Cytochrome oxidase subunit II copper A binding
FAD-dependent oxidoreductase 2 FAD binding
Cytochrome c biogenesis protein, transmembrane region
Peptidase S9 prolyl oligopeptidase catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Polymerase/histidinol phosphatase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
RND efflux pump membrane fusion protein barrel-sandwich
TRAP C4-dicarboxylate transport system permease DctM subunit
Dinitrogenase iron-molybdenum cofactor biosynthesis
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
tRNA N6-adenosine threonylcarbamoyltransferase
Zinc-regulated TonB-dependent outer membrane receptor
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Imidazole glycerol phosphate synthase subunit HisH
TonB-dependent receptor-like beta-barrel
Release factor glutamine methyltransferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Chromosomal replication initiator protein DnaA
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Fatty acid oxidation complex subunit alpha
For 3-hydroxyacyl-CoA dehydrogenase activity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Outer membrane protein beta-barrel domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Major facilitator superfamily (MFS) profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Penicillin-binding protein transpeptidase
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Heme-copper oxidase subunit III family profile
Deoxyguanosinetriphosphate triphosphohydrolase-like protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Solute-binding protein family 3/N-terminal
3-methyl-2-oxobutanoate hydroxymethyltransferase
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Flagellar Assembly Protein A N-terminal region
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Small-conductance mechanosensitive channel
Signal recognition particle SRP54 helical bundle
Leucyl/phenylalanyl-tRNA--protein transferase
Phosphoribosylformylglycinamidine cyclo-ligase
O-(3'-phospho-DNA)-tyrosine intermediate
YbaK/aminoacyl-tRNA synthetase-associated
Aspartate/homoserine dehydrogenase NAD-binding
Type II secretion system protein GspG C-terminal
Interaction with polymerase core subunit RpoC
Gamma-butyrobetaine hydroxylase-like N-terminal
DNA polymerase III subunit delta C-terminal
Putative phosphoenolpyruvate synthase regulatory protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycosyl-hydrolase 97 C-terminal oligomerisation
Peptidase M1 membrane alanine aminopeptidase
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
S-adenosylmethionine-dependent methyltransferase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Sulfite reductase [NADPH] hemoprotein beta-component
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Involved in allosteric activation by GTP
Ion-translocating oxidoreductase complex subunit E
Bacterial virulence factor lipase N-terminal
Polysaccharide chain length determinant N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
RNA 2-O ribose methyltransferase substrate binding
Peptidase M43 pregnancy-associated plasma-A
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
4-hydroxy-tetrahydrodipicolinate reductase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Threonine/serine exporter-like N-terminal
Ionotropic glutamate receptor C-terminal
Prokaryotic-type class I peptide chain release factors
Phosphatidic acid phosphatase type 2/haloperoxidase
Organic solvent tolerance-like N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Bacterial type II secretion system protein E
Tryptophan synthase beta chain-like PALP
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Conserved virulence factor B-like winged helix
Plays an important role in substrate specificity
N-end rule aminoacyl transferase C-terminal
EcxA zinc-binding domain-containing protein
Type 4 fimbrial biogenesis protein PilX N-terminal
Transposase IS116/IS110/IS902 C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
YcgL domain-containing protein Shew_2183
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
3-phosphoshikimate 1-carboxyvinyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Sugar fermentation stimulation protein homolog
Membrane fusion protein biotin-lipoyl like
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
ATP-dependent Clp protease adapter protein ClpS
Ribosomal RNA small subunit methyltransferase G
Alginate export domain-containing protein
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
O-(5'-phospho-DNA)-tyrosine intermediate
Glycosyl hydrolase family 98 putative carbohydrate-binding module
C-type lysozyme inhibitor domain-containing protein
Ribosomal RNA small subunit methyltransferase C
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Membrane-bound lytic murein transglycosylase F
Thiol:disulfide interchange protein DsbD
Imidazole glycerol phosphate synthase subunit HisF
Succinate--CoA ligase [ADP-forming] subunit beta
Cytochrome oxidase subunit II transmembrane region profile
Dual-specificity RNA methyltransferase RlmN
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Bacterial surface antigen (D15) domain-containing protein
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC
3-isopropylmalate dehydratase large subunit
Ion-translocating oxidoreductase complex subunit G
Phosphoethanolamine transferase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Deoxyuridine 5'-triphosphate nucleotidohydrolase
nitrite reductase (cytochrome; ammonia-forming)
ATP-dependent Clp protease proteolytic subunit
Carboxy-S-adenosyl-L-methionine synthase
Ribosomal RNA large subunit methyltransferase H
Na(+)-translocating NADH-quinone reductase subunit D
Type III secretion system flagellar brake protein YcgR PilZN
Acyl-CoA dehydrogenase C-terminal bacterial-type
6-hydroxymethylpterin diphosphokinase MptE-like
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Putative pterin-4-alpha-carbinolamine dehydratase
Proline utilization A proline dehydrogenase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribosomal RNA small subunit methyltransferase H
Polysaccharide biosynthesis protein CapD-like
Transglycosylase SLT domain-containing protein
tRNA/tmRNA (uracil-C(5))-methyltransferase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Ion-translocating oxidoreductase complex subunit B
Right handed beta helix domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Type II secretion system protein GspI C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Crossover junction endodeoxyribonuclease RuvC
Ribosomal RNA large subunit methyltransferase M
Cell division topological specificity factor
Iron-sulfur cluster insertion protein ErpA
Choloylglycine hydrolase/NAAA C-terminal
