Major facilitator superfamily (MFS) profile
Essential for prephenate dehydratase activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Helix-hairpin-helix DNA-binding motif class 1
Gp5/Type VI secretion system Vgr protein OB-fold
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Peptidase M6-like domain-containing protein
Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
Glucosamine/galactosamine-6-phosphate isomerase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NIF system FeS cluster assembly NifU N-terminal
Glycosyltransferase subfamily 4-like N-terminal
CRISPR-associated protein Cas6 C-terminal
CRISPR-associated protein Cas6 C-terminal domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Cell envelope-related transcriptional attenuator
K(+)-insensitive pyrophosphate-energized proton pump
Shikimate dehydrogenase substrate binding N-terminal
Electron transfer via tryptophanyl radical
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Aspartate/homoserine dehydrogenase NAD-binding
Fibronectin type-III domain-containing protein
Penicillin-binding protein transpeptidase
Glycoside hydrolase family 31 N-terminal
Membrane fusion protein biotin-lipoyl like
Aconitase A/isopropylmalate dehydratase small subunit swivel
SUF system FeS cluster assembly SufBD N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Peptidase MA-like domain-containing protein
Magnesium chelatase subunit H N-terminal
Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase
DNA-directed RNA polymerase subunit beta'
Succinate--CoA ligase [ADP-forming] subunit beta
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Glutamate-1-semialdehyde 2,1-aminomutase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Alpha-D-phosphohexomutase alpha/beta/alpha
RNA binding; important for wobble base 34 recognition
Probable inorganic carbon transporter subunit DabA
Imidazole glycerol phosphate synthase subunit HisF
Ribose-phosphate pyrophosphokinase N-terminal
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
RNA polymerase sigma factor 70 region 4 type 2
Formylmethanofuran dehydrogenase subunit E
6-phosphogluconate dehydrogenase C-terminal
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Phosphotransferase system enzyme I N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Peptide methionine sulphoxide reductase MsrA
Glycoside hydrolase family 5 domain-containing protein
Important for interaction with partner proteins
Sec-independent protein translocase protein TatA
Peptidase S9 prolyl oligopeptidase catalytic
Polysaccharide chain length determinant N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Sodium/calcium exchanger membrane region
Gamma-glutamylcyclotransferase AIG2-like
Homogentisate 1,2-dioxygenase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Phosphomannose isomerase type I catalytic
Could play a key role in the communication between the regulatory and the substrate sites
FAD-dependent oxidoreductase 2 FAD binding
DNA mismatch repair proteins mutS family
Aminoacyl-transfer RNA synthetases class-II family profile
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Carbohydrate-binding domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Uncharacterized sensor-like histidine kinase Caur_0899
CRISPR-associated endoribonuclease Cas2 3
Pyruvate phosphate dikinase AMP/ATP-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Survival protein SurE-like phosphatase/nucleotidase
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
L-seryl-tRNA selenium transferase N-terminal
Tryptophan synthase beta chain-like PALP
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
CRISPR-associated endoribonuclease Cas2 1
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Polysaccharide biosynthesis protein C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Plays an important role in substrate specificity
Adaptive response protein AidB N-terminal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Polysaccharide biosynthesis protein CapD-like
Light-harvesting protein B-808/866 beta chain
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Uncharacterized RNA pseudouridine synthase Caur_0901
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Putative pyruvate, phosphate dikinase regulatory protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Glutamyl-tRNA(Gln) amidotransferase subunit A
Ribosomal RNA small subunit methyltransferase G
Sugar fermentation stimulation protein homolog
3-methyl-2-oxobutanoate hydroxymethyltransferase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cytochrome c-type biogenesis protein CcmF C-terminal
CRISPR-associated endoribonuclease Cas2 2
Ribosomal RNA adenine methylase transferase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Reversibly protonated during proton transport
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
3-keto-disaccharide hydrolase domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Interaction with polymerase core subunit RpoC
Exonuclease VII large subunit C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alanyl-transfer RNA synthetases family profile
RND efflux pump membrane fusion protein barrel-sandwich
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
UPF0173 metal-dependent hydrolase Caur_2542
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Light-harvesting protein B-808/866 alpha chain
Myo-inositol-1-phosphate synthase GAPDH-like
ABC transporter substrate-binding protein PnrA-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
CobB/CobQ-like glutamine amidotransferase
Iron dependent repressor metal binding and dimerisation
Chromosomal replication initiator protein DnaA
Glycoamylase-like domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Succinyl-CoA--L-malate CoA-transferase alpha subunit
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Bacterial type II secretion system protein E
Thiamin pyrophosphokinase thiamin-binding
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Magnesium-protoporphyrin IX methyltransferase C-terminal
Tellurite resistance methyltransferase TehB-like
Alpha-L-rhamnosidase six-hairpin glycosidase
NADH:ubiquinone oxidoreductase chain 4 N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Electron transfer flavoprotein alpha/beta-subunit N-terminal
EfeO-type cupredoxin-like domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Co-chaperone DjlA N-terminal domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Sodium symporter small subunit predicted
Aldehyde ferredoxin oxidoreductase N-terminal
Forms an intersubunit disulfide bridge, which makes the enzyme more resistant to thermal denaturation. The mutation does not alter the quaternary structure of the enzyme.
