Alpha-D-phosphohexomutase alpha/beta/alpha
Prokaryotic-type class I peptide chain release factors
Plays an important role in substrate specificity
Thymidylate synthase/dCMP hydroxymethylase
RNA polymerase sigma factor 70 region 4 type 2
Translation elongation factor P/YeiP central
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pseudouridine synthase I TruA alpha/beta
Choloylglycine hydrolase/NAAA C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Major facilitator superfamily (MFS) profile
High-affinity zinc uptake system protein ZnuA
Major facilitator superfamily associated
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
RNA binding; important for wobble base 34 recognition
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptide methionine sulphoxide reductase MsrA
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL25 L25
Outer membrane protein assembly factor BamE
Positions MEP for the nucleophilic attack
Proton acceptor; for glutaminase activity
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
SUF system FeS cluster assembly SufBD N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
O-(3'-phospho-DNA)-tyrosine intermediate
Tryptophan synthase beta chain-like PALP
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Penicillin-binding protein activator LpoB
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Flagellar motor switch protein FliN N-terminal
Flagellar motor switch protein FliN-like C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Shikimate dehydrogenase substrate binding N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Gfo/Idh/MocA-like oxidoreductase C-terminal
ABC transporter substrate-binding protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Phosphoadenosine phosphosulphate reductase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
ATP synthase F1 complex delta/epsilon subunit N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL6 alpha-beta
ABC-type glycine betaine transport system substrate-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Outer membrane protein assembly factor BamD
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
L,D-transpeptidase catalytic domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RND efflux pump membrane fusion protein barrel-sandwich
Non-canonical purine NTP phosphatase/PRRC1
Outer-membrane lipoprotein carrier protein
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Flagella basal body P-ring formation protein FlgA
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Plays an important role in discriminating NADH against NADPH
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Involved in allosteric activation by GTP
Pyruvate dehydrogenase E1 component middle
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Translocation and assembly module subunit TamA
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Interaction with polymerase core subunit RpoC
Ion-translocating oxidoreductase complex subunit G
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Schiff-base intermediate with acetaldehyde
NIF system FeS cluster assembly NifU N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Chromosomal replication initiator DnaA C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH:ubiquinone oxidoreductase 30kDa subunit
Essential for degradation by Lon protease
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
DNA replication/recombination mediator RecO N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tetrahydrodipicolinate-N-succinyltransferase chain A
Fels-1 Propage domain-containing protein
Phosphocysteine intermediate; for EIIB activity
NIF system FeS cluster assembly NifU C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
RNA 2-O ribose methyltransferase substrate binding
Quercetin 2,3-dioxygenase C-terminal cupin
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Chromosomal replication initiator protein DnaA
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
L-seryl-tRNA selenium transferase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Small ribosomal subunit protein uS4 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Disulphide bond isomerase DsbC/G N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Reversibly protonated during proton transport
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Regulator of nucleoside diphosphate kinase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Arginine decarboxylase C-terminal helical
HicB-like antitoxin of toxin-antitoxin system
Periplasmic nitrate reductase, electron transfer subunit
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Membrane insertase YidC/Oxa/ALB C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Moves into active site upon enzyme activation, plays a role in electron transfer
PapG chaperone-binding domain-containing protein