DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycosyltransferase subfamily 4-like N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
O-(3'-phospho-DNA)-tyrosine intermediate
Glucosamine/galactosamine-6-phosphate isomerase
Peptidase M1 membrane alanine aminopeptidase
Terminase large subunit gp17-like C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Release factor glutamine methyltransferase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aminoacyl-transfer RNA synthetases class-II family profile
X-X-X-Leu-X-X-Gly heptad repeat-containing protein
L,D-transpeptidase catalytic domain-containing protein
Interaction with polymerase core subunit RpoC
Small ribosomal subunit protein uS4 N-terminal
Anthranilate synthase component I N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Methionyl-tRNA synthetase anticodon-binding
Penicillin-binding protein transpeptidase
Inosine/uridine-preferring nucleoside hydrolase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Alanyl-transfer RNA synthetases family profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Major facilitator superfamily (MFS) profile
6-phosphogluconate dehydrogenase C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Peptidoglycan recognition protein family
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Translation elongation factor P/YeiP central
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glycosyl transferase family 3 N-terminal
DNA replication/recombination mediator RecO N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Cytochrome b/b6 N-terminal region profile
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Putative Flp pilus-assembly TadG-like N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Reversibly protonated during proton transport
RND efflux pump membrane fusion protein barrel-sandwich
Prokaryotic-type class I peptide chain release factors
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphomannose isomerase type I catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Plays an important role in substrate specificity
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
CobB/CobQ-like glutamine amidotransferase
Helix-hairpin-helix DNA-binding motif class 1
NIF system FeS cluster assembly NifU N-terminal
Phosphocysteine intermediate; for EIIB activity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ribosome maturation factor RimP N-terminal
ABC transporter substrate-binding protein
Large ribosomal subunit protein uL6 alpha-beta
Gram-positive cocci surface proteins LPxTG domain-containing protein
Bacterial type II secretion system protein E
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
4'-phosphopantetheinyl transferase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cytochrome C biogenesis protein transmembrane
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA 2-O ribose methyltransferase substrate binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Cysteine sulfenic acid (-SOH) intermediate
Important for beta-aspartyl-AMP intermediate formation
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Nitrite/Sulfite reductase ferredoxin-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cell envelope-related transcriptional attenuator
Type II secretion system protein GspF domain-containing protein
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
RNA binding; important for wobble base 34 recognition
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Polymerase/histidinol phosphatase N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aminoacyl-tRNA synthetase class I anticodon-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Septum formation-related domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Carbamoyl-phosphate synthase small subunit N-terminal
Chromosomal replication initiator DnaA C-terminal
Sporulation transcription regulator WhiA N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
O-(5'-phospho-DNA)-tyrosine intermediate
YbaK/aminoacyl-tRNA synthetase-associated
ATP-dependent DNA helicase RecG C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphotransferase system enzyme I N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Peptide methionine sulphoxide reductase MsrA
Resolvase/invertase-type recombinase catalytic
Heat-inducible transcription repressor HrcA C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
5'-Nucleotidase C-terminal domain-containing protein
Electron transfer via tryptophanyl radical
Phosphoribosylformylglycinamidine synthase linker
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Exonuclease VII large subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Peptidase S9 prolyl oligopeptidase catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal