important role in substrate specificity
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Probable translation initiation factor IF-2
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glutamate-1-semialdehyde 2,1-aminomutase
60S ribosome subunit biogenesis protein NIP7 pre-PUA
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Bacterial type II secretion system protein E
Transcription factor CBF/NF-Y/archaeal histone
Non-canonical purine NTP phosphatase/PRRC1
Thiamine pyrophosphate enzyme TPP-binding
Dihydroneopterin aldolase MtpD C-terminal
Polysaccharide biosynthesis protein C-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Removed in mature form; by autocatalysis
Molybdopterin cofactor biosynthesis C (MoaC)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Dinitrogenase iron-molybdenum cofactor biosynthesis
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Signal recognition particle 19 kDa protein
Tetrahydromethanopterin S-methyltransferase subunit A
Digeranylgeranylglycerophospholipid reductase
Translation initiation factor 2 subunit gamma
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Schiff-base intermediate with substrate; via pyruvic acid
Imidazole glycerol phosphate synthase subunit HisF
Uncharacterized solute-binding protein Maeo_1470
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polysaccharide biosynthesis protein CapD-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
ATP-dependent dethiobiotin synthetase BioD
Extracellular matrix-binding protein ebh GA module
Translation initiation factor 2 subunit beta
Nicotinamide-nucleotide adenylyltransferase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
Probable cobalamin biosynthesis protein CobD
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Glutamate synthase alpha subunit C-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Tetrahydromethanopterin S-methyltransferase subunit H
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Tetrahydromethanopterin S-methyltransferase subunit B
GMP synthase [glutamine-hydrolyzing] subunit A
tRNA nucleotidyltransferase substrate binding
Ribosomal RNA large subunit methyltransferase E
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
Probable ribosomal RNA small subunit methyltransferase A
Aminoacyl-transfer RNA synthetases class-II family profile
Nascent polypeptide-associated complex protein
4-hydroxy-tetrahydrodipicolinate reductase
Phosphoribosylformylglycinamidine synthase subunit PurL
Probable L-tyrosine/L-aspartate decarboxylase
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Pyridoxal 5'-phosphate synthase subunit PdxT
Aconitase A/isopropylmalate dehydratase small subunit swivel
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Glycerol-1-phosphate dehydrogenase [NAD(P)+]
DNA-directed RNA polymerase subunit Rpo5
DNA-directed RNA polymerase subunit Rpo1C
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
3-phosphoshikimate 1-carboxyvinyltransferase
Cytochrome C biogenesis protein transmembrane
Methenyltetrahydromethanopterin cyclohydrolase
tRNA (guanine(26)-N(2))-dimethyltransferase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aspartate/homoserine dehydrogenase NAD-binding
Hypoxanthine/guanine phosphoribosyltransferase
Sodium/calcium exchanger membrane region
Tryptophan synthase beta chain-like PALP
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Alpha-D-phosphohexomutase alpha/beta/alpha
(5-formylfuran-3-yl)methyl phosphate synthase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Digeranylgeranylglyceryl phosphate synthase
Pyrroline-5-carboxylate reductase catalytic N-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
F420-dependent methylenetetrahydromethanopterin dehydrogenase
F420-non-reducing hydrogenase iron-sulfur subunit D
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Major facilitator superfamily (MFS) profile
Tetrahydromethanopterin S-methyltransferase F subunit
Pyruvate phosphate dikinase AMP/ATP-binding
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Glyceraldehyde-3-phosphate dehydrogenase
Thymidylate synthase/dCMP hydroxymethylase
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
N-(5'-phosphoribosyl)anthranilate isomerase
Geranylgeranylglyceryl phosphate synthase
SAM-dependent methyltransferase TRM5/TYW2-type
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cobalt-precorrin-5B C(1)-methyltransferase
Ribose-phosphate pyrophosphokinase N-terminal
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase
N-acetyl-gamma-glutamyl-phosphate reductase
Damage-control phosphatase ARMT1-like metal-binding
4-hydroxy-tetrahydrodipicolinate synthase
Glycosyl transferase family 28 C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Signal recognition particle 54 kDa protein
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Tetrahydromethanopterin S-methyltransferase subunit E
Small zinc finger protein HVO-2753-like zinc-binding pocket
Putative cytidyltransferase-related C-terminal region
Pseudouridine synthase I TruA alpha/beta
DNA-directed RNA polymerase RBP11-like dimerisation
Peptidase A24A-predicted C-terminal archaea
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein uL15/eL18
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Putative 8-amino-7-oxononanoate synthase