Major facilitator superfamily (MFS) profile
Tat pathway signal sequence domain protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Cytochrome C biogenesis protein transmembrane
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Peptidase M1 membrane alanine aminopeptidase
Peptidase M15B domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
SUF system FeS cluster assembly SufBD N-terminal
General stress protein FMN-binding split barrel
Mandelate racemase/muconate lactonizing enzyme C-terminal
Acyltransferase MbtK/IucB-like conserved
Phosphomannose isomerase type I catalytic
Resolvase/invertase-type recombinase catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Peptidase S8/S53 domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Penicillin-binding protein transpeptidase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Membrane insertase YidC/Oxa/ALB C-terminal
Transposase IS116/IS110/IS902 C-terminal
RNA polymerase sigma factor 70 region 4 type 2
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Excalibur calcium-binding domain-containing protein
Phosphoribosylformylglycinamidine synthase linker
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Release factor glutamine methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Tryptophan synthase beta chain-like PALP
Nitrite/Sulfite reductase ferredoxin-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyruvate phosphate dikinase AMP/ATP-binding
Glycine cleavage T-protein C-terminal barrel
Glucose-methanol-choline oxidoreductase N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Gly-cisPro motif, important for rejection of L-amino acids
Cell envelope-related transcriptional attenuator
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl hydrolase family 13 catalytic domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Exonuclease VII large subunit C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Restriction system protein Mrr-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glucosamine/galactosamine-6-phosphate isomerase
Prepilin type IV endopeptidase peptidase domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
6-phosphogluconate dehydrogenase C-terminal
Solute-binding protein family 3/N-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Aminoacyl-transfer RNA synthetases class-II family profile
Cobalamin-independent methionine synthase MetE N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Positions MEP for the nucleophilic attack
Pyruvate dehydrogenase E1 component middle
Carbamoyl-phosphate synthase small subunit N-terminal
Pseudouridine synthase I TruA alpha/beta
Anthranilate synthase component I N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
NADH-rubredoxin oxidoreductase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphatidate phosphatase APP1 catalytic
DNA-directed DNA polymerase family A palm
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
YbaK/aminoacyl-tRNA synthetase-associated
Polysaccharide biosynthesis protein CapD-like
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Threonine/serine exporter-like N-terminal
Helix-hairpin-helix DNA-binding motif class 1
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
ABC-type glycine betaine transport system substrate-binding
Ionotropic glutamate receptor C-terminal
Transcription regulator AsnC/Lrp ligand binding
Bacterial type II secretion system protein E
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Large ribosomal subunit protein uL2 C-terminal
Phosphoadenosine phosphosulphate reductase
Peptide methionine sulphoxide reductase MsrA
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Heavy metal-binding domain-containing protein
Translation elongation factor P/YeiP central
Alternate-type signal peptide domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Shikimate dehydrogenase substrate binding N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
ABC transmembrane type-1 domain-containing protein
Phosphotransferase system enzyme I N-terminal
Phenol hydroxylase C-terminal dimerisation
Prokaryotic-type class I peptide chain release factors
Sodium/calcium exchanger membrane region
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
CobB/CobQ-like glutamine amidotransferase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Alanyl-transfer RNA synthetases family profile
ABC transporter substrate-binding protein PnrA-like
Putative oxidoreductase/dehydrogenase Rossmann-like
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Putative Flp pilus-assembly TadG-like N-terminal
Polysaccharide chain length determinant N-terminal
Cation-transporting P-type ATPase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cytochrome b/b6 N-terminal region profile
Methionyl-tRNA synthetase anticodon-binding
Activator of Hsp90 ATPase homologue 1-like C-terminal
Fibronectin type-III domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Beta-lactamase-related domain-containing protein
Plays an important role in substrate specificity
Large ribosomal subunit protein uL15/eL18
NIF system FeS cluster assembly NifU N-terminal
Beta-lactamase class A catalytic domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Peptidase M14 carboxypeptidase A domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
RNA binding; important for wobble base 34 recognition
Type I restriction enzyme R protein N-terminal
Small ribosomal subunit protein uS4 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Heat-inducible transcription repressor HrcA C-terminal
Polysaccharide biosynthesis protein C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ribose-phosphate pyrophosphokinase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Schiff-base intermediate with acetaldehyde
Glucose-methanol-choline oxidoreductase C-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glycosyl transferase family 3 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
L-seryl-tRNA selenium transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Schiff-base intermediate with substrate; via pyruvic acid
Superoxide dismutase copper/zinc binding
Large ribosomal subunit protein uL6 alpha-beta
Myo-inositol-1-phosphate synthase GAPDH-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Lactate utilization protein B C-terminal
Trigger factor ribosome-binding bacterial
Polymerase/histidinol phosphatase N-terminal
Bacterial transcription activator effector binding
Sporulation transcription regulator WhiA N-terminal
Reversibly protonated during proton transport
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Thymidylate synthase/dCMP hydroxymethylase