Important for beta-aspartyl-AMP intermediate formation
Adenosylcobalamin biosynthesis, GlcG-related protein
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Flagellar assembly protein FliH/Type III secretion system HrpE
Moybdenum cofactor oxidoreductase dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gamma-glutamylcyclotransferase AIG2-like
Reversibly protonated during proton transport
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
TIGR03756 family integrating conjugative element protein
Succinate--CoA ligase [ADP-forming] subunit beta
Phosphate ABC transporter substrate-binding protein
N6 adenine-specific DNA methyltransferase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glutamate synthase alpha subunit C-terminal
Ribulose bisphosphate carboxylase small subunit
Solute-binding protein family 3/N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Outer membrane protein assembly factor BamA
Ribosomal RNA adenine methylase transferase N-terminal
Sodium/calcium exchanger membrane region
Release factor glutamine methyltransferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-252)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-98)
YbaK/aminoacyl-tRNA synthetase-associated
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
4-hydroxy-tetrahydrodipicolinate reductase
Essential for prephenate dehydratase activity
Gly-cisPro motif, important for rejection of L-amino acids
RND efflux pump membrane fusion protein barrel-sandwich
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Ion-translocating oxidoreductase complex subunit A
Arginine decarboxylase C-terminal helical
Bacterial type II secretion system protein E
Phosphoadenosine phosphosulphate reductase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Probable septum site-determining protein MinC
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Prokaryotic-type class I peptide chain release factors
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Zinc-regulated TonB-dependent outer membrane receptor
Probable glycine dehydrogenase (decarboxylating) subunit 1
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Tryptophan synthase beta chain-like PALP
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Major facilitator superfamily (MFS) profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ATP-dependent Clp protease ATP-binding subunit ClpX
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA mismatch repair proteins mutS family
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
UDP N-acetylglucosamine O-acyltransferase C-terminal
Inner membrane protein YgaP-like transmembrane
Endolytic peptidoglycan transglycosylase RlpA
Water stress and hypersensitive response
Ribosomal RNA large subunit methyltransferase H
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Na+/H+ antiporter MnhB subunit-related protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
N-end rule aminoacyl transferase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Transcription factor NikR nickel binding C-terminal
NIF system FeS cluster assembly NifU C-terminal
HupH hydrogenase expression protein C-terminal
Organic solvent tolerance-like N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyruvate phosphate dikinase AMP/ATP-binding
Serine aminopeptidase S33 domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Flagellar basal body rod protein N-terminal
Type I restriction modification DNA specificity
Polymerase/histidinol phosphatase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
DNA-directed RNA polymerase subunit omega
Holliday junction branch migration complex subunit RuvA
DNA polymerase III subunit delta C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Flavocytochrome c sulphide dehydrogenase flavin-binding
Oxygen-dependent coproporphyrinogen-III oxidase
Flagellar hook-length control protein-like C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Antitoxin Xre/MbcA/ParS-like toxin-binding
Putative conjugal transfer nickase/helicase TraI C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Cytochrome oxidase subunit II copper A binding
Ribosomal RNA small subunit methyltransferase J
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Phenylalanine--tRNA ligase alpha subunit
Type 4 fimbrial biogenesis protein PilX N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Sugar fermentation stimulation protein homolog
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with substrate; via pyruvic acid
Nucleic acid binding OB-fold tRNA/helicase-type
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Flagellar basal-body/hook protein C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
NIF system FeS cluster assembly NifU N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Gp5/Type VI secretion system Vgr protein OB-fold
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Type II secretion system protein GspI C-terminal
Probable glycine dehydrogenase (decarboxylating) subunit 2
Required for dimer formation and molybdate binding
Electron transfer via tryptophanyl radical
Alanyl-transfer RNA synthetases family profile
Fibronectin type-III domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glutamate-1-semialdehyde 2,1-aminomutase
4-hydroxy-tetrahydrodipicolinate synthase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Penicillin-binding protein transpeptidase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Gamma-butyrobetaine hydroxylase-like N-terminal
Carbamoyl-phosphate synthase small chain
6-phosphogluconate dehydrogenase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Outer-membrane lipoprotein carrier protein
YcgL domain-containing protein Tgr7_3126
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Ribulose bisphosphate carboxylase large chain
Bacteriophage tail tape measure N-terminal
3-isopropylmalate dehydratase small subunit
3-isopropylmalate dehydratase large subunit
High-affinity zinc uptake system protein ZnuA
Prepilin type IV endopeptidase peptidase
DNA-directed RNA polymerase subunit beta
Translocation and assembly module subunit TamA
Probable transcriptional regulatory protein Tgr7_2237
Membrane-bound lytic murein transglycosylase F
Quercetin 2,3-dioxygenase C-terminal cupin
Plays an important role in substrate specificity
Peptide methionine sulphoxide reductase MsrA
Cyclic pyranopterin monophosphate synthase
Dicarboxylate transport domain-containing protein
High frequency lysogenization protein HflD homolog
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
TonB-dependent receptor-like beta-barrel
Anthranilate synthase component I N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycosyl transferase family 3 N-terminal
L-cysteine S-thiosulfotransferase subunit SoxA
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Cation-transporting P-type ATPase N-terminal
Restriction endonuclease type I HsdR N-terminal
PEP-CTERM protein-sorting domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Probable peptidoglycan glycosyltransferase FtsW
NAD(P) transhydrogenase alpha subunit C-terminal
Ribosomal RNA large subunit methyltransferase E
ATP phosphoribosyltransferase regulatory subunit
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Cytochrome b561 bacterial/Ni-hydrogenase
N-acetyl-gamma-glutamyl-phosphate reductase
Precorrin-2 dehydrogenase /sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
TRAP transporter solute receptor, TAXI family
Pyridine nucleotide-disulphide oxidoreductase dimerisation
tRNA N6-adenosine threonylcarbamoyltransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Iron-sulfur cluster assembly protein CyaY
Ysc84 actin-binding domain-containing protein
Polyribonucleotide nucleotidyltransferase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Chromosomal replication initiator DnaA C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Outer membrane protein beta-barrel domain-containing protein
Peptide methionine sulfoxide reductase MsrB
Cation-transporting P-type ATPase C-terminal
Ion-translocating oxidoreductase complex subunit E
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Holliday junction branch migration complex subunit RuvB
Outer membrane protein assembly factor BamD
Urease accessory protein UreH-like transmembrane
Gfo/Idh/MocA-like oxidoreductase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Positions MEP for the nucleophilic attack
Thiol:disulfide interchange protein DsbD
RNA binding; important for wobble base 34 recognition
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Chromosomal replication initiator protein DnaA
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Type II secretion system protein GspG C-terminal
4-hydroxythreonine-4-phosphate dehydrogenase
Important for substrate binding and specificity
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
DNA replication/recombination mediator RecO N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Putative regulatory protein FmdB Zinc ribbon
Sodium symporter small subunit predicted
Could play a key role in the communication between the regulatory and the substrate sites
Cell division topological specificity factor
Haem-binding uptake Tiki superfamily ChaN
O-(3'-phospho-DNA)-tyrosine intermediate
Glycoside hydrolase family 57 N-terminal
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Flagellar motor switch protein FliN-like C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Important for interaction with partner proteins
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large-conductance mechanosensitive channel
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA-directed DNA polymerase family A palm
Formate-dependent phosphoribosylglycinamide formyltransferase
Glycine cleavage T-protein C-terminal barrel
S-adenosylmethionine-dependent methyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Proton acceptor; for glutaminase activity
Disulphide bond isomerase DsbC/G N-terminal
Glutamyl-tRNA(Gln) amidotransferase subunit A
DNA-directed RNA polymerase subunit alpha
HicB-like antitoxin of toxin-antitoxin system
Glucosamine/galactosamine-6-phosphate isomerase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcriptional regulator AbiEi antitoxin N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Ribosomal RNA small subunit methyltransferase H
High potential iron-sulfur proteins family profile
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
2-dehydro-3-deoxyphosphooctonate aldolase
Imidazole glycerol phosphate synthase subunit HisF
Calcium/calmodulin-dependent protein kinase II association-domain
3-deoxy-manno-octulosonate cytidylyltransferase
ATP-dependent protease ATPase subunit HslU
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Transposase IS116/IS110/IS902 C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding