NADH:flavin oxidoreductase/NADH oxidase N-terminal
Prepilin type IV endopeptidase peptidase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Exonuclease VII large subunit C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Penicillin-binding protein transpeptidase
Major facilitator superfamily (MFS) profile
Methionyl-tRNA synthetase anticodon-binding
TonB-dependent receptor-like beta-barrel
RND efflux pump membrane fusion protein barrel-sandwich
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Tryptophan synthase beta chain-like PALP
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Release factor glutamine methyltransferase N-terminal
Peptidoglycan binding-like domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Prokaryotic-type class I peptide chain release factors
SUF system FeS cluster assembly SufBD N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Glycosyl transferase family 3 N-terminal
Important for beta-aspartyl-AMP intermediate formation
Signal transduction histidine kinase dimerisation/phosphoacceptor
Signal recognition particle SRP54 helical bundle
Ribose-phosphate pyrophosphokinase N-terminal
Phosphatidate phosphatase APP1 catalytic
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Glycosyltransferase subfamily 4-like N-terminal
Lipocalin-like domain-containing protein
Putative auto-transporter adhesin head GIN
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridoxamine 5'-phosphate oxidase putative
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Thymidylate synthase/dCMP hydroxymethylase
Peptidase S9 prolyl oligopeptidase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Polysaccharide biosynthesis protein C-terminal
TonB C-terminal domain-containing protein
Polysaccharide chain length determinant N-terminal
Small-conductance mechanosensitive channel
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Shikimate dehydrogenase substrate binding N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar motor switch protein FliN-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Right handed beta helix domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Quercetin 2,3-dioxygenase C-terminal cupin
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Na+/H+ antiporter MnhB subunit-related protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
DNA replication/recombination mediator RecO N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Essential for prephenate dehydratase activity
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Sodium/calcium exchanger membrane region
Plastid lipid-associated protein/fibrillin conserved
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
TonB-dependent receptor plug domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Outer membrane protein assembly factor BamD
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Acetyl-CoA dehydrogenase-like C-terminal
Spore coat protein U domain-containing protein
Alanyl-transfer RNA synthetases family profile
Endoribonuclease L-PSP/chorismate mutase-like
Outer membrane protein beta-barrel domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Peptidase M1 membrane alanine aminopeptidase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Tetrahydrodipicolinate-N-succinyltransferase chain A
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Alpha-glycerophosphate oxidase C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Glucosamine/galactosamine-6-phosphate isomerase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polysaccharide biosynthesis protein GumN
Small ribosomal subunit protein uS4 N-terminal
Photosynthetic reaction centre H subunit N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribosomal RNA adenine methylase transferase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Translation elongation factor P/YeiP central
Resolvase/invertase-type recombinase catalytic
Carboxypeptidase regulatory-like domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
RNA binding; important for wobble base 34 recognition
Proton acceptor; for glutaminase activity
Histidine phosphotransferase ChpT C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Glycine zipper domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Organic solvent tolerance-like N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Beta-lactamase-related domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Helix-hairpin-helix DNA-binding motif class 1
Bacterial type II secretion system protein E
Glucose-methanol-choline oxidoreductase N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cation-transporting P-type ATPase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Acyl-CoA dehydrogenase N-terminal bacteria
Beta-lactamase hydrolase-like protein phosphatase-like
Histidine-specific methyltransferase SAM-dependent
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Important for interaction with partner proteins
S-adenosylmethionine-dependent methyltransferase
NADH:ubiquinone oxidoreductase 30kDa subunit
Saccharopine dehydrogenase-like C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Prolyl 3,4-dihydroxylase TPA1/OFD1 N-terminal
Tail specific protease domain-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Interaction with polymerase core subunit RpoC
NADH:ubiquinone oxidoreductase chain 4 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Superoxide dismutase copper/zinc binding
Superoxide dismutase copper/zinc binding domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
peptide-methionine (R)-S-oxide reductase
O-(3'-phospho-DNA)-tyrosine intermediate
Pseudouridine synthase I TruA alpha/beta
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NAD(P) transhydrogenase alpha subunit C-terminal
Amidohydrolase-related domain-containing protein
Magnesium-protoporphyrin IX methyltransferase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Reversibly protonated during proton transport
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
DNA mismatch repair proteins mutS family
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL2 C-terminal
Heme-copper oxidase subunit III family profile
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Molybdopterin cofactor biosynthesis C (MoaC)
Glycine cleavage T-protein C-terminal barrel
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
Cobaltochelatase subunit CobS N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Plays an important role in substrate specificity
Poly-beta-hydroxybutyrate polymerase N-terminal
Polymerase/histidinol phosphatase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Carbamoyl-phosphate synthase small subunit N-terminal
PHA accumulation regulator DNA-binding N-terminal
Magnesium chelatase subunit H N-terminal
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein uL15/eL18
PhoD-like phosphatase metallophosphatase
Outer membrane lipoprotein-sorting protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Nitrite/Sulfite reductase ferredoxin-like
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Acetylserotonin O-methyltransferase dimerisation
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Thiolase-like protein type 1 additional C-terminal
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Electron transfer via tryptophanyl radical
Large ribosomal subunit protein uL6 alpha-beta
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phage tail collar domain-containing protein
N-end rule aminoacyl transferase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
TonB-dependent receptor-like beta-barrel domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Flagellar assembly protein FliH/Type III secretion system HrpE