Transcription factor NikR nickel binding C-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Polymerase/histidinol phosphatase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Type I restriction modification DNA specificity
Cytochrome c-type biogenesis protein CcmF C-terminal
Major facilitator superfamily (MFS) profile
Bacterial type II secretion system protein E
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
HicB-like antitoxin of toxin-antitoxin system
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Acetylserotonin O-methyltransferase dimerisation
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Anthranilate synthase component I N-terminal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Glucose-6-phosphate isomerase prokaryote
Transcription factor CBF/NF-Y/archaeal histone
Siroheme decarboxylase AsnC-like ligand binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein uL15/eL18
Aminoacyl-transfer RNA synthetases class-II family profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA-directed RNA polymerase RBP11-like dimerisation
DNA-directed RNA polymerase subunit 2 hybrid-binding
Serine/threonine specific protein phosphatases
Aspartate/homoserine dehydrogenase NAD-binding
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Tryptophan synthase beta chain-like PALP
Schiff-base intermediate with dihydroxyacetone-P
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Transcription regulator AsnC/Lrp ligand binding
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Cytochrome b561 bacterial/Ni-hydrogenase
RNA 2-O ribose methyltransferase substrate binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Large ribosomal subunit protein uL2 C-terminal
Water stress and hypersensitive response
DNA mismatch repair proteins mutS family
Pyrroline-5-carboxylate reductase dimerisation
Translation elongation factor IF5A C-terminal
Exosome complex component CSL4 C-terminal
Terminase large subunit gp17-like C-terminal
Probable transposase IS891/IS1136/IS1341
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyltransferase subfamily 4-like N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Aldehyde ferredoxin oxidoreductase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glutamate synthase alpha subunit C-terminal
F420-non-reducing hydrogenase iron-sulfur subunit D
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cytochrome oxidase subunit II copper A binding
Non-canonical purine NTP phosphatase/PRRC1
TRAP C4-dicarboxylate transport system permease DctM subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Dinitrogenase iron-molybdenum cofactor biosynthesis
NADH:ubiquinone oxidoreductase 30kDa subunit
6-hydroxymethylpterin diphosphokinase MptE-like
Carbamoyl-phosphate synthase small subunit N-terminal
Alanyl-transfer RNA synthetases family profile
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
tRNA nucleotidyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Cation-transporting P-type ATPase N-terminal
Archaeal glycosylation protein B peripheral
Increases nucleophilicity of active site Cys
DNA polymerase II large subunit DP2 N-terminal
Damage-control phosphatase ARMT1-like metal-binding
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Could be important to modulate the pK values of the two catalytic cysteine residues
Small ribosomal subunit protein uS15 N-terminal
RNA 3'-terminal phosphate cyclase insert
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Plays an important role in substrate specificity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pseudouridine synthase I TruA alpha/beta
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
NADH-rubredoxin oxidoreductase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Zn-dependent metallo-hydrolase RNA specificity
Quinolinate phosphoribosyl transferase C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
ABC transporter substrate-binding protein PnrA-like
MPBQ/MBSQ family SAM-binding methyltransferase profile
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
rRNA small subunit methyltransferase F RNA-binding PUA-like
Large ribosomal subunit protein uL6 alpha-beta
Small ribosomal subunit protein uS4 N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Formylmethanofuran dehydrogenase subunit E
Methanogenesis regulatory protein FilR1 middle
Phosphatidic acid phosphatase type 2/haloperoxidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Sodium/calcium exchanger membrane region
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Large ribosomal subunit protein uL10-like insertion
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
DNA polymerase alpha/delta/epsilon subunit B
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
UDP N-acetylglucosamine O-acyltransferase C-terminal