Ribose-phosphate pyrophosphokinase N-terminal
Prokaryotic-type class I peptide chain release factors
Penicillin-binding protein transpeptidase
YbaK/aminoacyl-tRNA synthetase-associated
Serine-aspartate repeat-containing protein D
Chromosomal replication initiator DnaA C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Helix-hairpin-helix DNA-binding motif class 1
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL6 alpha-beta
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL15/eL18
Lysidine-tRNA(Ile) synthetase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Endo-alpha-N-acetylgalactosaminidase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
ABC transporter substrate-binding protein PnrA-like
Resolvase/invertase-type recombinase catalytic
Cytochrome C biogenesis protein transmembrane
Phosphoribosylformylglycinamidine synthase linker
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Solute-binding protein family 3/N-terminal
CobB/CobQ-like glutamine amidotransferase
Signal transduction histidine kinase internal region
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Ribosomal RNA adenine methylase transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
AraC-type arabinose-binding/dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Could play a key role in the communication between the regulatory and the substrate sites
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphomannose isomerase type I catalytic
Large ribosomal subunit protein bL9 C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
tRNA pseudouridylate synthase B C-terminal
Prepilin type IV endopeptidase peptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Type III restriction enzyme C-terminal endonuclease
Schiff-base intermediate with substrate; via pyruvic acid
RNA 2-O ribose methyltransferase substrate binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
CD-NTase associated protein 4-like DNA endonuclease
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
6-phosphogluconate dehydrogenase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phosphatidylglycerol lysyltransferase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alpha-D-phosphohexomutase alpha/beta/alpha
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptide methionine sulphoxide reductase MsrA
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Cell envelope-related transcriptional attenuator
DNA replication/recombination mediator RecO N-terminal
Cation-transporting P-type ATPase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Gly-cisPro motif, important for rejection of L-amino acids
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Alanyl-transfer RNA synthetases family profile
Fatty acid kinase subunit A-like C-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Phosphocysteine intermediate; for EIIB activity
Sporulation transcription regulator WhiA N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyrimidine nucleoside phosphorylase C-terminal
Lacto-N-biose phosphorylase-like N-terminal TIM barrel
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA polymerase sigma factor 70 region 4 type 2
Glutathionylspermidine synthase pre-ATP-grasp-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Major facilitator superfamily (MFS) profile
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Bacterial type II secretion system protein E
Type I restriction modification DNA specificity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Exonuclease VII large subunit C-terminal
Polymerase/histidinol phosphatase N-terminal
Polysaccharide chain length determinant N-terminal
Type I restriction enzyme R protein N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
NIF system FeS cluster assembly NifU N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL2 C-terminal
Polysaccharide biosynthesis protein CapD-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Gram-positive cocci surface proteins LPxTG
Gram-positive pilin backbone subunit 2 Cna-B-like
Gram-positive pilin backbone subunit 3 Cna-B-like
Gram-positive pilin subunit D1 N-terminal
Thiamin pyrophosphokinase thiamin-binding
RNA binding; important for wobble base 34 recognition
Pseudouridine synthase I TruA alpha/beta
Small ribosomal subunit protein uS4 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycoside hydrolase family 13 N-terminal
Threonine/serine exporter-like N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA mismatch repair proteins mutS family
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
ATP-dependent DNA helicase RecG C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Schiff-base intermediate with acetaldehyde
Peptidase S9 prolyl oligopeptidase catalytic
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Transcriptional coactivator p15 (PC4) C-terminal
Phosphotransferase system enzyme I N-terminal
DNA-directed DNA polymerase family A palm
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding