RND efflux pump membrane fusion protein barrel-sandwich
Lipocalin-like domain-containing protein
Major facilitator superfamily (MFS) profile
O-(3'-phospho-DNA)-tyrosine intermediate
O-(5'-phospho-DNA)-tyrosine intermediate
Neutral/alkaline non-lysosomal ceramidase N-terminal
Peptidase M1 membrane alanine aminopeptidase
DNA-binding beta-propeller fold protein YncE
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Peptidase S9 prolyl oligopeptidase catalytic
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Bacterial transcription activator effector binding
6-phosphogluconate dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
TonB-dependent receptor-like beta-barrel
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp central
Alpha-L-rhamnosidase six-hairpin glycosidase
Release factor glutamine methyltransferase N-terminal
Interaction with polymerase core subunit RpoC
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Membrane fusion protein biotin-lipoyl like
Schiff-base intermediate with substrate; via pyruvic acid
Nitrite/Sulfite reductase ferredoxin-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Bacterial type II secretion system protein E
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Right handed beta helix domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RNA polymerase sigma factor 70 region 4 type 2
Calcium-dependent phosphoinositide phospholipase C
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Mannose-6-phosphate isomerase type II C-terminal
Glycine zipper domain-containing protein
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Phosphoribosylformylglycinamidine synthase linker
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Glycoside hydrolase family 31 N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
YbaK/aminoacyl-tRNA synthetase-associated
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyridoxamine 5'-phosphate oxidase putative
Important for interaction with partner proteins
Oligogalacturonate lyase domain-containing protein
Abnormal spindle-like microcephaly-associated protein ASH
Outer membrane lipoprotein-sorting protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tetratricopeptide TPR_1 repeat-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Outer membrane protein beta-barrel domain-containing protein
Tryptophan synthase beta chain-like PALP
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Heme-copper oxidase subunit III family profile
Soil-associated protein, TIGR03435 family
3-keto-disaccharide hydrolase domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
Sulfatase-modifying factor enzyme domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Thioredoxin-like fold domain-containing protein
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
TonB-dependent receptor-like beta-barrel domain-containing protein
Glycosyl transferase family 28 C-terminal
NfeD-like C-terminal domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Could be important to modulate the pK values of the two catalytic cysteine residues
P-type conjugative transfer protein TrbJ
Aminoacyl-transfer RNA synthetases class-II family profile
SGNH hydrolase-type esterase domain-containing protein
Terminase large subunit gp17-like C-terminal
Polysaccharide chain length determinant N-terminal
Histidine-specific methyltransferase SAM-dependent
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Beta-hexosaminidase eukaryotic type N-terminal
40-residue YVTN family beta-propeller repeat protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Proton acceptor; for glutaminase activity
PBS lyase HEAT domain protein repeat-containing protein
Sortilin N-terminal domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA replication/recombination mediator RecO N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Type II restriction endonuclease EcoO109IR
PEP-CTERM protein-sorting domain-containing protein
CagE TrbE VirB component of type IV transporter system central
DNA-directed DNA polymerase family A palm
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Exonuclease VII large subunit C-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alpha galactosidase C-terminal beta sandwich
Large ribosomal subunit protein uL15/eL18
Carboxypeptidase regulatory-like domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Reversibly protonated during proton transport
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Peptide methionine sulphoxide reductase MsrA
N-sulphoglucosamine sulphohydrolase C-terminal
RNA 2-O ribose methyltransferase substrate binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
S-adenosylmethionine-dependent methyltransferase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Asl1-like glycosyl hydrolase catalytic domain-containing protein
Peptidase MA-like domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Lactate utilization protein B C-terminal
Phosphomannose isomerase type I catalytic
3-hydroxyacyl-CoA dehydrogenase NAD binding
RlpA-like protein double-psi beta-barrel
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycosyltransferase family 28 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Type IV secretion system coupling protein TraD DNA-binding
Glycosyl transferase family 3 N-terminal
Ysc84 actin-binding domain-containing protein
Pyrimidine nucleoside phosphorylase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Putative adhesin domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glucosamine/galactosamine-6-phosphate isomerase
ABC-type glycine betaine transport system substrate-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
HicB-like antitoxin of toxin-antitoxin system
Molybdopterin cofactor biosynthesis C (MoaC)
Glycoside hydrolase family 42 N-terminal
Membrane iron-sulfur containing protein FtrD-like
DNA polymerase III beta sliding clamp N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Penicillin-binding protein transpeptidase
Glucose-methanol-choline oxidoreductase C-terminal
Transposase IS116/IS110/IS902 C-terminal
Beta-hexosaminidase bacterial type N-terminal
NIF system FeS cluster assembly NifU N-terminal
Glycine cleavage T-protein C-terminal barrel
Flagella basal body P-ring formation protein FlgA C-terminal domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Plays an important role in substrate specificity
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Signal transduction histidine kinase internal region
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
DNA mismatch repair proteins mutS family
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glycoside hydrolase family 57 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Carbohydrate-binding domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Translation elongation factor P/YeiP central
Prepilin type IV endopeptidase peptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL2 C-terminal
Polysaccharide biosynthesis protein C-terminal
Glycosyl hydrolase family 30 beta sandwich
Alginate lyase domain-containing protein
1,4-alpha-glucan branching enzyme C-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
General stress protein FMN-binding split barrel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Oxidoreductase molybdopterin-binding domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
RNA binding; important for wobble base 34 recognition
Thiol:disulfide interchange protein DsbD N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Gp5/Type VI secretion system Vgr protein OB-fold
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Anthranilate synthase component I N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Formylmethanofuran dehydrogenase subunit E
Solute-binding protein family 3/N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Chromosomal replication initiator DnaA C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Positions MEP for the nucleophilic attack
Alanyl-transfer RNA synthetases family profile
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyruvate dehydrogenase E1 component middle
SMP-30/Gluconolaconase/LRE-like region-containing protein