Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Peptide methionine sulfoxide reductase MsrA
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
TRAP C4-dicarboxylate transport system permease DctM subunit
TonB-dependent receptor-like beta-barrel
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Major facilitator superfamily (MFS) profile
RNA binding; important for wobble base 34 recognition
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
O-(3'-phospho-DNA)-tyrosine intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Membrane fusion protein biotin-lipoyl like
Alpha-glycerophosphate oxidase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Outer membrane protein beta-barrel domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
RND efflux pump membrane fusion protein barrel-sandwich
Outer membrane lipoprotein-sorting protein
Disulphide bond isomerase DsbC/G N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Endolytic peptidoglycan transglycosylase RlpA
Arginine decarboxylase C-terminal helical
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL2 C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar hook-length control protein-like C-terminal
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glycosyltransferase subfamily 4-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Positions MEP for the nucleophilic attack
Polymerase/histidinol phosphatase N-terminal
Chalcone isomerase domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prokaryotic-type class I peptide chain release factors
Alpha-D-phosphohexomutase alpha/beta/alpha
Type II secretion system protein GspG C-terminal
Water stress and hypersensitive response
Water stress and hypersensitive response domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Curli production assembly/transport component CsgG
Transcriptional regulator AbiEi antitoxin N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Translation elongation factor P/YeiP central
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Proton acceptor; for glutaminase activity
Penicillin-binding protein transpeptidase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
DNA-directed DNA polymerase family A palm
Mechanosensitive ion channel inner membrane
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
NADH-rubredoxin oxidoreductase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Membrane-bound lytic murein transglycosylase F
Solute-binding protein family 3/N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
RND type efflux pump involved in aminoglycoside resistance
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Plays an important role in substrate specificity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Polysaccharide biosynthesis protein CapD-like
Beta-lactamase hydrolase-like protein phosphatase-like
Membrane insertase YidC/Oxa/ALB C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Tryptophan synthase beta chain-like PALP
3D (Asp-Asp-Asp) domain-containing protein
Exonuclease VII large subunit C-terminal
Putative regulatory protein FmdB Zinc ribbon
Neutral/alkaline non-lysosomal ceramidase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sugar fermentation stimulation protein C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Bacterial surface antigen (D15) domain-containing protein
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Pyruvate dehydrogenase E1 component middle
Gamma-glutamylcyclotransferase AIG2-like
Flagellar motor switch protein FliN N-terminal
Flagellar motor switch protein FliN-like C-terminal
Glycine cleavage T-protein C-terminal barrel
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Bacterial transcription activator effector binding
Urease accessory protein UreH-like transmembrane
Urease accessory protein UreH-like transmembrane domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Anthranilate synthase component I N-terminal
Erythronate-4-phosphate dehydrogenase dimerisation
Survival protein SurE-like phosphatase/nucleotidase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Chromosomal replication initiator DnaA C-terminal
Acyltransferase MbtK/IucB-like conserved
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Nitrite/Sulfite reductase ferredoxin-like
Important for interaction with partner proteins
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Prepilin type IV endopeptidase peptidase
C-type lysozyme inhibitor domain-containing protein
Putative ATP-dependent zinc protease domain-containing protein
ABC transporter substrate-binding protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Essential for prephenate dehydratase activity
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Signal transduction histidine kinase internal region
Thiol:disulfide interchange protein DsbD
BREX system Lon protease-like BrxL N-terminal
Release factor glutamine methyltransferase N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Large ribosomal subunit protein uL6 alpha-beta
Phosphatidic acid phosphatase type 2/haloperoxidase
ATP-dependent DNA helicase RecG C-terminal
Heme-copper oxidase subunit III family profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
CobB/CobQ-like glutamine amidotransferase
Interaction with polymerase core subunit RpoC
Required for zinc-mediated homotetramerization and catalytic activity
Peptide methionine sulphoxide reductase MsrA
PhoD-like phosphatase metallophosphatase
Small ribosomal subunit protein uS4 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
N-end rule aminoacyl transferase C-terminal
Divergent polysaccharide deacetylase family protein
Outer-membrane lipoprotein carrier protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Bacterial type II secretion system protein E
NIF system FeS cluster assembly NifU C-terminal
Butirosin biosynthesis protein H N-terminal
Flagella basal body P-ring formation protein FlgA
Cytochrome b561 bacterial/Ni-hydrogenase
RNA 2-O ribose methyltransferase substrate binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Regulator of nucleoside diphosphate kinase N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Electron transfer via tryptophanyl radical
Ribosomal RNA adenine methylase transferase N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Reversibly protonated during proton transport
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL15/eL18
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Alginate export domain-containing protein
Schiff-base intermediate with substrate; via pyruvic acid
Flagellar assembly protein FliH/Type III secretion system HrpE
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
SUF system FeS cluster assembly SufBD N-terminal
Histidine-specific methyltransferase SAM-dependent
Polysaccharide chain length determinant N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Type II secretion system protein GspC N-terminal
Type II secretion system protein GspC N-terminal domain-containing protein
Integrating conjugative element membrane protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA mismatch repair proteins mutS family
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Putative beta-barrel assembly-enhancing protease
Sodium/calcium exchanger membrane region
Pseudouridine synthase I TruA alpha/beta
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Lysidine-tRNA(Ile) synthetase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
S-adenosylmethionine-dependent methyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Adaptive response protein AidB N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA replication/recombination mediator RecO N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Alanyl-transfer RNA synthetases family profile
Shikimate dehydrogenase substrate binding N-terminal
Important for autoinhibition of adenylyltransferase activity
Integral membrane protein YccS N-terminal
Important for substrate binding and specificity
Quercetin 2,3-dioxygenase C-terminal cupin
Outer membrane beta-barrel domain-containing protein
Sodium symporter small subunit predicted
Choloylglycine hydrolase/NAAA C-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Glycosyl transferase family 3 N-terminal