ABC transporter substrate-binding protein
Glycosyl transferase family 3 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Schiff-base intermediate with substrate; via pyruvic acid
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Major facilitator superfamily (MFS) profile
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cytochrome b/b6 N-terminal region profile
SUF system FeS cluster assembly SufBD N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Thiopeptide-type bacteriocin biosynthesis
Probable transposase IS891/IS1136/IS1341
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Tryptophan synthase beta chain-like PALP
RNA polymerase sigma factor 70 region 4 type 2
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycosyl transferase family 28 C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
YbaK/aminoacyl-tRNA synthetase-associated
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Lipocalin-like domain-containing protein
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Phosphocysteine intermediate; for EIIB activity
Cytochrome oxidase subunit II copper A binding
Solute-binding protein family 3/N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Bacterial type II secretion system protein E
Fibronectin type-III domain-containing protein
Gram-positive cocci surface proteins LPxTG
Ribose-phosphate pyrophosphokinase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Dipicolinate synthase subunit A N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Thiamin pyrophosphokinase thiamin-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Involved in allosteric activation by GTP
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Intracellular proteinase inhibitor BsuPI
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Flagellar motor switch protein FliN-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Cytochrome b/b6 C-terminal region profile
Gamma-glutamylcyclotransferase AIG2-like
O-(3'-phospho-DNA)-tyrosine intermediate
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Moybdenum cofactor oxidoreductase dimerisation
Plays an important role in substrate specificity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Thymidylate synthase/dCMP hydroxymethylase
Cysteine sulfenic acid (-SOH) intermediate
Transcriptional regulator SgrR N-terminal HTH
Resolvase/invertase-type recombinase catalytic
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Alanyl-transfer RNA synthetases family profile
LysM peptidoglycan-binding domain-containing protein
Positions MEP for the nucleophilic attack
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Carbamoyl-phosphate synthase small subunit N-terminal
Transposase IS116/IS110/IS902 C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Proteinase inhibitor I42 chagasin domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Na+/H+ antiporter MnhB subunit-related protein
Glycosyltransferase family 28 N-terminal
Spore germination GerAC-like C-terminal domain-containing protein
Cell envelope-related transcriptional attenuator
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Glycine cleavage T-protein C-terminal barrel
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alpha-glycerophosphate oxidase C-terminal
Bacterial Ig-like domain-containing protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prokaryotic-type class I peptide chain release factors
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
DNA polymerase III delta subunit C-terminal
Pseudouridine synthase I TruA alpha/beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
ABC transporter substrate-binding protein PnrA-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Magnesium transporter MgtE intracellular
Menaquinone biosynthesis protein MenD middle
Peptidase M10 metallopeptidase domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NIF system FeS cluster assembly NifU N-terminal
Small ribosomal subunit protein uS4 N-terminal
Adaptive response protein AidB N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Flagellar basal-body/hook protein C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Alpha-D-phosphohexomutase alpha/beta/alpha
Could play a key role in the communication between the regulatory and the substrate sites
Peptide methionine sulphoxide reductase MsrA
Interaction with polymerase core subunit RpoC
Ionotropic glutamate receptor C-terminal
Sporulation initiation phosphotransferase B C-terminal
Threonine/serine exporter-like N-terminal
Putative aromatic acid exporter C-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Translation elongation factor P/YeiP central
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Polysaccharide biosynthesis protein CapD-like
Single-stranded-DNA-specific exonuclease RecJ C-terminal
RNA 2-O ribose methyltransferase substrate binding
SGNH hydrolase-type esterase domain-containing protein
Exonuclease VII large subunit C-terminal
Polysaccharide biosynthesis protein C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DnaJ homologue subfamily C member 28 conserved
Lysidine-tRNA(Ile) synthetase C-terminal
Release factor glutamine methyltransferase N-terminal
Cytochrome oxidase subunit II transmembrane region profile
Large ribosomal subunit protein uL15/eL18
Glycosyl hydrolase-like 10 domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Flagellar hook-length control protein-like C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Sugar ABC transporter substrate-binding protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Anthranilate synthase component I N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Divergent polysaccharide deacetylase family protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphotransferase system enzyme I N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
DNA replication/recombination mediator RecO N-terminal
LPXTG cell wall anchor domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Peptidase S8/S53 domain-containing protein
Tellurite resistance methyltransferase TehB-like
Polysaccharide chain length determinant N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Essential for prephenate dehydratase activity
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Heat-inducible transcription repressor HrcA C-terminal
Sporulation stage IV protein A C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Na+-translocating membrane potential-generating system MpsC
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Gram-positive cocci surface proteins LPxTG domain-containing protein
Flagellar assembly protein FliH/Type III secretion system HrpE
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Sporulation transcription regulator WhiA N-terminal
Polymerase/histidinol phosphatase N-terminal
RNA binding; important for wobble base 34 recognition
YhcN/YlaJ family sporulation lipoprotein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyridoxamine 5'-phosphate oxidase putative
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Tryptophan RNA-binding attenuator protein
Intracellular proteinase inhibitor BsuPI domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Cation-transporting P-type ATPase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Urease accessory protein UreH-like transmembrane
Cytochrome C biogenesis protein transmembrane
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ABC-type glycine betaine transport system substrate-binding
Lactate utilization protein B C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Lysozyme inhibitor LprI N-terminal domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Schiff-base intermediate with acetaldehyde
Pyrimidine nucleoside phosphorylase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Sodium/calcium exchanger membrane region
Important for interaction with partner proteins
DNA mismatch repair proteins mutS family
Sodium symporter small subunit predicted
Heme-copper oxidase subunit III family profile
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Reversibly protonated during proton transport
Type II secretion system protein GspE N-terminal
Peptidase C39-like domain-containing protein
N6 adenine-specific DNA methyltransferase N-terminal
tRNA pseudouridylate synthase B C-terminal
Ribonucleotide reductase large subunit C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA-directed DNA polymerase family A palm
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Chromosomal replication initiator DnaA C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Cycloisomaltooligosaccharide glucanotransferase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Superoxide dismutase copper/zinc binding
RND efflux pump membrane fusion protein barrel-sandwich
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity