Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Flagellar assembly protein FliH/Type III secretion system HrpE
Survival protein SurE-like phosphatase/nucleotidase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cytochrome b561 bacterial/Ni-hydrogenase
Type II secretion system protein GspC N-terminal
Tryptophan synthase beta chain-like PALP
TRAP C4-dicarboxylate transport system permease DctM subunit
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alpha-D-phosphohexomutase alpha/beta/alpha
High potential iron-sulfur proteins family profile
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Virulence factor membrane-bound polymerase C-terminal
CobB/CobQ-like glutamine amidotransferase
Bacterial type II secretion system protein E
Solute-binding protein family 3/N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Polymerase/histidinol phosphatase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Plays an important role in substrate specificity
Ribose-phosphate pyrophosphokinase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Ionotropic glutamate receptor C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Glycosyl transferase family 3 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
N-end rule aminoacyl transferase C-terminal
Release factor glutamine methyltransferase N-terminal
Membrane fusion protein biotin-lipoyl like
Alanyl-transfer RNA synthetases family profile
Sodium/calcium exchanger membrane region
Major facilitator superfamily (MFS) profile
S-adenosyl-L-homocysteine hydrolase NAD binding
Sodium symporter small subunit predicted
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome c-type biogenesis protein CcmF C-terminal
Phosphoadenosine phosphosulphate reductase
TIGR03016 family PEP-CTERM system-associated outer membrane protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Important for beta-aspartyl-AMP intermediate formation
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar motor switch protein FliN-like C-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Proline utilization A proline dehydrogenase N-terminal
Prokaryotic-type class I peptide chain release factors
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycine cleavage T-protein C-terminal barrel
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
PEP-CTERM protein-sorting domain-containing protein
Transglycosylase SLT domain-containing protein
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Signal transduction histidine kinase internal region
Reversibly protonated during proton transport
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
O-(5'-phospho-DNA)-tyrosine intermediate
ABC-type transport auxiliary lipoprotein component
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
DNA replication/recombination mediator RecO N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Sel1 domain protein repeat-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Disulphide bond isomerase DsbC/G N-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Polysaccharide chain length determinant N-terminal
Thiol:disulfide interchange protein DsbD
Gly-cisPro motif, important for rejection of L-amino acids
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Anthranilate synthase component I N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Small ribosomal subunit protein uS4 N-terminal
ABC transporter substrate-binding protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Prepilin type IV endopeptidase peptidase
Signal transduction histidine kinase dimerisation/phosphoacceptor
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Mandelate racemase/muconate lactonizing enzyme C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Mannose-6-phosphate isomerase type II C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Polypeptide-transport-associated ShlB-type
Polypeptide-transport-associated ShlB-type domain-containing protein
Solute-binding protein family 5 domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Translocation and assembly module subunit TamA
Urease accessory protein UreH-like transmembrane
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Nitrite/Sulfite reductase ferredoxin-like
Solute-binding protein family 3/N-terminal domain-containing protein
ATP-dependent DNA helicase RecG C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Sugar fermentation stimulation protein C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Metal ABC transporter substrate-binding protein
Ribonucleotide reductase large subunit C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Exonuclease VII large subunit C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RND efflux pump membrane fusion protein barrel-sandwich
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Positions MEP for the nucleophilic attack
Alpha-glycerophosphate oxidase C-terminal
Interaction with polymerase core subunit RpoC
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Na+/H+ antiporter MnhB subunit-related protein
Outer membrane protein assembly factor BamA
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Electron transfer flavoprotein alpha subunit C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Beta-lactamase hydrolase-like protein phosphatase-like
Helix-hairpin-helix DNA-binding motif class 1
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
ABC-type glycine betaine transport system substrate-binding
Electron transfer via tryptophanyl radical
Phosphatidic acid phosphatase type 2/haloperoxidase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glucosamine/galactosamine-6-phosphate isomerase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Chromosomal replication initiator DnaA C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Type II secretion system protein GspI C-terminal
Chromosomal replication initiator protein DnaA
Saccharopine dehydrogenase-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Essential for prephenate dehydratase activity
Gfo/Idh/MocA-like oxidoreductase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Important for interaction with partner proteins
Shikimate dehydrogenase substrate binding N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Proton acceptor; for glutaminase activity
Flagella basal body P-ring formation protein FlgA
DNA polymerase III subunit delta C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Oxidoreductase molybdopterin-binding domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
TonB-dependent receptor-like beta-barrel
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Inner membrane protein YgaP-like transmembrane
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Translation elongation factor P/YeiP central
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
CASTOR/POLLUX/SYM8 ion channel conserved
4'-phosphopantetheinyl transferase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Organic solvent tolerance-like N-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL2 C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
S-adenosylmethionine-dependent methyltransferase
Resolvase/invertase-type recombinase catalytic
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NIF system FeS cluster assembly NifU C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glucose-methanol-choline oxidoreductase N-terminal
DNA mismatch repair proteins mutS family
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pseudouridine synthase I TruA alpha/beta
Erythronate-4-phosphate dehydrogenase dimerisation
Flagellar hook-length control protein-like C-terminal
Heme-copper oxidase subunit III family profile
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Type II secretion system protein GspG C-terminal
Outer-membrane lipoprotein carrier protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
UDP N-acetylglucosamine O-acyltransferase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA-directed DNA polymerase family A palm
Cation-transporting P-type ATPase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Required for zinc-mediated homotetramerization and catalytic activity
Outer membrane protein assembly factor BamD
Outer membrane lipoprotein-sorting protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Glutamine ABC transporter substrate-bindnig protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Putative regulatory protein FmdB Zinc ribbon
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL15/eL18
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Peptide methionine sulphoxide reductase MsrA
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-97)
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transcription elongation factor GreA/GreB N-terminal
BREX system Lon protease-like BrxL N-terminal
Involved in allosteric activation by GTP
Sec translocon accessory complex subunit YajC