Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Gly-cisPro motif, important for rejection of L-amino acids
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Transferrin-binding protein B N-lobe handle
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Probable transposase IS891/IS1136/IS1341
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Polypeptide-transport-associated ShlB-type
RNA binding; important for wobble base 34 recognition
Disulphide bond isomerase DsbC/G N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Small ribosomal subunit protein uS4 N-terminal
Prokaryotic-type class I peptide chain release factors
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Na(+)-translocating NADH-quinone reductase subunit C
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glucose-methanol-choline oxidoreductase N-terminal
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like stalk
Required for zinc-mediated homotetramerization and catalytic activity
Tryptophan synthase beta chain-like PALP
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Cytochrome b561 bacterial/Ni-hydrogenase
Membrane insertase YidC/Oxa/ALB C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Outer membrane protein beta-barrel domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
TonB-dependent receptor-like beta-barrel
Resolvase/invertase-type recombinase catalytic
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Erythronate-4-phosphate dehydrogenase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Major facilitator superfamily (MFS) profile
LexA-binding, inner membrane-associated hydrolase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyruvate dehydrogenase E1 component middle
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Type IV secretion system coupling protein TraD DNA-binding
3-hydroxyacyl-CoA dehydrogenase NAD binding
Prepilin type IV endopeptidase peptidase
Beta-lactamase hydrolase-like protein phosphatase-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Interaction with polymerase core subunit RpoC
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Trimeric autotransporter adhesin YadA-like head
Polymerase/histidinol phosphatase N-terminal
Exonuclease VII large subunit C-terminal
Transferrin binding protein-like solute binding protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycine cleavage T-protein C-terminal barrel
Bacterial type II secretion system protein E
Interacts with tRNA; defines subfamily-specific binding signature
Glycosyl transferase family 3 N-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
Nitrite/Sulfite reductase ferredoxin-like
Chromosomal replication initiator DnaA C-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Helix-hairpin-helix DNA-binding motif class 1
RND efflux pump membrane fusion protein barrel-sandwich
N6 adenine-specific DNA methyltransferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Urease accessory protein UreH-like transmembrane
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Seems to be a necessary countercharge to the potassium cations
Essential for prephenate dehydratase activity
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
NIF system FeS cluster assembly NifU N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Quercetin 2,3-dioxygenase C-terminal cupin
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
3-hydroxyacyl-CoA dehydrogenase C-terminal
Positions MEP for the nucleophilic attack
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phage-Barnase-EndoU-ColicinE5/D-RelE-like nuclease
Glutathionylspermidine synthase pre-ATP-grasp-like
Molybdopterin cofactor biosynthesis C (MoaC)
Outer membrane protein assembly factor BamA
NADH:ubiquinone oxidoreductase 30kDa subunit
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Could be important to modulate the pK values of the two catalytic cysteine residues
Proline utilization A proline dehydrogenase N-terminal
Type I restriction modification DNA specificity
Plays an important role in substrate specificity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Acyl-CoA dehydrogenase N-terminal bacteria
Threonine/serine exporter-like N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Sodium symporter small subunit predicted
Saccharopine dehydrogenase-like C-terminal
Chromosomal replication initiator protein DnaA
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Penicillin-binding protein transpeptidase
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA-directed DNA polymerase family A palm
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Alanyl-transfer RNA synthetases family profile
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Reversibly protonated during proton transport
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Terminase large subunit-like endonuclease
Peptide methionine sulphoxide reductase MsrA
General stress protein FMN-binding split barrel
Large ribosomal subunit protein uL2 C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Anthranilate synthase component I N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein uL15/eL18
Important for interaction with partner proteins
UDP-glucose/GDP-mannose dehydrogenase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
NIF system FeS cluster assembly NifU C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Important for substrate binding and specificity
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Aminoacyl-tRNA synthetase class I anticodon-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aconitase A/isopropylmalate dehydratase small subunit swivel
Co-chaperone HscB C-terminal oligomerisation
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Translation elongation factor P/YeiP central
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
YbaK/aminoacyl-tRNA synthetase-associated
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Pseudouridine synthase I TruA alpha/beta
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Sodium/calcium exchanger membrane region
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal