SGNH hydrolase-type esterase domain-containing protein
Major facilitator superfamily (MFS) profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
PhoD-like phosphatase metallophosphatase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Sodium/calcium exchanger membrane region
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Reversibly protonated during proton transport
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Plays an important role in substrate specificity
Important for beta-aspartyl-AMP intermediate formation
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Gram-positive cocci surface proteins LPxTG
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Docks into pockets in the proteasome alpha-ring
Alpha-D-phosphohexomutase alpha/beta/alpha
Small ribosomal subunit protein uS4 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glycosyltransferase subfamily 4-like N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Activator of Hsp90 ATPase homologue 1-like C-terminal
Probable dual-specificity RNA methyltransferase RlmN
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome b/b6 N-terminal region profile
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidase C39-like domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphatidate phosphatase APP1 catalytic
Prokaryotic-type class I peptide chain release factors
Glycosyltransferase family 28 N-terminal
Removed in mature form; by autocatalysis
Tryptophan synthase beta chain-like PALP
Acetylserotonin O-methyltransferase dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Histidine-specific methyltransferase SAM-dependent
NIF system FeS cluster assembly NifU N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Probable transcriptional regulatory protein Strop_1792
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Cytochrome C biogenesis protein transmembrane
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Chromosomal replication initiator DnaA C-terminal
Capsule synthesis protein CapA domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
N-terminal domain of peptidoglycan hydrolase CwlO-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
FAD-dependent oxidoreductase 2 FAD binding
Sporulation-specific cell division protein SsgB
It has a reduced activity, however, to a much lesser extent than the Y70T mutant.
Results in a 2-fold reduction of chlorinase activity.
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA-directed RNA polymerase subunit beta'
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Phosphatidic acid phosphatase type 2/haloperoxidase
Glutamyl-tRNA(Gln) amidotransferase subunit A
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Alpha-glycerophosphate oxidase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Pyridoxal 5'-phosphate synthase subunit PdxT
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
Ribosomal RNA adenine methylase transferase N-terminal
Pseudouridine synthase I TruA alpha/beta
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
ABC-type glycine betaine transport system substrate-binding
Peptidase S9 prolyl oligopeptidase catalytic
Glycosyl transferase family 28 C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Rubrerythrin diiron-binding domain-containing protein
Beta-hexosaminidase bacterial type N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
CobB/CobQ-like glutamine amidotransferase
RNA 2-O ribose methyltransferase substrate binding
3-isopropylmalate dehydratase small subunit
Holliday junction branch migration complex subunit RuvB
Cobalt-precorrin-5B C(1)-methyltransferase
Putative glycogen debranching enzyme N-terminal
Interaction with polymerase core subunit RpoC
Bacterial bifunctional deaminase-reductase C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Erythromycin biosynthesis protein CIII-like central
Phosphoadenosine phosphosulphate reductase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glycine cleavage T-protein C-terminal barrel
ABC transporter type 1 GsiC-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pyruvate phosphate dikinase AMP/ATP-binding
Sec-independent protein translocase protein TatA
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase M1 membrane alanine aminopeptidase
Positions MEP for the nucleophilic attack
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Nitrite/Sulfite reductase ferredoxin-like
YbaK/aminoacyl-tRNA synthetase-associated
6-phosphogluconate dehydrogenase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
4'-phosphopantetheinyl transferase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Heme-copper oxidase subunit III family profile
Carbamoyl-phosphate synthase small subunit N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphoribosylformylglycinamidine synthase linker
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
DNA replication/recombination mediator RecO N-terminal
Septum formation-related domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Glutamate-1-semialdehyde 2,1-aminomutase
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH:ubiquinone oxidoreductase 30kDa subunit
SUF system FeS cluster assembly SufBD N-terminal
Phosphomannose isomerase type I catalytic
Involved in ionization of N3 of dUMP, leading to its activation
DNA-directed DNA polymerase family A palm
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Periplasmic binding protein domain-containing protein
Acyltransferase MbtK/IucB-like conserved
Ribose-phosphate pyrophosphokinase N-terminal
Peptide methionine sulfoxide reductase MsrA
Holliday junction branch migration complex subunit RuvA
Thiamine pyrophosphate enzyme TPP-binding
Nucleophile; cysteine thiosulfonate intermediate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Putative regulatory protein FmdB Zinc ribbon
Diacylglycerol glucosyltransferase N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Increases nucleophilicity of active site Cys
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Penicillin-binding protein transpeptidase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Ribosomal protein uS12 methylthiotransferase RimO
Homogentisate 1,2-dioxygenase C-terminal
Ribosomal RNA small subunit methyltransferase H
Ribosomal RNA small subunit methyltransferase G
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyrimidine nucleoside phosphorylase C-terminal
Choice-of-anchor A domain-containing protein
Proton acceptor; for glutaminase activity
Solute-binding protein family 3/N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Imidazole glycerol phosphate synthase subunit HisF
N-acetyl-gamma-glutamyl-phosphate reductase
Formamidopyrimidine-DNA glycosylase catalytic
Succinate--CoA ligase [ADP-forming] subunit beta
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-276)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-128)
Transglycosylase SLT domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
L-seryl-tRNA selenium transferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA-directed RNA polymerase subunit omega
Na+/H+ antiporter MnhB subunit-related protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
DNA topoisomerase I catalytic core eukaryotic-type
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Phosphoinositide phospholipase C, Ca2+-dependent
NADH-rubredoxin oxidoreductase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Adaptive response protein AidB N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Transcription regulator AsnC/Lrp ligand binding
Cation-transporting P-type ATPase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
DNA primase/polymerase bifunctional N-terminal
ATP-dependent Clp protease ATP-binding subunit ClpX
Cytochrome oxidase subunit II copper A binding
Extracellular solute-binding protein, family 1
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar hook-length control protein FliK
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
Essential for prephenate dehydratase activity
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Polyribonucleotide nucleotidyltransferase
Schiff-base intermediate with substrate; via pyruvic acid
Thiopeptide-type bacteriocin biosynthesis
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Anthranilate synthase component I N-terminal
3-isopropylmalate dehydratase large subunit
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Resolvase/invertase-type recombinase catalytic
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Shikimate dehydrogenase substrate binding N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Endoribonuclease L-PSP/chorismate mutase-like
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase