Acyl-CoA dehydrogenase/oxidase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Schiff-base intermediate with acetaldehyde
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Small ribosomal subunit protein uS4 N-terminal
Sporulation transcription regulator WhiA N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
RNA polymerase sigma factor 70 region 4 type 2
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphoribosylformylglycinamidine synthase linker
Major facilitator superfamily (MFS) profile
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
ABC transporter substrate-binding protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase S9 prolyl oligopeptidase catalytic
NIF system FeS cluster assembly NifU N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL6 alpha-beta
Pyridoxamine 5'-phosphate oxidase putative
Thiolase-like protein type 1 additional C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
O-(5'-phospho-DNA)-tyrosine intermediate
DNA-directed DNA polymerase family A palm
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Resuscitation-promoting factor core lysozyme-like
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
FAD-dependent oxidoreductase 2 FAD binding
Translation elongation factor P/YeiP central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Putative regulatory protein FmdB Zinc ribbon
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Phosphoadenosine phosphosulphate reductase
Penicillin-binding protein transpeptidase
Phosphatidylglycerol lysyltransferase C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Interaction with polymerase core subunit RpoC
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Sporulation stage II protein D amidase enhancer LytB N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Gly-cisPro motif, important for rejection of L-amino acids
Survival protein SurE-like phosphatase/nucleotidase
6-phosphogluconate dehydrogenase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Putative oxidoreductase/dehydrogenase Rossmann-like
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
SUF system FeS cluster assembly SufBD N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Cation-transporting P-type ATPase N-terminal
Glutamate synthase alpha subunit C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Polysaccharide chain length determinant N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyltransferase subfamily 4-like N-terminal
Solute-binding protein family 3/N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N6 adenine-specific DNA methyltransferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Alanyl-transfer RNA synthetases family profile
Membrane insertase YidC/Oxa/ALB C-terminal
Tryptophan synthase beta chain-like PALP
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Reversibly protonated during proton transport
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Glycosyl transferase family 3 N-terminal
Pyruvate dehydrogenase E1 component middle
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Lactate utilization protein B C-terminal
Important for beta-aspartyl-AMP intermediate formation
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Peptide methionine sulphoxide reductase MsrA
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Plays an important role in substrate specificity
Transcription regulator AsnC/Lrp ligand binding
Important for substrate specificity; cannot use PPi as phosphoryl donor
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Removed in mature form; by autocatalysis
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cytochrome b/b6 N-terminal region profile
Peptidoglycan recognition protein family
Adaptive response protein AidB N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Prokaryotic-type class I peptide chain release factors
Anthranilate synthase component I N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Histidine-specific methyltransferase SAM-dependent
RNA 2-O ribose methyltransferase substrate binding
Pyrimidine nucleoside phosphorylase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Choloylglycine hydrolase/NAAA C-terminal
Phosphotransferase system enzyme I N-terminal
Chromosomal replication initiator DnaA C-terminal
Type III restriction enzyme C-terminal endonuclease
PhoD-like phosphatase metallophosphatase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Shikimate dehydrogenase substrate binding N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Methionyl-tRNA synthetase anticodon-binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
NAD(P) transhydrogenase alpha subunit C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Putative Flp pilus-assembly TadG-like N-terminal
Pseudouridine synthase I TruA alpha/beta
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Bacterial transcription activator effector binding
Sodium/calcium exchanger membrane region
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Anti-sigma-D factor RsdA sigma factor binding region
Na+/H+ antiporter MnhB subunit-related protein
Positions MEP for the nucleophilic attack
Superoxide dismutase copper/zinc binding
DnaJ homologue subfamily C member 28 conserved
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Cysteine sulfenic acid (-SOH) intermediate
ABC-type glycine betaine transport system substrate-binding
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Exonuclease VII large subunit C-terminal
Phosphomannose isomerase type I catalytic
Peptidase M1 membrane alanine aminopeptidase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Heat-inducible transcription repressor HrcA C-terminal
Resuscitation-promoting factor Rpf1 C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Large ribosomal subunit protein uL15/eL18
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Type I restriction modification DNA specificity
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Myo-inositol-1-phosphate synthase GAPDH-like
Ribose-phosphate pyrophosphokinase N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycine cleavage T-protein C-terminal barrel
Cardiolipin synthase N-terminal domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein uL2 C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation