Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
TRAP C4-dicarboxylate transport system permease DctM subunit
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
O-(3'-phospho-DNA)-tyrosine intermediate
Lysidine-tRNA(Ile) synthetase C-terminal
Polysaccharide chain length determinant N-terminal
NIF system FeS cluster assembly NifU N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
TonB-dependent receptor-like beta-barrel
Polysaccharide biosynthesis protein CapD-like
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Important for autoinhibition of adenylyltransferase activity
Flagellar assembly protein FliH/Type III secretion system HrpE
Outer membrane protein beta-barrel domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
Bacteriophage tail tape measure C-terminal
Bacteriophage tail tape measure N-terminal
PEP-CTERM protein-sorting domain-containing protein
TonB-dependent receptor-like beta-barrel domain-containing protein
Major facilitator superfamily associated
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Flavocytochrome c sulphide dehydrogenase flavin-binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Interaction with polymerase core subunit RpoC
Tripartite tricarboxylate transporter substrate binding protein
Ribulose bisphosphate carboxylase small subunit
Glucose-methanol-choline oxidoreductase N-terminal
Sodium symporter small subunit predicted
Tryptophan synthase beta chain-like PALP
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Tetrahydrodipicolinate-N-succinyltransferase chain A
Flagellar hook-length control protein-like C-terminal
ABC transporter substrate-binding protein PnrA-like
Required for zinc-mediated homotetramerization and catalytic activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Major facilitator superfamily (MFS) profile
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Plays an important role in substrate specificity
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
RNA binding; important for wobble base 34 recognition
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
RND efflux pump membrane fusion protein barrel-sandwich
Pseudouridine synthase I TruA alpha/beta
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein uL2 C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sporulation stage II protein D amidase enhancer LytB N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Flagellar motor switch protein FliN-like C-terminal
Cob(I)alamin adenosyltransferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Membrane fusion protein biotin-lipoyl like
Nitrite/Sulfite reductase ferredoxin-like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL15/eL18
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cysteine sulfenic acid (-SOH) intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Transcription elongation factor GreA/GreB C-terminal
Periplasmic nitrate reductase, electron transfer subunit
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Alanyl-transfer RNA synthetases family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
N,N-dimethylformamidase beta subunit-like C-terminal
PhoD-like phosphatase metallophosphatase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Hydrazine synthase alpha subunit middle domain-containing protein
Solute-binding protein family 3/N-terminal domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribosomal RNA adenine methylase transferase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
5-glutamyl coenzyme A thioester intermediate
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Gly-cisPro motif, important for rejection of L-amino acids
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
O-(5'-phospho-DNA)-tyrosine intermediate
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Endoribonuclease L-PSP/chorismate mutase-like
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Gp5/Type VI secretion system Vgr protein OB-fold
RNA polymerase sigma factor 70 region 4 type 2
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
SGNH hydrolase-type esterase domain-containing protein
Ricin B lectin domain-containing protein
NADH-rubredoxin oxidoreductase C-terminal
Glycosyl transferase family 3 N-terminal
Urease accessory protein UreH-like transmembrane
Urease accessory protein UreH-like transmembrane domain-containing protein
Transcription elongation factor GreA/GreB N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Superoxide dismutase copper/zinc binding
Ribonucleotide reductase large subunit C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptidoglycan recognition protein family
NAD(P) transhydrogenase alpha subunit C-terminal
Insecticide toxin TcdB middle/N-terminal
Insecticide toxin TcdB middle/N-terminal domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Bacterial OB-fold domain-containing protein
Type I restriction modification DNA specificity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyridoxamine 5'-phosphate oxidase putative
Disulphide bond isomerase DsbC/G N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Outer-membrane lipoprotein carrier protein
DnaJ homologue subfamily C member 28 conserved
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Survival protein SurE-like phosphatase/nucleotidase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Membrane fusion protein (MFP) family protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Phosphotransferase system enzyme I N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Beta/gamma crystallin 'Greek key' domain-containing protein
Penicillin-binding protein transpeptidase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
PHA accumulation regulator DNA-binding N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Heme-copper oxidase subunit III family profile
Guanylate kinase/L-type calcium channel beta subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
Small ribosomal subunit protein uS4 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Virulence factor membrane-bound polymerase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prepilin type IV endopeptidase peptidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Polysaccharide biosynthesis protein C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Outer membrane protein assembly factor BamE
UDP N-acetylglucosamine O-acyltransferase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Prokaryotic-type class I peptide chain release factors
Release factor glutamine methyltransferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Translation elongation factor P/YeiP central
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyruvate/ketoisovalerate oxidoreductase catalytic
Shikimate dehydrogenase substrate binding N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Important for interaction with partner proteins
Subtilisin-like protease fibronectin type-III
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
YbaK/aminoacyl-tRNA synthetase-associated
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Haem-binding uptake Tiki superfamily ChaN
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Outer membrane beta-barrel domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Thiopeptide-type bacteriocin biosynthesis
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Proton acceptor; for glutaminase activity
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Saccharopine dehydrogenase-like C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Putative type VI secretion system Rhs element associated Vgr
Putative regulatory protein FmdB Zinc ribbon
Ribose-phosphate pyrophosphokinase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Carboxypeptidase regulatory-like domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Transposase IS204/IS1001/IS1096/IS1165 DDE
ABC transporter substrate-binding protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Chromosomal replication initiator DnaA C-terminal
General stress protein FMN-binding split barrel
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Anthranilate synthase component I N-terminal
6-phosphogluconate dehydrogenase NADP-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Type II secretion system protein GspC N-terminal domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Chalcone isomerase domain-containing protein
Pyruvate dehydrogenase E1 component middle
Bacterial bifunctional deaminase-reductase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Schiff-base intermediate with dihydroxyacetone-P
Gamma-butyrobetaine hydroxylase-like N-terminal
DNA replication/recombination mediator RecO N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Chromosomal replication initiator protein DnaA
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Reversibly protonated during proton transport