Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL15/eL18
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Outer membrane protein beta-barrel domain-containing protein
General stress protein FMN-binding split barrel
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
TonB-dependent receptor plug domain-containing protein
TonB-dependent receptor-like beta-barrel
Glycosyltransferase subfamily 4-like N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Polysaccharide biosynthesis protein C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Curlin associated repeat-containing protein
Type IX secretion system membrane protein, PorP/SprF family
Ribosomal RNA adenine methylase transferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
Transposase IS116/IS110/IS902 C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Secretion system C-terminal sorting domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycine cleavage T-protein C-terminal barrel
3-keto-disaccharide hydrolase domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Saccharopine dehydrogenase-like C-terminal
DNA replication/recombination mediator RecO N-terminal
Major facilitator superfamily (MFS) profile
Phosphoadenosine phosphosulphate reductase
Lipocalin-like domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Peptidase M1 membrane alanine aminopeptidase
O-(5'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Histidine kinase domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
AMP-activated protein kinase glycogen-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Aminoacyl-transfer RNA synthetases class-II family profile
Type I restriction enzyme R protein N-terminal
Sialate O-acetylesterase domain-containing protein
3-hydroxyacyl-CoA dehydrogenase NAD binding
NADH:ubiquinone oxidoreductase 30kDa subunit
FAD-dependent oxidoreductase 2 FAD binding
O-(3'-phospho-DNA)-tyrosine intermediate
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Anthranilate synthase component I N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Reversibly protonated during proton transport
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Tryptophan synthase beta chain-like PALP
Aromatic hydrocarbon degradation membrane protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Trigger factor ribosome-binding bacterial
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
DNA mismatch repair proteins mutS family
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Resolvase/invertase-type recombinase catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Glycoside hydrolase family 5 domain-containing protein
Penicillin-binding protein transpeptidase
40-residue YVTN family beta-propeller repeat-containing protein
NIF system FeS cluster assembly NifU N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Signal transduction histidine kinase internal region
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycoside hydrolase family 57 N-terminal
Type IX secretion system membrane protein PorP/SprF
Ribose-phosphate pyrophosphokinase N-terminal
SusD/RagB family nutrient-binding outer membrane lipoprotein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RagB/SusD family nutrient uptake outer membrane protein
Translation elongation factor P/YeiP central
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Translation elongation factor EFTs/EF1B dimerisation
Mandelate racemase/muconate lactonizing enzyme C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glutathionylspermidine synthase pre-ATP-grasp-like
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Carboxypeptidase regulatory-like domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Na+/H+ antiporter MnhB subunit-related protein
ABC transporter substrate-binding protein
Glycosyl hydrolase family 30 beta sandwich
Sodium/calcium exchanger membrane region
Putative oxidoreductase/dehydrogenase Rossmann-like
Could be important to modulate the pK values of the two catalytic cysteine residues
Nucleophile; cysteine thiosulfonate intermediate
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Nucleotidyltransferase-Associated Rossmannoid Fold
Nucleotidyltransferase-Associated Rossmannoid Fold domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Solute-binding protein family 3/N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Polysaccharide biosynthesis protein CapD-like
Shikimate dehydrogenase substrate binding N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Haem-binding uptake Tiki superfamily ChaN
UDP N-acetylglucosamine O-acyltransferase C-terminal
Chromosomal replication initiator DnaA C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Outer membrane lipoprotein-sorting protein
Mannose-6-phosphate isomerase type II C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ABC-type uncharacterised transport system
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Beta-hexosaminidase bacterial type N-terminal
Transition state stabilizer; via amide nitrogen
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Prokaryotic glutathione synthetase ATP-binding
Integral membrane protein YccS N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Alpha-D-phosphohexomutase alpha/beta/alpha
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Heme-copper oxidase subunit III family profile
Alanyl-transfer RNA synthetases family profile
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Prokaryotic-type class I peptide chain release factors
NIF system FeS cluster assembly NifU C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
AraC-type arabinose-binding/dimerisation
TRAP C4-dicarboxylate transport system permease DctM subunit
Activator of Hsp90 ATPase homologue 1-like C-terminal
Peptide methionine sulphoxide reductase MsrA
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Peptidoglycan recognition protein family
Fibronectin type-III domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Chitobiase/beta-hexosaminidases N-terminal
S-adenosylmethionine-dependent methyltransferase
Curli production assembly/transport component CsgF
PsbP C-terminal domain-containing protein
Murein L,D-transpeptidase catalytic domain family protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein bL9 C-terminal
Phosphatidate phosphatase APP1 catalytic
Small ribosomal subunit protein uS4 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
LamG-like jellyroll fold domain-containing protein
DNA-directed DNA polymerase family A palm
Quercetin 2,3-dioxygenase C-terminal cupin
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Sulfatase-modifying factor enzyme domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Plays an important role in substrate specificity
Peptide methionine sulfoxide reductase MsrB
ATP synthase F1 complex delta/epsilon subunit N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Schiff-base intermediate with acetaldehyde
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Water stress and hypersensitive response
Homogentisate 1,2-dioxygenase N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Inner membrane protein YgaP-like transmembrane
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Peptidase M14 carboxypeptidase A domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyruvate dehydrogenase E1 component middle
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gly-cisPro motif, important for rejection of L-amino acids
4'-phosphopantetheinyl transferase N-terminal
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Survival protein SurE-like phosphatase/nucleotidase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Positions MEP for the nucleophilic attack
S-adenosyl-L-homocysteine hydrolase NAD binding
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Right handed beta helix domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Type 1 periplasmic binding fold superfamily protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA 2-O ribose methyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Polysaccharide chain length determinant N-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL2 C-terminal
Sodium symporter small subunit predicted
Glycosyl hydrolase-like 10 domain-containing protein
Glycosyl-hydrolase 97 C-terminal oligomerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Endoribonuclease L-PSP/chorismate mutase-like
Proton acceptor; for glutaminase activity
Large ribosomal subunit protein uL6 alpha-beta
Outer membrane lipoprotein BamD-like domain-containing protein
Non-canonical purine NTP phosphatase/PRRC1
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phospholipase C/D domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Cytochrome C biogenesis protein transmembrane
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Alginate export domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
N6 adenine-specific DNA methyltransferase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
SGNH hydrolase-type esterase domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Nitrite/Sulfite reductase ferredoxin-like
tRNA pseudouridylate synthase B C-terminal
ATP-dependent DNA helicase RecG C-terminal