Peptidase M1 membrane alanine aminopeptidase
RNA polymerase sigma factor 70 region 4 type 2
Alpha-D-phosphohexomutase alpha/beta/alpha
SUF system FeS cluster assembly SufBD N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Aminoacyl-transfer RNA synthetases class-II family profile
O-(5'-phospho-DNA)-tyrosine intermediate
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Transcriptional regulator LacI/GalR-like sensor
NADH:ubiquinone oxidoreductase 30kDa subunit
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Major facilitator superfamily (MFS) profile
Polymerase/histidinol phosphatase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RNA 2-O ribose methyltransferase substrate binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Translation elongation factor P/YeiP central
Cytochrome b/b6 N-terminal region profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Cytochrome C biogenesis protein transmembrane
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Exonuclease VII large subunit C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Tryptophan synthase beta chain-like PALP
Pyrroline-5-carboxylate reductase catalytic N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
4'-phosphopantetheinyl transferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Aconitase A/isopropylmalate dehydratase small subunit swivel
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Alpha-glycerophosphate oxidase C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Microcin J25-processing protein McjB C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl hydrolase-like 10 domain-containing protein
Plays an important role in substrate specificity
Beta-hexosaminidase bacterial type N-terminal
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Could be important to modulate the pK values of the two catalytic cysteine residues
NIF system FeS cluster assembly NifU N-terminal
Pyruvate dehydrogenase E1 component middle
Shikimate dehydrogenase substrate binding N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glycoside hydrolase family 42 N-terminal
Erythromycin biosynthesis protein CIII-like central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Prokaryotic-type class I peptide chain release factors
Solute-binding protein family 3/N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycoside hydrolase family 31 N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Penicillin-binding protein transpeptidase
Glycine cleavage T-protein C-terminal barrel
6-phosphogluconate dehydrogenase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphomannose isomerase type I catalytic
Adaptive response protein AidB N-terminal
DNA primase/polymerase bifunctional N-terminal
Phosphoribosylformylglycinamidine synthase linker
Pyrroline-5-carboxylate reductase dimerisation
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein uL6 alpha-beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transition state stabilizer; via amide nitrogen
Electron transfer via tryptophanyl radical
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
CobB/CobQ-like glutamine amidotransferase
Molybdopterin cofactor biosynthesis C (MoaC)
Glycosyltransferase subfamily 4-like N-terminal
Histidine-specific methyltransferase SAM-dependent
Proton acceptor; for glutaminase activity
Peptidoglycan recognition protein family
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Carbamoyl-phosphate synthase small subunit N-terminal
Alanyl-transfer RNA synthetases family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ABC transporter substrate-binding protein PnrA-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycoside-hydrolase family GH114 TIM-barrel
Mycothiol-dependent maleylpyruvate isomerase metal-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cell envelope-related transcriptional attenuator
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
DNA-directed DNA polymerase family A palm
Myo-inositol-1-phosphate synthase GAPDH-like
Peptide methionine sulphoxide reductase MsrA
Thiopeptide-type bacteriocin biosynthesis
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL15/eL18
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Heme-copper oxidase subunit III family profile
Pyrimidine nucleoside phosphorylase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
non-reducing end alpha-L-arabinofuranosidase
YbaK/aminoacyl-tRNA synthetase-associated
Essential for prephenate dehydratase activity
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Anthranilate synthase component I N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Nitrite/Sulfite reductase ferredoxin-like
Methylguanine DNA methyltransferase ribonuclease-like
Gp5/Type VI secretion system Vgr protein OB-fold
N-acetylneuraminic acid synthase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Putative glycogen debranching enzyme N-terminal
Gamma-glutamylcyclotransferase AIG2-like
NADH-rubredoxin oxidoreductase C-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Removed in mature form; by autocatalysis
Siderophore-interacting protein C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Bacterial type II secretion system protein E
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Reversibly protonated during proton transport
Involved in ionization of N3 of dUMP, leading to its activation
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cation-transporting P-type ATPase N-terminal
Signal recognition particle SRP54 helical bundle
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Acyltransferase MbtK/IucB-like conserved
Glycosyl transferase family 3 N-terminal
Sporulation transcription regulator WhiA N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Involved in allosteric activation by GTP
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ABC-type glycine betaine transport system substrate-binding
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Small ribosomal subunit protein uS4 N-terminal
Protein O-mannosyl-transferase C-terminal four TM
Ribosomal RNA adenine methylase transferase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Positions MEP for the nucleophilic attack
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Methionyl-tRNA synthetase anticodon-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA replication/recombination mediator RecO N-terminal