Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Tryptophan synthase beta chain-like PALP
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Flagellar motor switch protein FliN-like C-terminal
Major facilitator superfamily associated
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Curli production assembly/transport component CsgG
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribosomal RNA adenine methylase transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ysc84 actin-binding domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
Mechanosensitive ion channel protein MscS
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
ATP synthase F1 complex delta/epsilon subunit N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Major facilitator superfamily (MFS) profile
Ribulose bisphosphate carboxylase small subunit
Proton acceptor; for glutaminase activity
Membrane fusion protein biotin-lipoyl like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
HupH hydrogenase expression protein C-terminal
Solitary outer membrane autotransporter beta-barrel
Solitary outer membrane autotransporter beta-barrel domain-containing protein
CD-NTase-associated protein 12/Pycsar effector protein TIR
Fe/B12 periplasmic-binding domain-containing protein
6-hydroxymethylpterin diphosphokinase MptE-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Gamma-glutamylcyclotransferase AIG2-like
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Glycoside hydrolase family 57 N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Prepilin type IV endopeptidase peptidase
Glucosamine/galactosamine-6-phosphate isomerase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Alpha-D-phosphohexomutase alpha/beta/alpha
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Outer-membrane lipoprotein carrier protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Flagellar assembly protein T middle domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Inner membrane protein YgaP-like transmembrane
Sodium/calcium exchanger membrane region
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Flagellar hook-length control protein-like C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Chromosomal replication initiator DnaA C-terminal
Urease accessory protein UreH-like transmembrane
Gamma-butyrobetaine hydroxylase-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
SsuA/THI5-like domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polysaccharide biosynthesis protein CapD-like
Heat-inducible transcription repressor HrcA C-terminal
Polymerase/histidinol phosphatase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Disulphide bond isomerase DsbC/G N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alanyl-transfer RNA synthetases family profile
Glycosyl transferase family 3 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Interaction with polymerase core subunit RpoC
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL6 alpha-beta
Prokaryotic-type class I peptide chain release factors
Release factor glutamine methyltransferase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Could be important to modulate the pK values of the two catalytic cysteine residues
Plays an important role in substrate specificity
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aconitase A/isopropylmalate dehydratase small subunit swivel
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Penicillin-binding protein transpeptidase
Important for substrate binding and specificity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type I restriction modification DNA specificity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA mismatch repair proteins mutS family
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Could play a key role in the communication between the regulatory and the substrate sites
Membrane insertase YidC/Oxa/ALB C-terminal
Organic solvent tolerance-like N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Outer membrane protein assembly factor BamC
DNA-directed DNA polymerase family A palm
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Ribulose bisphosphate carboxylase large chain 2
Carbamoyl-phosphate synthase small subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Molybdopterin cofactor biosynthesis C (MoaC)
Pyruvate phosphate dikinase AMP/ATP-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL15/eL18
Reversibly protonated during proton transport
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Anthranilate synthase component I N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
C-type lysozyme inhibitor domain-containing protein
Molybdate ABC transporter substrate-binding protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Cation-transporting P-type ATPase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Transcription factor NikR nickel binding C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Twin-arginine translocation signal domain-containing protein
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
RNA 2-O ribose methyltransferase substrate binding
TonB-dependent receptor-like beta-barrel
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
6-phosphogluconate dehydrogenase C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Choloylglycine hydrolase/NAAA C-terminal
Choloylglycine hydrolase/NAAA C-terminal domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Translation elongation factor P/YeiP central
Lysidine-tRNA(Ile) synthetase C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Exonuclease VII large subunit C-terminal
Thiol:disulfide interchange protein DsbD
Glycosyltransferase subfamily 4-like N-terminal
Thioredoxin-like fold domain-containing protein
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Serine aminopeptidase S33 domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Mannose-6-phosphate isomerase type II C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Metallo-beta-lactamase domain-containing protein
Transglycosylase SLT domain-containing protein
Lipoprotein SmpA/OmlA domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
DNA replication/recombination mediator RecO N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
RNA binding; important for wobble base 34 recognition
Flagellar assembly protein FliH/Type III secretion system HrpE
Helix-hairpin-helix DNA-binding motif class 1
Electron transfer via tryptophanyl radical
Zinc ABC transporter substrate-binding protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glycine cleavage T-protein C-terminal barrel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B