Solute-binding protein family 3/N-terminal
Penicillin-binding protein transpeptidase
Molybdopterin cofactor biosynthesis C (MoaC)
Flagellar basal-body/hook protein C-terminal
Peptide methionine sulphoxide reductase MsrA
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Major facilitator superfamily (MFS) profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
UDP-N-acetylenolpyruvoylglucosamine reductase
Transcription regulator AsnC/Lrp ligand binding
Flagellar basal body rod protein N-terminal
Adenosylcobinamide-GDP ribazoletransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Heat-inducible transcription repressor HrcA C-terminal
DNA-directed RNA polymerase subunit alpha
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
ATP-dependent protease ATPase subunit HslU
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
RNA polymerase sigma factor 70 region 4 type 2
Na+/H+ antiporter MnhB subunit-related protein
Inosine/uridine-preferring nucleoside hydrolase
Gamma-butyrobetaine hydroxylase-like N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gp5/Type VI secretion system Vgr protein OB-fold
RND efflux pump membrane fusion protein barrel-sandwich
Alpha-D-phosphohexomutase alpha/beta/alpha
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycine cleavage T-protein C-terminal barrel
Mandelate racemase/muconate lactonizing enzyme C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Outer membrane protein assembly factor BamD
Probable septum site-determining protein MinC
Probable periplasmic serine endoprotease DegP-like
Plays an important role in substrate specificity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
N-(5'-phosphoribosyl)anthranilate isomerase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Resolvase/invertase-type recombinase catalytic
4'-phosphopantetheinyl transferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Nitrite/Sulfite reductase ferredoxin-like
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Interacts with tRNA; defines subfamily-specific binding signature
Glycosyltransferase subfamily 4-like N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Cytochrome C biogenesis protein transmembrane
Crossover junction endodeoxyribonuclease RuvC
Type IV conjugative transfer protein TrbJ/K C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Pyrimidine nucleoside phosphorylase C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
N-acetyl-gamma-glutamyl-phosphate reductase
ABC transporter substrate-binding protein PnrA-like
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Transcription elongation factor GreA/GreB C-terminal
Membrane fusion protein biotin-lipoyl like
Sugar fermentation stimulation protein homolog
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
SUF system FeS cluster assembly SufBD N-terminal
PHA accumulation regulator DNA-binding N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Phosphatidylglycerol lysyltransferase C-terminal
RNA binding; important for wobble base 34 recognition
Anthranilate synthase component I N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Potassium-transporting ATPase KdpC subunit
Phosphoethanolamine transferase N-terminal
Electron transfer via tryptophanyl radical
Methionyl-tRNA synthetase anticodon-binding
1-aminocyclopropane-1-carboxylate deaminase
General stress protein FMN-binding split barrel
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glycoside hydrolase family 42 N-terminal
DNA-directed DNA polymerase family A palm
Flagellar hook-length control protein-like C-terminal
L,D-transpeptidase catalytic domain-containing protein
Putative Flp pilus-assembly TadG-like N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Polyribonucleotide nucleotidyltransferase
Pyrroline-5-carboxylate reductase catalytic N-terminal
CagE TrbE VirB component of type IV transporter system central
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Release factor glutamine methyltransferase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Probable 5-dehydro-4-deoxyglucarate dehydratase
YbaK/aminoacyl-tRNA synthetase-associated
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Ribosomal RNA small subunit methyltransferase A
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribosomal RNA small subunit methyltransferase G
Cysteine sulfenic acid (-SOH) intermediate
Ribose-phosphate pyrophosphokinase N-terminal
3-methyl-2-oxobutanoate hydroxymethyltransferase
Glucose-methanol-choline oxidoreductase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glutamate synthase alpha subunit C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Tannase/feruloyl esterase family alpha/beta hydrolase
Glycosyltransferase family 28 N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Probable transcriptional regulatory protein Avi_3631
Bacterial type II secretion system protein E
Leucine-binding protein domain-containing protein
Outer membrane protein assembly factor BamA
PhoD-like phosphatase metallophosphatase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ionotropic glutamate receptor C-terminal
Probable flagellum biosynthesis repressor protein FlbT
Glutamyl-tRNA(Gln) amidotransferase subunit A
ABC-type glycine betaine transport system substrate-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Phenylalanine--tRNA ligase alpha subunit
Putative auto-transporter adhesin head GIN
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Endoribonuclease L-PSP/chorismate mutase-like
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Holliday junction branch migration complex subunit RuvB
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Flagellar motor switch protein FliN-like C-terminal
4-hydroxy-tetrahydrodipicolinate reductase
Deoxyguanosinetriphosphate triphosphohydrolase-like protein
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Saccharopine dehydrogenase-like C-terminal
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Could play a key role in the communication between the regulatory and the substrate sites