TRAP-T family transporter, periplasmic binding protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Imidazole glycerol phosphate synthase subunit HisH
Pyridoxamine 5'-phosphate oxidase putative
RlpA-like protein double-psi beta-barrel
Carboxypeptidase regulatory-like domain-containing protein
3-phosphoshikimate 1-carboxyvinyltransferase
Cytochrome C biogenesis protein transmembrane
Capsule synthesis protein CapA domain-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Redox-sensing transcriptional repressor Rex
Phosphatidylglycerol lysyltransferase C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Holliday junction branch migration complex subunit RuvB
Signal recognition particle SRP54 helical bundle
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Biopterin-dependent aromatic amino acid hydroxylase family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
O-(5'-phospho-DNA)-tyrosine intermediate
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Lysidine-tRNA(Ile) synthetase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Riboflavin transport system permease protein RibX
Type VII secretion system protein EssD-like
Subtilisin-like protease fibronectin type-III
Ribosomal RNA small subunit methyltransferase H
Na+/H+ antiporter MnhB subunit-related protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Light-independent protochlorophyllide reductase subunit N
Large-conductance mechanosensitive channel
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Putative pterin-4-alpha-carbinolamine dehydratase
3-isopropylmalate dehydratase small subunit
Release factor glutamine methyltransferase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Anthranilate synthase component I N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Cell division topological specificity factor
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridoxal 5'-phosphate synthase subunit PdxT
Phosphoribosylformylglycinamidine synthase linker
Type I restriction modification DNA specificity
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Holliday junction branch migration complex subunit RuvA
Inosine/uridine-preferring nucleoside hydrolase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Carbohydrate binding module xylan-binding
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Light-independent protochlorophyllide reductase subunit B
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein bL25 L25
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
RNA polymerase sigma factor 70 region 1.1
Succinyl-CoA--L-malate CoA-transferase beta subunit
Resolvase/invertase-type recombinase catalytic
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Phosphoribosylaminoimidazole-succinocarboxamide synthase
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Nitrite/Sulfite reductase ferredoxin-like
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Alpha-galactosidase NEW3 domain-containing protein
Uncharacterized DapA-like lyase Caur_1967
Ribosomal protein uS12 methylthiotransferase RimO
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Inner membrane protein YgaP-like transmembrane
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Increases nucleophilicity of active site Cys
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Crossover junction endodeoxyribonuclease RuvC
Bacterial alpha-L-rhamnosidase N-terminal
Heme-copper oxidase subunit III family profile
Important for substrate specificity; cannot use PPi as phosphoryl donor
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Succinyl-CoA--D-citramalate CoA-transferase
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Beta-lactamase class A catalytic domain-containing protein
Glycosyltransferase family 28 N-terminal
DNA-directed RNA polymerase subunit beta
Probable dual-specificity RNA methyltransferase RlmN
Proton acceptor; for glutaminase activity
Cyclic pyranopterin monophosphate synthase
Methylguanine DNA methyltransferase ribonuclease-like
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cation-transporting P-type ATPase N-terminal
Probable transcriptional regulatory protein Caur_1043
UDP-N-acetylenolpyruvoylglucosamine reductase
O-(3'-phospho-DNA)-tyrosine intermediate
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Heat-inducible transcription repressor HrcA
Polyribonucleotide nucleotidyltransferase
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Putative membrane protein insertion efficiency factor