Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Resolvase/invertase-type recombinase catalytic
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
O-(5'-phospho-DNA)-tyrosine intermediate
Molybdopterin cofactor biosynthesis C (MoaC)
Terminase large subunit-like endonuclease
Ribose-phosphate pyrophosphokinase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Meso-diaminopimelate D-dehydrogenase C-terminal
Transcription regulator AsnC/Lrp ligand binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Bacterial type II secretion system protein E
ABC-type uncharacterised transport system
Helix-turn-helix conjugative transposon-like
Gram-positive cocci surface proteins LPxTG
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Polysaccharide biosynthesis protein C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyltransferase family 28 N-terminal
Positions MEP for the nucleophilic attack
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ABC-type glycine betaine transport system substrate-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pseudouridine synthase I TruA alpha/beta
Inosine monophosphate cyclohydrolase-like
Periplasmic binding protein domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Polymerase/histidinol phosphatase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Proton acceptor; for glutaminase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Alanyl-transfer RNA synthetases family profile
TRAP C4-dicarboxylate transport system permease DctM subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Major facilitator superfamily (MFS) profile
Aspartate/homoserine dehydrogenase NAD-binding
ATP-dependent DNA helicase RecG C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
FAD-dependent oxidoreductase 2 FAD binding
Superoxide dismutase copper/zinc binding
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Could play a key role in the communication between the regulatory and the substrate sites
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Conserved hypothetical protein CHP02679 N terminus
Essential for prephenate dehydratase activity
Probable transposase IS891/IS1136/IS1341
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
ABC transporter substrate-binding protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
SsuA/THI5-like domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Anthranilate synthase component I N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Phosphoribosylformylglycinamidine synthase linker
Gly-cisPro motif, important for rejection of L-amino acids
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Phosphocysteine intermediate; for EIIB activity
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Putative aromatic acid exporter C-terminal
Chromosomal replication initiator DnaA C-terminal
Putative auto-transporter adhesin head GIN
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
tRNA pseudouridylate synthase B C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
S-adenosylmethionine-dependent methyltransferase
Glycosyltransferase subfamily 4-like N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycoside hydrolase family 42 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Sporulation initiation factor Spo0A C-terminal
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 4
DNA mismatch repair proteins mutS family
Gamma-glutamylcyclotransferase AIG2-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Penicillin-binding protein transpeptidase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Cell envelope-related transcriptional attenuator
Release factor glutamine methyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycosyl transferase family 3 N-terminal
Tryptophan synthase beta chain-like PALP
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Lantibiotic biosynthesis protein dehydration
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
CobB/CobQ-like glutamine amidotransferase
Membrane insertase YidC/Oxa/ALB C-terminal
DNA-directed DNA polymerase family A palm
Alpha-D-phosphohexomutase alpha/beta/alpha
Thiamin pyrophosphokinase thiamin-binding
Cation-transporting P-type ATPase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Transcriptional coactivator p15 (PC4) C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gram-positive pilin backbone subunit 2 Cna-B-like
Dipicolinate synthase subunit A N-terminal
Schiff-base intermediate with acetaldehyde
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Interaction with polymerase core subunit RpoC
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Translation elongation factor P/YeiP central
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein bL9 C-terminal
Glycoside hydrolase family 31 N-terminal
Cell surface protein Shp haem-binding domain-containing protein
Stage III sporulation protein AA AAA+ ATPase
Threonine/serine exporter-like N-terminal
Type VII secretion system protein EssD-like
Type VII secretion system protein EssD-like domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polysaccharide biosynthesis protein CapD-like
Phosphotransferase system enzyme I N-terminal
High-affinity heme uptake system protein IsdE
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Sporulation transcription regulator WhiA N-terminal
Peptidase C39-like domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
DNA polymerase III delta subunit C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Prepilin type IV endopeptidase peptidase
AB hydrolase-1 domain-containing protein
Schiff-base intermediate with D-ribose 5-phosphate
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Polysaccharide chain length determinant N-terminal
Prokaryotic-type class I peptide chain release factors
Choloylglycine hydrolase/NAAA C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL15/eL18
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
serine-type D-Ala-D-Ala carboxypeptidase
Carbamoyl-phosphate synthase small subunit N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Sporulation stage IV protein A C-terminal
Reversibly protonated during proton transport
Phosphatidylglycerol lysyltransferase C-terminal
NIF system FeS cluster assembly NifU N-terminal
Glycoside hydrolase family 33 N-terminal
ABC transporter substrate-binding protein PnrA-like