Glycosyl transferase family 28 C-terminal
ABC transporter substrate-binding protein PnrA-like domain-containing protein
Glycosyl-hydrolase family 116 catalytic region
Cob(I)alamin adenosyltransferase N-terminal
Invasion associated locus B family protein
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Polysaccharide biosynthesis protein C-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Tryptophan synthase beta chain-like PALP
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Oxygen-dependent coproporphyrinogen-III oxidase
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
NAD(P) transhydrogenase alpha subunit C-terminal
3-isopropylmalate dehydratase small subunit
Tripartite tricarboxylate transporter substrate binding protein
Beta-lactamase hydrolase-like protein phosphatase-like
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
Interaction with polymerase core subunit RpoC
Putative pyruvate, phosphate dikinase regulatory protein
Cytochrome c oxidase subunit IV bacterial aa3 type
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
TonB-dependent receptor-like beta-barrel
ATP-dependent DNA helicase RecG C-terminal
Terminase large subunit gp17-like C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Probable inorganic carbon transporter subunit DabA
Cytochrome c-type biogenesis protein CcmF C-terminal
Polysaccharide chain length determinant N-terminal
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Phosphoribosylformylglycinamidine cyclo-ligase
6-phosphogluconate dehydrogenase C-terminal
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
NADPH-dependent 7-cyano-7-deazaguanine reductase
Putative pterin-4-alpha-carbinolamine dehydratase
Sec-independent protein translocase protein TatA
Signal transduction histidine kinase HWE region
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription factor NikR nickel binding C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
(S)-ureidoglycine aminohydrolase cupin domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aminoacyl-transfer RNA synthetases class-II family profile
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Terminase large subunit-like endonuclease
Leucyl/phenylalanyl-tRNA--protein transferase
DNA-directed RNA polymerase subunit omega
O-(3'-phospho-DNA)-tyrosine intermediate
ATP phosphoribosyltransferase regulatory subunit
Prepilin type IV endopeptidase peptidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Ribosomal RNA large subunit methyltransferase E
Involved in Mg(2+) ion dislocation from EF-Tu
Succinate--CoA ligase [ADP-forming] subunit beta
5-glutamyl coenzyme A thioester intermediate
ATP-dependent Clp protease ATP-binding subunit ClpX
Carbamoyl-phosphate synthase small subunit N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Cell division topological specificity factor
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Peptidase S9 prolyl oligopeptidase catalytic
Ribosomal RNA small subunit methyltransferase H
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Could be important to modulate the pK values of the two catalytic cysteine residues
Chromosomal replication initiator protein DnaA
UDP-glucose/GDP-mannose dehydrogenase C-terminal
3-isopropylmalate dehydratase large subunit
Important for interaction with partner proteins
HicB-like antitoxin of toxin-antitoxin system
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Thiamin pyrophosphokinase thiamin-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Tip attachment protein J domain-containing protein
Oxidoreductase molybdopterin-binding domain-containing protein
Involved in allosteric activation by GTP
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcription antitermination protein NusB
Cytochrome b561 bacterial/Ni-hydrogenase
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Alanyl-transfer RNA synthetases family profile
Required for zinc-mediated homotetramerization and catalytic activity
Potassium-transporting ATPase potassium-binding subunit
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Extensin-like C-terminal domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Sodium/calcium exchanger membrane region
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-245)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-97)
Histidine phosphotransferase ChpT C-terminal
Prokaryotic-type class I peptide chain release factors
Reversibly protonated during proton transport
Phosphoribosylformylglycinamidine synthase subunit PurL
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Transposase IS116/IS110/IS902 C-terminal
Flagella basal body P-ring formation protein FlgA
Flagella basal body P-ring formation protein FlgA C-terminal
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Ribosomal RNA large subunit methyltransferase H
Chromosomal replication initiator DnaA C-terminal
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
Heme-copper oxidase subunit III family profile
NIF system FeS cluster assembly NifU N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Proton acceptor; for glutaminase activity
NADH-rubredoxin oxidoreductase C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
SsuA/THI5-like domain-containing protein
Organic solvent tolerance-like N-terminal
Cobaltochelatase subunit CobS N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Bacteriophage tail tape measure N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
C4-dicarboxylate ABC transporter substrate-binding protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Holliday junction branch migration complex subunit RuvA
N-sulphoglucosamine sulphohydrolase C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
Adaptive response protein AidB N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
DNA replication/recombination mediator RecO N-terminal
CDP-alcohol phosphatidyltransferase C-terminal
Dual-specificity RNA methyltransferase RlmN
DNA-directed RNA polymerase subunit beta
Sigma 54 modulation/S30EA ribosomal protein C-terminal
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase