Major facilitator superfamily (MFS) profile
RND efflux pump membrane fusion protein barrel-sandwich
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Transcription antitermination protein NusB
Organic solvent tolerance-like N-terminal
Translation elongation factor P/YeiP central
RNA polymerase sigma factor 70 region 4 type 2
Bacterial type II secretion system protein E
Cysteine sulfenic acid (-SOH) intermediate
Urease accessory protein UreH-like transmembrane
Aminoacyl-transfer RNA synthetases class-II family profile
Glycine-zipper-containing OmpA-like membrane
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Resolvase/invertase-type recombinase catalytic
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Nitrite/Sulfite reductase ferredoxin-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Probable glycine dehydrogenase (decarboxylating) subunit 1
Prokaryotic-type class I peptide chain release factors
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit
UDP N-acetylglucosamine O-acyltransferase C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Heme-copper oxidase subunit III family profile
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Flagella basal body P-ring formation protein FlgA
Polymerase/histidinol phosphatase N-terminal
Polysaccharide chain length determinant N-terminal
DNA-directed DNA polymerase family A palm
Thiamine pyrophosphate enzyme TPP-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Flagellar motor switch protein FliN-like C-terminal
RlpA-like protein double-psi beta-barrel
Ribosomal RNA large subunit methyltransferase H
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tryptophan synthase beta chain-like PALP
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Helix-hairpin-helix DNA-binding motif class 1
Antitoxin Xre/MbcA/ParS-like toxin-binding
Tellurite resistance methyltransferase TehB-like
4-hydroxy-tetrahydrodipicolinate synthase
O-(3'-phospho-DNA)-tyrosine intermediate
Type II secretion system protein GspG C-terminal
Penicillin-binding protein transpeptidase
Important for interaction with partner proteins
nitrite reductase (cytochrome; ammonia-forming)
Polysaccharide biosynthesis protein C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glycine zipper 2TM domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Potassium-transporting ATPase potassium-binding subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Ysc84 actin-binding domain-containing protein
Reversibly protonated during proton transport
Flagellar assembly protein FliH/Type III secretion system HrpE
Ribosomal protein uS12 methylthiotransferase RimO
Important for beta-aspartyl-AMP intermediate formation
Probable transcriptional regulatory protein Gbem_3313
Chromosomal replication initiator protein DnaA
Glycosyltransferase subfamily 4-like N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Interaction with polymerase core subunit RpoC
TonB-dependent receptor-like beta-barrel
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycoside hydrolase family 42 N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Phosphoadenosine phosphosulphate reductase
Phosphoribosylformylglycinamidine synthase linker
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Sodium symporter small subunit predicted
Involved in ionization of N3 of dUMP, leading to its activation
Putative oxidoreductase/dehydrogenase Rossmann-like
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Mandelate racemase/muconate lactonizing enzyme N-terminal
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Ribose-phosphate pyrophosphokinase N-terminal
Phenylalanine--tRNA ligase alpha subunit
Schiff-base intermediate with substrate; via pyruvic acid
RNA binding; important for wobble base 34 recognition
Putative regulatory protein FmdB Zinc ribbon
NIF system FeS cluster assembly NifU C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Fibritin C-terminal domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Glutamyl-tRNA(Gln) amidotransferase subunit A
Polyribonucleotide nucleotidyltransferase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA 3'-terminal phosphate cyclase insert
Exosortase system-associated protein, TIGR04073 family
Putative Flp pilus-assembly TadG-like N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Involved in tetramerization or stability of the tetramer
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Sugar fermentation stimulation protein homolog
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Outer membrane protein beta-barrel domain-containing protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
4-hydroxy-tetrahydrodipicolinate reductase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
O-(phosphoribosyl dephospho-coenzyme A)serine
3-phosphoshikimate 1-carboxyvinyltransferase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
O-(5'-phospho-DNA)-tyrosine intermediate
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Membrane iron-sulfur containing protein FtrD-like
Pyrimidine/purine nucleoside phosphorylase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Gp5/Type VI secretion system Vgr protein OB-fold
Acetylserotonin O-methyltransferase dimerisation
Probable nicotinate-nucleotide adenylyltransferase
Glycine cleavage T-protein C-terminal barrel
Pyruvate/ketoisovalerate oxidoreductase catalytic
Na+/H+ antiporter MnhB subunit-related protein
