Solute-binding protein family 3/N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
ABC transporter substrate-binding protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
ABC transporter substrate-binding protein PnrA-like
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Major facilitator superfamily (MFS) profile
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein uL2 C-terminal
RNA polymerase sigma factor 70 region 4 type 2
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Electron transfer via tryptophanyl radical
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-103)
Sugar fermentation stimulation protein C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aminoacyl-transfer RNA synthetases class-II family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Involved in allosteric activation by GTP
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Transglycosylase SLT domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
RND efflux pump membrane fusion protein barrel-sandwich
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transposase IS116/IS110/IS902 C-terminal
Translation elongation factor P/YeiP central
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glycine cleavage T-protein C-terminal barrel
Peptidoglycan binding-like domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tryptophan synthase beta chain-like PALP
Alpha-D-phosphohexomutase alpha/beta/alpha
Alanyl-transfer RNA synthetases family profile
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
Heat-inducible transcription repressor HrcA C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cytochrome b561 bacterial/Ni-hydrogenase
Membrane fusion protein biotin-lipoyl like
Cob(I)alamin adenosyltransferase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Organic solvent tolerance-like N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL15/eL18
Flagellar basal body rod protein N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycoside hydrolase family 42 N-terminal
Release factor glutamine methyltransferase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Resolvase/invertase-type recombinase catalytic
Survival protein SurE-like phosphatase/nucleotidase
TtsA-like Glycoside hydrolase family 108
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Plays an important role in substrate specificity
Prokaryotic-type class I peptide chain release factors
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Flagellar motor switch protein FliN-like C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
O-(3'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Essential for prephenate dehydratase activity
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
N-end rule aminoacyl transferase C-terminal
Glycosyl transferase family 3 N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
6-phosphogluconate dehydrogenase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Lipocalin/cytosolic fatty-acid binding domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Flagellar basal-body/hook protein C-terminal
Terminase large subunit gp17-like C-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Reversibly protonated during proton transport
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Heme-copper oxidase subunit III family profile
AB hydrolase-1 domain-containing protein
Cobaltochelatase subunit CobS N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Flagellar assembly protein FliH/Type III secretion system HrpE
Interaction with polymerase core subunit RpoC
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
L,D-transpeptidase catalytic domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Twin-arginine translocation pathway signal
Phosphodiester glycosidase domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Peptide methionine sulphoxide reductase MsrA
Sodium/calcium exchanger membrane region
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
N6 adenine-specific DNA methyltransferase N-terminal
Flagellar hook-length control protein-like C-terminal
Pyridoxamine 5'-phosphate oxidase putative
ABC-type glycine betaine transport system substrate-binding
Ionotropic glutamate receptor C-terminal
Cytochrome C biogenesis protein transmembrane
Phosphoribosylformylglycinamidine synthase linker
Type II secretion system protein GspE N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Beta-hexosaminidase bacterial type N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cytochrome c-type biogenesis protein CcmF C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Endoribonuclease L-PSP/chorismate mutase-like
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Penicillin-binding protein transpeptidase
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Tetrahydrodipicolinate-N-succinyltransferase chain A
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Type II secretion system protein TadB-like N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
D-galactarate/Altronate dehydratase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Gly-cisPro motif, important for rejection of L-amino acids
O-(5'-phospho-DNA)-tyrosine intermediate
tRNA pseudouridylate synthase B C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pseudouridine synthase I TruA alpha/beta
Ysc84 actin-binding domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Methionyl-tRNA synthetase anticodon-binding
Chromosomal replication initiator DnaA C-terminal
RNA 2-O ribose methyltransferase substrate binding
peptide-methionine (R)-S-oxide reductase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
ATP synthase F1 complex delta/epsilon subunit N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Na+/H+ antiporter MnhB subunit-related protein
Carbamoyl-phosphate synthase small subunit N-terminal
SMODS-associated and fused to various effectors
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
NADH-rubredoxin oxidoreductase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Zinc-binding loop region of homing endonuclease
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Proline utilization A proline dehydrogenase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
DNA-directed DNA polymerase family A palm
CobB/CobQ-like glutamine amidotransferase
Could be important to modulate the pK values of the two catalytic cysteine residues
Aminoacyl-tRNA synthetase class I anticodon-binding
Bacterial type II secretion system protein E
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-lactamase hydrolase-like protein phosphatase-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
DNA replication/recombination mediator RecO N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Important for interaction with partner proteins
Pyrimidine nucleoside phosphorylase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal