Alanyl-transfer RNA synthetases family profile
Major facilitator superfamily (MFS) profile
Glycosyltransferase subfamily 4-like N-terminal
Rv2525c-like glycoside hydrolase-like domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Penicillin-binding protein transpeptidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Heat-inducible transcription repressor HrcA C-terminal
Glycine cleavage T-protein C-terminal barrel
Prokaryotic-type class I peptide chain release factors
Phosphatidate phosphatase APP1 catalytic
Thymidylate synthase/dCMP hydroxymethylase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Involved in ionization of N3 of dUMP, leading to its activation
Prealbumin-like fold domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gly-cisPro motif, important for rejection of L-amino acids
CobB/CobQ-like glutamine amidotransferase
Bacterial type II secretion system protein E
Essential for prephenate dehydratase activity
Sporulation transcription regulator WhiA N-terminal
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL15/eL18
Increases nucleophilicity of active site Cys
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ABC-type glycine betaine transport system substrate-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Solute-binding protein family 3/N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Phosphocysteine intermediate; for EIIB activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aminoacyl-transfer RNA synthetases class-II family profile
Important for substrate specificity; cannot use PPi as phosphoryl donor
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate
Pyruvate dehydrogenase E1 component middle
Translation elongation factor P/YeiP central
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL6 alpha-beta
RNA 2-O ribose methyltransferase substrate binding
Type I restriction modification DNA specificity
Threonine/serine exporter-like N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NIF system FeS cluster assembly NifU N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Anthranilate synthase component I N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Peptidoglycan recognition protein family
Peptidoglycan recognition protein family domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase S9 prolyl oligopeptidase catalytic
Inosine/uridine-preferring nucleoside hydrolase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Carbohydrate-binding domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gram-positive cocci surface proteins LPxTG
Gram-positive pilin subunit D1 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Cytochrome C biogenesis protein transmembrane
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RND efflux pump membrane fusion protein barrel-sandwich
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Heme-copper oxidase subunit III family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Interaction with polymerase core subunit RpoC
Important for beta-aspartyl-AMP intermediate formation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Release factor glutamine methyltransferase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Prepilin type IV endopeptidase peptidase
Plays an important role in substrate specificity
Membrane insertase YidC/Oxa/ALB C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Prokaryotic membrane lipoprotein lipid attachment site
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyl transferase family 3 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Schiff-base intermediate with acetaldehyde
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL2 C-terminal
Siderophore-interacting protein C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
Small ribosomal subunit protein uS4 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptide methionine sulphoxide reductase MsrA
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
6-phosphogluconate dehydrogenase C-terminal
Reversibly protonated during proton transport
RNA binding; important for wobble base 34 recognition
Chromosomal replication initiator DnaA C-terminal
Cell envelope-related transcriptional attenuator
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome oxidase subunit II copper A binding
Nucleophile; for GTP cyclohydrolase activity
Cytochrome b/b6 N-terminal region profile
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Putative host cell surface-exposed lipoprotein Ltp-like HTH region domain-containing protein
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial bifunctional deaminase-reductase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
N6 adenine-specific DNA methyltransferase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Gram-positive cocci surface proteins LPxTG domain-containing protein
DNA replication/recombination mediator RecO N-terminal
4'-phosphopantetheinyl transferase N-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Helix-hairpin-helix DNA-binding motif class 1
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Nitrite/Sulfite reductase ferredoxin-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Superoxide dismutase copper/zinc binding
YbaK/aminoacyl-tRNA synthetase-associated