Tryptophan synthase beta chain-like PALP
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Bacterial type II secretion system protein E
Cytochrome c-type biogenesis protein CcmF C-terminal
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
RNA polymerase sigma factor 70 region 4 type 2
Proton acceptor; for glutaminase activity
Light-independent protochlorophyllide reductase subunit B
Flagellar basal body rod protein N-terminal
Major facilitator superfamily (MFS) profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Cob(I)alamin adenosyltransferase N-terminal
Peptide methionine sulphoxide reductase MsrA
Transcriptional regulator AbiEi antitoxin N-terminal
Sphingolipid delta4-desaturase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
ATP-dependent protease ATPase subunit HslU
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glycosyltransferase subfamily 4-like N-terminal
Protein-methionine-sulfoxide reductase catalytic subunit MsrP
ATP-dependent Clp protease ATP-binding subunit ClpX
Cytochrome C biogenesis protein transmembrane
Glucosamine/galactosamine-6-phosphate isomerase
Cation-transporting P-type ATPase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ubiquinone biosynthesis O-methyltransferase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Heme-copper oxidase subunit III family profile
Imidazole glycerol phosphate synthase subunit HisF
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
TonB-dependent receptor-like beta-barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Gamma-butyrobetaine hydroxylase-like N-terminal
Putative regulatory protein FmdB Zinc ribbon
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Caspase family p20 domain-containing protein
Glucan biosynthesis periplasmic MdoG C-terminal
Methanol dehydrogenase [cytochrome c] subunit 2
Holliday junction branch migration complex subunit RuvA
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Quercetin 2,3-dioxygenase C-terminal cupin
Flagella basal body P-ring formation protein FlgA C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Major facilitator superfamily associated
Plays an important role in substrate specificity
FMN-dependent NADH:quinone oxidoreductase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Activator of Hsp90 ATPase homologue 1-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Dinitrogenase iron-molybdenum cofactor biosynthesis
Lysozyme inhibitor LprI N-terminal domain-containing protein
Proteinase inhibitor I42 chagasin domain-containing protein
Photosynthetic reaction centre H subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Flagellar basal-body/hook protein C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyruvate phosphate dikinase AMP/ATP-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Prepilin type IV endopeptidase peptidase
4-hydroxy-tetrahydrodipicolinate reductase
Sulfite reductase [NADPH] hemoprotein beta-component
ABC-type glycine betaine transport system substrate-binding
Saccharopine dehydrogenase-like C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Endoribonuclease L-PSP/chorismate mutase-like
Aminoacyl-transfer RNA synthetases class-II family profile
Sodium/calcium exchanger membrane region
SUF system FeS cluster assembly SufBD N-terminal
Reversibly protonated during proton transport
ABC-type transport auxiliary lipoprotein component
Glycine cleavage T-protein C-terminal barrel
Phosphate starvation-inducible protein PsiF
RNA binding; important for wobble base 34 recognition
Electron transfer via tryptophanyl radical
Cytochrome b561 bacterial/Ni-hydrogenase
DNA-directed RNA polymerase subunit omega
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Lactate utilization protein B C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Anthranilate synthase component I N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Flagellar hook-basal body complex protein FliE
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Translation elongation factor P/YeiP central
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribosomal RNA large subunit methyltransferase H
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
tRNA pseudouridylate synthase B C-terminal
Invasion associated locus B family protein
Important for interaction with partner proteins
Prokaryotic-type class I peptide chain release factors
Glycine zipper domain-containing protein
Penicillin-binding protein transpeptidase
Phosphoribosylformylglycinamidine synthase subunit PurL
Ribulose bisphosphate carboxylase small subunit
N-end rule aminoacyl transferase C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Resolvase/invertase-type recombinase catalytic
Organic solvent tolerance-like N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Type 2A encapsulin shell protein SrpI-like
Flagellar motor switch protein FliN-like C-terminal
NIF system FeS cluster assembly NifU N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Solute-binding protein family 3/N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Could play a key role in the communication between the regulatory and the substrate sites
Polyribonucleotide nucleotidyltransferase
Signal transduction histidine kinase HWE region
Exonuclease VII large subunit C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Ribosomal RNA small subunit methyltransferase H
Mannose-6-phosphate isomerase type II C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Polysaccharide biosynthesis protein C-terminal
Acyltransferase MbtK/IucB-like conserved
Pyrroline-5-carboxylate reductase catalytic N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Probable periplasmic serine endoprotease DegP-like
N6 adenine-specific DNA methyltransferase N-terminal
UPF0173 metal-dependent hydrolase Msil_0741
Phage terminase large subunit N-terminal
Terminase large subunit gp17-like C-terminal
AB hydrolase-1 domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Transglycosylase SLT domain-containing protein
Methionyl-tRNA synthetase anticodon-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Important for autoinhibition of adenylyltransferase activity
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Type VI secretion system IcmF C-terminal
Type II secretion system protein GspG C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Autotransporter domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer
Alpha-L-rhamnosidase six-hairpin glycosidase
Putative glycogen debranching enzyme N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Sec-independent protein translocase protein TatA
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
RlpA-like protein double-psi beta-barrel
Involved in Mg(2+) ion dislocation from EF-Tu
tRNA N6-adenosine threonylcarbamoyltransferase
Pyrroline-5-carboxylate reductase dimerisation
Tetrahydrodipicolinate-N-succinyltransferase chain A
NAD(P) transhydrogenase alpha subunit C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Bacterial transcription activator effector binding
Endolytic peptidoglycan transglycosylase RlpA
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Alpha-D-phosphohexomutase alpha/beta/alpha
3-isopropylmalate dehydratase small subunit
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
3-isopropylmalate dehydratase large subunit
Glutamate synthase alpha subunit C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Histidine-specific methyltransferase SAM-dependent
DNA-directed RNA polymerase subunit alpha
Phenylalanine--tRNA ligase alpha subunit
Membrane fusion protein biotin-lipoyl like
Glutamyl-tRNA(Gln) amidotransferase subunit A
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Oxidoreductase molybdopterin-binding domain-containing protein
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Malonate/sodium symporter MadM subunit N-terminal
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Pyridoxamine 5'-phosphate oxidase putative
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
O-(3'-phospho-DNA)-tyrosine intermediate
RNA 2-O ribose methyltransferase substrate binding
NADH-rubredoxin oxidoreductase C-terminal
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Magnesium-protoporphyrin IX methyltransferase C-terminal
Histidine phosphotransferase ChpT C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Polymerase/histidinol phosphatase N-terminal
Holliday junction branch migration complex subunit RuvB
Chromosomal replication initiator DnaA C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Required for zinc-mediated homotetramerization and catalytic activity
NADH:ubiquinone oxidoreductase 30kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ABC transporter substrate-binding protein
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Potassium-transporting ATPase KdpC subunit
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Gp5/Type VI secretion system Vgr protein OB-fold
Light-independent protochlorophyllide reductase subunit B-like C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
PHA accumulation regulator DNA-binding N-terminal
Probable glycine dehydrogenase (decarboxylating) subunit 1
Type III restriction enzyme C-terminal endonuclease
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
O-(phosphoribosyl dephospho-coenzyme A)serine
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Nitrogenase molybdenum-iron protein beta chain N-terminal
Phosphoribosylformylglycinamidine cyclo-ligase
Glucose-methanol-choline oxidoreductase N-terminal
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Large-conductance mechanosensitive channel
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Crossover junction endodeoxyribonuclease RuvC
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Inner membrane protein YgaP-like transmembrane
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Choloylglycine hydrolase/NAAA C-terminal
AraC-type arabinose-binding/dimerisation
Essential for prephenate dehydratase activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Leucine-binding protein domain-containing protein
DNA-directed DNA polymerase family A palm
Interaction with polymerase core subunit RpoC
Polypeptide-transport-associated ShlB-type
Ribose-phosphate pyrophosphokinase N-terminal
Involved in allosteric activation by GTP
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Probable transcriptional regulatory protein Msil_2305
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Acetylserotonin O-methyltransferase dimerisation
NADPH-dependent 7-cyano-7-deazaguanine reductase
Alanyl-transfer RNA synthetases family profile
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
Interacts with tRNA; defines subfamily-specific binding signature
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding