Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA mismatch repair proteins mutS family
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Major facilitator superfamily (MFS) profile
Integral membrane protein YccS N-terminal
Twin-arginine translocation signal domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Beta-hexosaminidase bacterial type N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
TonB-dependent receptor-like beta-barrel
Aspartate/homoserine dehydrogenase NAD-binding
Large-conductance mechanosensitive channel
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Urease accessory protein UreH-like transmembrane
Involved in Mg(2+) ion dislocation from EF-Tu
Glucosamine/galactosamine-6-phosphate isomerase
Chalcone isomerase domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Alpha galactosidase C-terminal beta sandwich
Nitrite/Sulfite reductase ferredoxin-like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Glycosyl-hydrolase 97 C-terminal oligomerisation
Carbamoyl-phosphate synthase small subunit N-terminal
Sec-independent protein translocase protein TatA
Glycosyltransferase subfamily 4-like N-terminal
Glycine cleavage T-protein C-terminal barrel
AB hydrolase-1 domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Chromosomal replication initiator DnaA C-terminal
Ribosomal RNA small subunit methyltransferase G
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Tryptophan synthase beta chain-like PALP
Holliday junction branch migration complex subunit RuvB
T9SS C-terminal target domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gliding motility protein SprA N-terminal
Nuclear transport factor 2 family protein
Heme-copper oxidase subunit III family profile
Glycoside hydrolase family 31 N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
3-beta hydroxysteroid dehydrogenase/isomerase
CD-NTase associated protein 4-like DNA endonuclease
Membrane insertase YidC/Oxa/ALB C-terminal
Concanavalin A-like lectin/glucanase superfamily protein
Histidine-specific methyltransferase SAM-dependent
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
NIF system FeS cluster assembly NifU C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Trigger factor ribosome-binding bacterial
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Signal transduction histidine kinase internal region
Gamma-glutamylcyclotransferase AIG2-like
Type IX secretion system membrane protein PorP/SprF
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Polysaccharide biosynthesis protein C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Insertion element IS1 protein InsA helix-turn-helix
Phosphatidylglycerol lysyltransferase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Important for beta-aspartyl-AMP intermediate formation
General stress protein FMN-binding split barrel
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Beta-xylosidase C-terminal Concanavalin A-like
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Formamidopyrimidine-DNA glycosylase catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
ABC-type uncharacterised transport system
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Polymerase/histidinol phosphatase N-terminal
Type IX secretion system protein PorV domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glycosyl transferase family 28 C-terminal
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Alpha-glycerophosphate oxidase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Bacterial bifunctional deaminase-reductase C-terminal
Secretion system C-terminal sorting domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA-directed RNA polymerase subunit beta
Phosphatidic acid phosphatase type 2/haloperoxidase
Ribonucleotide reductase large subunit C-terminal
Probable potassium transport system protein Kup
Carboxypeptidase-like regulatory domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Choloylglycine hydrolase/NAAA C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Type 2A encapsulin shell protein SrpI-like
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Transposase IS116/IS110/IS902 C-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Glycosyl hydrolase family 30 beta sandwich
RNA 2-O ribose methyltransferase substrate binding
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Ribose-phosphate pyrophosphokinase N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Curli production assembly/transport component CsgF
Prokaryotic-type class I peptide chain release factors
Small ribosomal subunit biogenesis GTPase RsgA
Acyltransferase MbtK/IucB-like conserved
Phenylalanine--tRNA ligase alpha subunit
Phosphoethanolamine transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
3-isopropylmalate dehydratase large subunit
Peptide methionine sulphoxide reductase MsrA
DNA-directed DNA polymerase family A palm
Bacterial transcription activator effector binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyrroline-5-carboxylate reductase dimerisation
AMP-activated protein kinase glycogen-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Type I restriction enzyme R protein N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Important for autoinhibition of adenylyltransferase activity
Polysaccharide chain length determinant N-terminal
Type I restriction modification DNA specificity
Ribosomal RNA small subunit methyltransferase A
Enoyl-[acyl-carrier-protein] reductase [NADH]
Plays an important role in discriminating NADH against NADPH
Pyruvate phosphate dikinase AMP/ATP-binding
Gly-cisPro motif, important for rejection of L-amino acids
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-273)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-100)
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Peptidase M43 pregnancy-associated plasma-A
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RNA binding; important for wobble base 34 recognition
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Saccharopine dehydrogenase-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Quercetin 2,3-dioxygenase C-terminal cupin
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Homogentisate 1,2-dioxygenase N-terminal
Lipocalin-like domain-containing protein
Ribosomal RNA large subunit methyltransferase H
Putative auto-transporter adhesin head GIN
Resolvase/invertase-type recombinase catalytic
Cation-transporting P-type ATPase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Inner membrane protein YgaP-like transmembrane
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Probable dual-specificity RNA methyltransferase RlmN
Putative auto-transporter adhesin head GIN domain-containing protein
Probable nicotinate-nucleotide adenylyltransferase
Cationic amino acid transporter C-terminal
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Potassium-transporting ATPase KdpC subunit
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glycosyl-hydrolase family 116 catalytic region
Glycosyl-hydrolase family 116 catalytic region domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Plays an important role in maintaining the position of the catalytic nucleophile
T9SS type A sorting domain-containing protein
Penicillin-binding protein transpeptidase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
peptide-methionine (R)-S-oxide reductase
Lysidine-tRNA(Ile) synthetase C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Bacterial type II secretion system protein E
Limiting CO2-inducible protein B/C beta carbonyic anhydrase
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Carbohydrate-binding domain-containing protein
Curlin associated repeat-containing protein
Alpha-L-rhamnosidase six-hairpin glycosidase
Cytochrome b561 bacterial/Ni-hydrogenase
6-phosphogluconate dehydrogenase C-terminal
3-methyl-2-oxobutanoate hydroxymethyltransferase
Peptidase M1 membrane alanine aminopeptidase
Ribosomal RNA large subunit methyltransferase F
Alpha-D-phosphohexomutase alpha/beta/alpha
Protein-L-isoaspartate O-methyltransferase
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Ribosomal protein uS12 methylthiotransferase RimO
Probable molybdenum cofactor guanylyltransferase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Sodium/calcium exchanger membrane region
Polyribonucleotide nucleotidyltransferase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Antitoxin component YwqK of YwqJK toxin-antitoxin module
Glutamate-1-semialdehyde 2,1-aminomutase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glycoside hydrolase GH146 substrate-binding
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Imidazole glycerol phosphate synthase subunit HisF
CarboxypepD_reg-like domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Reversibly protonated during proton transport
ATP synthase F1 complex delta/epsilon subunit N-terminal
3-deoxy-manno-octulosonate cytidylyltransferase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
N6 adenine-specific DNA methyltransferase N-terminal
Plays an important role in substrate specificity
UDP-N-acetylenolpyruvoylglucosamine reductase
DNA topoisomerase I catalytic core eukaryotic-type
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Alginate export domain-containing protein
Thioredoxin-like fold domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Diiron non-heme beta-hydroxylase N-terminal
Bacterial alpha-L-rhamnosidase N-terminal
Probable transcriptional regulatory protein Fjoh_2560
Electron transfer via tryptophanyl radical
Leucyl/phenylalanyl-tRNA--protein transferase
UPF0173 metal-dependent hydrolase Fjoh_2786
Cysteine sulfenic acid (-SOH) intermediate
DNA-directed RNA polymerase subunit beta'
Nicotinamide phosphoribosyltransferase N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Phosphatidate phosphatase APP1 catalytic
Butirosin biosynthesis protein H N-terminal
Thiamin pyrophosphokinase thiamin-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Sialate O-acetylesterase domain-containing protein
Adenylyl/Guanylyl and SMODS C-terminal sensor
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Phosphomannose isomerase type I catalytic
Geranylgeranylglyceryl phosphate synthase
Carboxypeptidase regulatory-like domain-containing protein
Succinate--CoA ligase [ADP-forming] subunit beta
N-acetyl-gamma-glutamyl-phosphate reductase
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Potassium-transporting ATPase potassium-binding subunit
Transcription elongation factor GreA/GreB C-terminal