Saccharopine dehydrogenase-like C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Essential for prephenate dehydratase activity
ATP-dependent Clp protease ATP-binding subunit ClpX
Pectate lyase superfamily protein domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Anthranilate synthase component I N-terminal
3-keto-disaccharide hydrolase domain-containing protein
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
NADH:ubiquinone oxidoreductase 30kDa subunit
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Plays an important role in substrate specificity
Prepilin type IV endopeptidase peptidase
Outer membrane lipoprotein-sorting protein
DNA-directed RNA polymerase subunit beta
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
NADH:ubiquinone oxidoreductase chain 4 N-terminal
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
Disulphide bond isomerase DsbC/G N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Type II secretion system protein GspE N-terminal
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Alpha-D-phosphohexomutase alpha/beta/alpha
Water stress and hypersensitive response
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Cation-transporting P-type ATPase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar hook-length control protein-like C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Holliday junction branch migration complex subunit RuvB
Cobalt-precorrin-5B C(1)-methyltransferase
Lysidine-tRNA(Ile) synthetase C-terminal
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Histidine-specific methyltransferase SAM-dependent
Polysaccharide biosynthesis protein CapD-like
DNA-directed RNA polymerase subunit omega
Phosphatidic acid phosphatase type 2/haloperoxidase
Chromosomal replication initiator DnaA C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Iron dependent repressor metal binding and dimerisation
Pyrroline-5-carboxylate reductase dimerisation
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
UDP-3-O-acylglucosamine N-acyltransferase
Potassium-transporting ATPase KdpC subunit
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Protein-PII uridylyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Mannose-6-phosphate isomerase type II C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Holliday junction branch migration complex subunit RuvA
Formamidopyrimidine-DNA glycosylase catalytic
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Inner membrane protein YgaP-like transmembrane
Manganese/iron superoxide dismutase C-terminal
Cytochrome C biogenesis protein transmembrane
Pyruvate phosphate dikinase AMP/ATP-binding
Release factor glutamine methyltransferase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Putative pyruvate, phosphate dikinase regulatory protein
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Glycoside hydrolase family 57 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Contractile injection system tube protein N-terminal
Nuclear transport factor 2 family protein
6-hydroxymethylpterin diphosphokinase MptE-like
CRISPR-associated protein Cas6 C-terminal
3-isopropylmalate dehydratase large subunit
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA 2-O ribose methyltransferase substrate binding
Type I restriction modification DNA specificity
2-dehydro-3-deoxyphosphooctonate aldolase
Phosphoribosylformylglycinamidine cyclo-ligase
Formylmethanofuran dehydrogenase subunit E
Abnormal spindle-like microcephaly-associated protein ASH
Membrane iron-sulfur containing protein FtrD-like domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
DNA polymerase III delta subunit C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Glutamate-1-semialdehyde 2,1-aminomutase
Imidazole glycerol phosphate synthase subunit HisF
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Carboxy-S-adenosyl-L-methionine synthase
DNA-directed RNA polymerase subunit beta'
Ribosomal RNA small subunit methyltransferase H
Crossover junction endodeoxyribonuclease RuvC
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Type II secretion system protein GspC N-terminal
N-acetyl-gamma-glutamyl-phosphate reductase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Alanyl-transfer RNA synthetases family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
N-(5'-phosphoribosyl)anthranilate isomerase
FMN-dependent NADH:quinone oxidoreductase
CobB/CobQ-like glutamine amidotransferase
Regulator of nucleoside diphosphate kinase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Involved in allosteric activation by GTP
ATP-dependent Clp protease proteolytic subunit
3-methyl-2-oxobutanoate hydroxymethyltransferase
F420-non-reducing hydrogenase iron-sulfur subunit D
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Bifunctional purine biosynthesis protein PurH
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Methionyl-tRNA synthetase anticodon-binding
AB hydrolase-1 domain-containing protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
Periplasmic copper-binding protein NosD beta helix
Periplasmic copper-binding protein NosD beta helix domain-containing protein
Type 4 fimbrial biogenesis protein PilX N-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
S-adenosylmethionine-dependent methyltransferase
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Could play a key role in the communication between the regulatory and the substrate sites
3-beta hydroxysteroid dehydrogenase/isomerase