Sodium/calcium exchanger membrane region
Ribosomal RNA small subunit methyltransferase F
Ion-translocating oxidoreductase complex subunit D
Mandelate racemase/muconate lactonizing enzyme C-terminal
Schiff-base intermediate with acetaldehyde
3-isopropylmalate dehydratase small subunit
DNA replication/recombination mediator RecO N-terminal
Formate-dependent nitrite reductase complex subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transcription antitermination protein NusB
Tetrahaem cytochrome domain-containing protein
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Purine nucleoside phosphorylase DeoD-type
Solute-binding protein family 3/N-terminal domain-containing protein
Outer membrane protein assembly factor BamA
Ion-translocating oxidoreductase complex subunit A
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
UDP N-acetylglucosamine O-acyltransferase C-terminal
Holliday junction branch migration complex subunit RuvA
Transposon Tn7 transposition protein TnsD C-terminal
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Ribosomal RNA large subunit methyltransferase E
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA-directed RNA polymerase subunit beta'
Required for zinc-mediated homotetramerization and catalytic activity
Flagellar motor switch protein FliN-like C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Ysc84 actin-binding domain-containing protein
Resolvase/invertase-type recombinase catalytic
Interacts with tRNA; defines subfamily-specific binding signature
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Sec-independent protein translocase protein TatB
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Bacterial transcription activator effector binding
Enoyl-[acyl-carrier-protein] reductase [NADH]
Plays an important role in discriminating NADH against NADPH
Disulphide bond isomerase DsbC/G N-terminal
Subtilisin-like protease fibronectin type-III
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Pyruvate dehydrogenase E1 component middle
ATP-dependent Clp protease ATP-binding subunit ClpX
Inosine/uridine-preferring nucleoside hydrolase
RNA binding; important for wobble base 34 recognition
Amidohydrolase-related domain-containing protein
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Flagellar motor switch protein FliN N-terminal
Flagellar motor switch protein FliN N-terminal domain-containing protein
Polyribonucleotide nucleotidyltransferase
ATP-dependent DNA helicase RecG C-terminal
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase
Chalcone isomerase domain-containing protein
Chaperone for general secretion pathway YbaY
Prepilin type IV endopeptidase peptidase
Urease accessory protein UreH-like transmembrane
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Signal transduction histidine kinase internal region
Ribosomal RNA large subunit methyltransferase K/L
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
Fatty acid synthase subunit PfaD N-terminal
6-phosphogluconate dehydrogenase C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Protein-L-isoaspartate O-methyltransferase
Chitobiase/beta-hexosaminidases N-terminal
Type II secretion system protein GspC N-terminal
Glutamate-1-semialdehyde 2,1-aminomutase
Outer membrane protein assembly factor BamB
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Dipeptidyl-peptidase 7. Serine peptidase. MEROPS family S46
Curli production assembly/transport component CsgG
Inner membrane protein YgaP-like transmembrane
Important for beta-aspartyl-AMP intermediate formation
RNA polymerase sigma factor 70 region 4 type 2
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Could play a key role in the communication between the regulatory and the substrate sites
Mechanosensitive ion channel inner membrane
Outer-membrane lipoprotein carrier protein
2-dehydro-3-deoxyphosphooctonate aldolase
Holliday junction branch migration complex subunit RuvB
Electron transfer via tryptophanyl radical
DNA-directed RNA polymerase subunit beta
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
PhoD-like phosphatase metallophosphatase
RNA methyltransferase SpoU/TrmH type C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Sodium symporter small subunit predicted
NAD(P) transhydrogenase alpha subunit C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Flagella basal body P-ring formation protein FlgA
N-acetyl-gamma-glutamyl-phosphate reductase
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Phosphotransferase system enzyme I N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Important for interaction with partner proteins
DNA-directed RNA polymerase subunit alpha
Bifunctional purine biosynthesis protein PurH
Anthranilate synthase component I N-terminal
Putative adhesin domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase A
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Magnesium transporter MgtE intracellular
DNA-directed RNA polymerase subunit omega
Appears to be important in orienting the phosphate for catalysis
Curli production assembly/transport component CsgF
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Peptide methionine sulphoxide reductase MsrA
Succinyl-diaminopimelate desuccinylase 1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cob(I)alamin adenosyltransferase N-terminal
Transition state stabilizer; via amide nitrogen
NIF system FeS cluster assembly NifU N-terminal
FMN-dependent NADH:quinone oxidoreductase
ATP-dependent protease ATPase subunit HslU
High frequency lysogenization protein HflD homolog
Lipopolysaccharide export system protein LptA
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Haemolysin activator HlyB C-terminal domain-containing protein
TonB system biopolymer transport component
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Periplasmic nitrate reductase, electron transfer subunit
Reversibly protonated during proton transport
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Sec-independent protein translocase protein TatA
Ribosomal RNA large subunit methyltransferase F
3,4-dihydroxy-2-butanone 4-phosphate synthase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Involved in Mg(2+) ion dislocation from EF-Tu
Cyclic pyranopterin monophosphate synthase
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Heavy metal binding domain-containing protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Ribosomal RNA large subunit methyltransferase G
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
Bacterial bifunctional deaminase-reductase C-terminal
Probable septum site-determining protein MinC
Glycine zipper domain-containing protein
Lytic transglycosylase superhelical linker