Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Aminoacyl-transfer RNA synthetases class-II family profile
Signal transduction histidine kinase internal region
Tryptophan synthase beta chain-like PALP
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Alanyl-transfer RNA synthetases family profile
O-(5'-phospho-DNA)-tyrosine intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Translation elongation factor P/YeiP central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Small ribosomal subunit protein uS4 N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Major facilitator superfamily (MFS) profile
Peptide methionine sulphoxide reductase MsrA
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
General stress protein FMN-binding split barrel
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Large ribosomal subunit protein uL15/eL18
Sodium/calcium exchanger membrane region
Glycine cleavage T-protein C-terminal barrel
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Septum formation inhibitor MinC C-terminal
DNA mismatch repair proteins mutS family
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Resolvase/invertase-type recombinase catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Probable transposase IS891/IS1136/IS1341
Penicillin-binding protein transpeptidase
Chromosomal replication initiator DnaA C-terminal
Essential for prephenate dehydratase activity
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
RND efflux pump membrane fusion protein barrel-sandwich
Polymerase/histidinol phosphatase N-terminal
Polysaccharide biosynthesis protein CapD-like
Electron transfer flavoprotein alpha/beta-subunit N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
ATP-dependent DNA helicase RecG C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycosyltransferase subfamily 4-like N-terminal
Pseudouridine synthase I TruA alpha/beta
Alpha-D-phosphohexomutase alpha/beta/alpha
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Gly-cisPro motif, important for rejection of L-amino acids
Interaction with polymerase core subunit RpoC
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like stalk
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Required for zinc-mediated homotetramerization and catalytic activity
Polysaccharide biosynthesis protein C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-directed DNA polymerase family A palm
DNA replication/recombination mediator RecO N-terminal
Prepilin type IV endopeptidase peptidase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Inner membrane protein YgaP-like transmembrane
Solute-binding protein family 3/N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyl transferase family 3 N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Urease accessory protein UreH-like transmembrane
Carbamoyl-phosphate synthase small subunit N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
YbaK/aminoacyl-tRNA synthetase-associated
ssDNA thymidine ADP-ribosyltransferase DarT
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Thymidylate synthase/dCMP hydroxymethylase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Large ribosomal subunit protein uL2 C-terminal
Glycosyl transferase family 28 C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
TonB-dependent receptor-like beta-barrel
Cytochrome b561 bacterial/Ni-hydrogenase
Bacterial type II secretion system protein E
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Chromosomal replication initiator protein DnaA
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Type III restriction enzyme C-terminal endonuclease
Cysteine sulfenic acid (-SOH) intermediate
Exonuclease VII large subunit C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Type II secretion system protein GspI C-terminal
Type I restriction modification DNA specificity
Beta-lactamase hydrolase-like protein phosphatase-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Virulence factor membrane-bound polymerase C-terminal
NIF system FeS cluster assembly NifU C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Phosphoadenosine phosphosulphate reductase
Pyruvate dehydrogenase E1 component middle
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Gamma-glutamylcyclotransferase AIG2-like
Aminoacyl-tRNA synthetase class I anticodon-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NIF system FeS cluster assembly NifU N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA binding; important for wobble base 34 recognition
RNA 2-O ribose methyltransferase substrate binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Important for interaction with partner proteins
Plays an important role in substrate specificity
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Phosphatidic acid phosphatase type 2/haloperoxidase
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Disulphide bond isomerase DsbC/G N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
N-end rule aminoacyl transferase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Shikimate dehydrogenase substrate binding N-terminal
Glycosyltransferase family 28 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA adenine methylase transferase N-terminal
Prokaryotic-type class I peptide chain release factors
Interacts with tRNA; defines subfamily-specific binding signature
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glycosyltransferase 2-like prokaryotic type
UDP N-acetylglucosamine O-acyltransferase C-terminal
Outer membrane protein assembly factor BamA
Polysaccharide chain length determinant N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphoethanolamine transferase N-terminal
Ionotropic glutamate receptor C-terminal
Reversibly protonated during proton transport
Erythronate-4-phosphate dehydrogenase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Outer-membrane lipoprotein carrier protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for substrate binding and specificity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Could be important to modulate the pK values of the two catalytic cysteine residues
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic