Flagellar motor switch protein FliN-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 3/N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Bacterial type II secretion system protein E
Ionotropic glutamate receptor C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Transcription elongation factor GreA/GreB C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Malonate/sodium symporter MadM subunit N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Large ribosomal subunit protein uL6 alpha-beta
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
ABC-type glycine betaine transport system substrate-binding
Major facilitator superfamily (MFS) profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Phosphoadenosine phosphosulphate reductase
YbaK/aminoacyl-tRNA synthetase-associated
TonB-dependent receptor-like beta-barrel
RNA polymerase sigma factor 70 region 4 type 2
ABC-type uncharacterised transport system
Mandelate racemase/muconate lactonizing enzyme C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Putative beta-barrel assembly-enhancing protease
Cation-transporting P-type ATPase N-terminal
Anthranilate synthase component I N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Tryptophan synthase beta chain-like PALP
Pseudouridine synthase I TruA alpha/beta
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Penicillin-binding protein transpeptidase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
O-(5'-phospho-DNA)-tyrosine intermediate
Cob(I)alamin adenosyltransferase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Important for interaction with partner proteins
Plays an important role in substrate specificity
Prokaryotic-type class I peptide chain release factors
O-(3'-phospho-DNA)-tyrosine intermediate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cytochrome b561 bacterial/Ni-hydrogenase
Glucan biosynthesis periplasmic MdoG C-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alpha-glycerophosphate oxidase C-terminal
Guanylate kinase/L-type calcium channel beta subunit
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Water stress and hypersensitive response
Membrane fusion protein biotin-lipoyl like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Positions MEP for the nucleophilic attack
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Type 4 fimbrial biogenesis protein PilX N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
N-end rule aminoacyl transferase C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Interaction with polymerase core subunit RpoC
Gp5/Type VI secretion system Vgr protein OB-fold
Heme-copper oxidase subunit III family profile
Glycosyl transferase family 3 N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Translation elongation factor P/YeiP central
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH:ubiquinone oxidoreductase-like 20kDa subunit
S-adenosylmethionine-dependent methyltransferase
NAD(P) transhydrogenase alpha subunit C-terminal
Schiff-base intermediate with acetaldehyde
Mannose-6-phosphate isomerase type II C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Putative regulatory protein FmdB Zinc ribbon
Phosphatidylglycerol lysyltransferase C-terminal
Outer membrane protein assembly factor BamD
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Helix-hairpin-helix DNA-binding motif class 1
Polysaccharide chain length determinant N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Outer membrane protein assembly factor BamA
Membrane insertase YidC/Oxa/ALB C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gamma-butyrobetaine hydroxylase-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Murein L,D-transpeptidase catalytic domain family protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribosomal RNA adenine methylase transferase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
ATP synthase F1 complex delta/epsilon subunit N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA polymerase III delta subunit C-terminal
Spermidine/putrescine ABC transporter substrate-binding protein
Quercetin 2,3-dioxygenase C-terminal cupin
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Outer membrane protein assembly factor BamB
O-(phosphoribosyl dephospho-coenzyme A)serine
ABC-type transport auxiliary lipoprotein component
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For 3-hydroxyacyl-CoA dehydrogenase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycoside hydrolase family 42 N-terminal
Polymerase/histidinol phosphatase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Nitrite/Sulfite reductase ferredoxin-like
Gamma-glutamylcyclotransferase AIG2-like
Alanyl-transfer RNA synthetases family profile
DNA-directed DNA polymerase family A palm
Disulphide bond isomerase DsbC/G N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Plays an important role in discriminating NADH against NADPH
Chromosomal replication initiator DnaA C-terminal
Seems to be a necessary countercharge to the potassium cations
Lipocalin-like domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Reversibly protonated during proton transport
Important for substrate binding and specificity
Shikimate dehydrogenase substrate binding N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Carbamoyl-phosphate synthase small subunit N-terminal
Membrane-bound lytic murein transglycosylase A
Curli production assembly/transport component CsgG
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Saccharopine dehydrogenase-like C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Probable periplasmic serine endoprotease DegP-like
Chromosomal replication initiator protein DnaA
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Arginine decarboxylase C-terminal helical
Large ribosomal subunit protein uL2 C-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Fimbrial-type adhesion domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Prepilin type IV endopeptidase peptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA mismatch repair proteins mutS family
HicB-like antitoxin of toxin-antitoxin system
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Translocation and assembly module subunit TamA
Glucosamine/galactosamine-6-phosphate isomerase
Flagellar hook-length control protein-like C-terminal
DNA replication/recombination mediator RecO N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Sugar fermentation stimulation protein C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Endolytic peptidoglycan transglycosylase RlpA
Large ribosomal subunit protein uL15/eL18
Regulator of nucleoside diphosphate kinase N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Hypersensitivity response secretion-like HrpJ
NIF system FeS cluster assembly NifU N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
RNA 2-O ribose methyltransferase substrate binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Could be important to modulate the pK values of the two catalytic cysteine residues
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Mechanosensitive ion channel inner membrane
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Na+/H+ antiporter MnhB subunit-related protein
Ribose-phosphate pyrophosphokinase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NIF system FeS cluster assembly NifU C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Peptide methionine sulphoxide reductase MsrA