UDP-glucose/GDP-mannose dehydrogenase C-terminal
FMN-dependent NADH:quinone oxidoreductase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Guanylate kinase/L-type calcium channel beta subunit
tRNA N6-adenosine threonylcarbamoyltransferase
Putative phosphoenolpyruvate synthase regulatory protein
Putative iron-sulfur cluster insertion protein ErpA
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Heat-inducible transcription repressor HrcA
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Periplasmic binding protein/LacI sugar binding
PEP-CTERM protein-sorting domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Probable nicotinate-nucleotide adenylyltransferase
Sec-independent protein translocase protein TatA
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Type I restriction modification DNA specificity
Penicillin-binding protein transpeptidase
Putative membrane protein insertion efficiency factor
Cytochrome b561 bacterial/Ni-hydrogenase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Phosphatidic acid phosphatase type 2/haloperoxidase
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC
Heme-copper oxidase subunit III family profile
TonB-dependent receptor-like beta-barrel
Bacterial type II secretion system protein E
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Gamma-butyrobetaine hydroxylase-like N-terminal
Major facilitator superfamily (MFS) profile
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
RNA polymerase sigma factor 70 region 4 type 2
Phosphoadenosine phosphosulphate reductase
High potential iron-sulfur proteins family profile
Membrane fusion protein biotin-lipoyl like
Proline utilization A proline dehydrogenase N-terminal
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Mannose-6-phosphate isomerase type II C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Probable transcriptional regulatory protein Rfer_2075
ABC transporter substrate-binding protein
Phosphoribosylaminoimidazole-succinocarboxamide synthase
MtrB/PioB family decaheme-associated outer membrane protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyl transferase family 3 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Gly-cisPro motif, important for rejection of L-amino acids
Adaptive response protein AidB N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Aliphatic sulfonates import ATP-binding protein SsuB
Plays an important role in substrate specificity
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Doubled CXXCH motif domain-containing protein
Cytochrome C biogenesis protein transmembrane
Interacts with tRNA; defines subfamily-specific binding signature
CobB/CobQ-like glutamine amidotransferase
Sodium/calcium exchanger membrane region
2-dehydro-3-deoxyphosphooctonate aldolase
Anthranilate synthase component I N-terminal
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Tryptophan synthase beta chain-like PALP
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Prepilin type IV endopeptidase peptidase
Abortive infection protein-like C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Transcription regulator AsnC/Lrp ligand binding
Cytochrome c-type biogenesis protein CcmF C-terminal
NIF system FeS cluster assembly NifU N-terminal
Methionine import ATP-binding protein MetN
Urease accessory protein UreH-like transmembrane
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Butirosin biosynthesis protein H N-terminal
Holliday junction branch migration complex subunit RuvB
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polysaccharide biosynthesis protein CapD-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Histidine-specific methyltransferase SAM-dependent
3-isopropylmalate dehydratase small subunit
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Release factor glutamine methyltransferase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
PHA accumulation regulator DNA-binding N-terminal
ATP-dependent Clp protease adapter protein ClpS
Pyruvate phosphate dikinase AMP/ATP-binding
Isocitrate dehydrogenase kinase/phosphatase
Transcription antitermination protein NusB
Cyclic pyranopterin monophosphate synthase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
NADH:ubiquinone oxidoreductase 30kDa subunit
Crossover junction endodeoxyribonuclease RuvC
Mandelate racemase/muconate lactonizing enzyme C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Pyruvate dehydrogenase E1 component middle
DNA-directed RNA polymerase subunit omega
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cation-transporting P-type ATPase N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glutamate-1-semialdehyde 2,1-aminomutase
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Pyridoxamine 5'-phosphate oxidase putative
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Polysaccharide chain length determinant N-terminal
FAD-dependent oxidoreductase 2 FAD binding
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Glycosyltransferase subfamily 4-like N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
ABC transporter substrate-binding protein PnrA-like
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Polyribonucleotide nucleotidyltransferase
Toxin co-regulated pilus biosynthesis protein Q C-terminal
Toxin co-regulated pilus biosynthesis protein Q C-terminal domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Signal transduction histidine kinase internal region
Formate-dependent phosphoribosylglycinamide formyltransferase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
3-methyl-2-oxobutanoate hydroxymethyltransferase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphonates import ATP-binding protein PhnC 1
Transposase IS116/IS110/IS902 C-terminal
Cytochrome oxidase subunit II copper A binding
Glutamyl-tRNA(Gln) amidotransferase subunit A
Sec-independent protein translocase protein TatB
Outer-membrane lipoprotein carrier protein
Flagellar motor switch protein FliN-like C-terminal
Putative regulatory protein FmdB Zinc ribbon
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
D-(-)-3-hydroxybutyrate oligomer hydrolase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
4-hydroxy-tetrahydrodipicolinate synthase
ATP phosphoribosyltransferase regulatory subunit
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Dual-specificity RNA methyltransferase RlmN
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Type II secretion system protein GspI C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Prokaryotic-type class I peptide chain release factors
PhoD-like phosphatase metallophosphatase
Proton acceptor; for glutaminase activity
Phenylalanine--tRNA ligase alpha subunit
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Schiff-base intermediate with substrate; via pyruvic acid
Important for interaction with partner proteins
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
S-adenosyl-L-homocysteine hydrolase NAD binding
Putative Flp pilus-assembly TadG-like N-terminal
ABC-type transport auxiliary lipoprotein component
DNA polymerase III subunit delta C-terminal
Ribosomal RNA small subunit methyltransferase A
Phosphoribosylformylglycinamidine cyclo-ligase
Antitoxin Xre/MbcA/ParS-like toxin-binding
TIGR03016 family PEP-CTERM system-associated outer membrane protein
Pyrimidine/purine nucleoside phosphorylase
RNA binding; important for wobble base 34 recognition
Translocation and assembly module subunit TamA
ATP-dependent Clp protease ATP-binding subunit ClpX
Sodium symporter small subunit predicted
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Essential for prephenate dehydratase activity
Bacterial bifunctional deaminase-reductase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Reversibly protonated during proton transport
Solute-binding protein family 3/N-terminal domain-containing protein
EfeO-type cupredoxin-like domain-containing protein
Phosphotransferase system enzyme I N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ribosomal RNA small subunit methyltransferase G
Involved in Mg(2+) ion dislocation from EF-Tu
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
YbaK/aminoacyl-tRNA synthetase-associated
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Probable 2-(5""-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Imidazole glycerol phosphate synthase subunit HisF
Important for substrate specificity; cannot use PPi as phosphoryl donor
6-phosphogluconate dehydrogenase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Iron-sulfur cluster assembly protein CyaY
Interaction with polymerase core subunit RpoC
Important for beta-aspartyl-AMP intermediate formation
Cytochrome c7-like domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Holliday junction branch migration complex subunit RuvA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Thioredoxin-like fold domain-containing protein
3-deoxy-manno-octulosonate cytidylyltransferase
Leucyl/phenylalanyl-tRNA--protein transferase
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Adenosylcobinamide-GDP ribazoletransferase
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
DNA-directed DNA polymerase family A palm
Flagellar hook-length control protein-like C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Ribosomal RNA large subunit methyltransferase H
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Nucleophile; cysteine thiosulfonate intermediate
Ribose-phosphate pyrophosphokinase N-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Leucine-binding protein domain-containing protein
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Cytochrome c-552/DMSO reductase-like haem-binding
Chromosomal replication initiator DnaA C-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Poly-beta-hydroxybutyrate polymerase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
DNA-directed RNA polymerase subunit beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Succinate--CoA ligase [ADP-forming] subunit beta
O-(3'-phospho-DNA)-tyrosine intermediate
Peptide methionine sulphoxide reductase MsrA
DNA-directed RNA polymerase subunit beta'
Cell division topological specificity factor
Protein-glutamate methylesterase/protein-glutamine glutaminase 2
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Glycosyl transferase family 28 C-terminal
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
NfeD-like C-terminal domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Helix-hairpin-helix domain-containing protein
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Aldehyde ferredoxin oxidoreductase N-terminal
Phosphonates import ATP-binding protein PhnC 2
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Chromosomal replication initiator protein DnaA
Outer membrane protein assembly factor BamD
ParB-related ThiF-related cassette protein E
Inner membrane protein YgaP-like transmembrane
Type 4 fimbrial biogenesis protein PilX N-terminal
UDP-3-O-acylglucosamine N-acyltransferase
Probable potassium transport system protein Kup 2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Gfo/Idh/MocA-like oxidoreductase C-terminal
ATP-dependent Clp protease proteolytic subunit
Phosphate import ATP-binding protein PstB
Ribosomal protein uS12 methylthiotransferase RimO
Polysaccharide biosynthesis protein C-terminal
S-adenosylmethionine-dependent methyltransferase
Molybdenum import ATP-binding protein ModC
Required for zinc-mediated homotetramerization and catalytic activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
RNA 2-O ribose methyltransferase substrate binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Putative ribose/galactose/methyl galactoside import ATP-binding protein
Cytochrome c-552/4 domain-containing protein
Lipoprotein-releasing system ATP-binding protein LolD
Activator of Hsp90 ATPase homologue 1-like C-terminal
Virulence factor membrane-bound polymerase C-terminal
Ribosomal RNA large subunit methyltransferase E
DNA-directed RNA polymerase subunit alpha
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase
CNP1-like uncharacterized domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Type II secretion system protein GspC N-terminal domain-containing protein
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein