RND efflux pump membrane fusion protein barrel-sandwich
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Phosphoadenosine phosphosulphate reductase
TonB-dependent receptor-like beta-barrel
Peptidase S9 prolyl oligopeptidase catalytic
Peptidoglycan recognition protein family
BAAT/Acyl-CoA thioester hydrolase C-terminal
Asl1-like glycosyl hydrolase catalytic domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Polysaccharide chain length determinant N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
RNA polymerase sigma factor 70 region 4 type 2
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Polysaccharide biosynthesis protein C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
N-sulphoglucosamine sulphohydrolase C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Surface glycan-binding protein B xyloglucan binding
Surface glycan-binding protein B xyloglucan binding domain-containing protein
RNA binding; important for wobble base 34 recognition
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Thiamine pyrophosphate enzyme TPP-binding
Chromosomal replication initiator DnaA C-terminal
Major facilitator superfamily (MFS) profile
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Signal transduction histidine kinase internal region
Cysteine sulfenic acid (-SOH) intermediate
Glycosyltransferase subfamily 4-like N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Threonine/serine exporter-like N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Intracellular exo-alpha-L-arabinofuranosidase
Meso-diaminopimelate D-dehydrogenase C-terminal
Release factor glutamine methyltransferase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
General stress protein FMN-binding split barrel
Fibrobacter succinogenes major paralogous
Beta-hexosaminidase bacterial type N-terminal
Tryptophan synthase beta chain-like PALP
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glycosyl hydrolase family 30 beta sandwich
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
Small ribosomal subunit protein uS4 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
N6 adenine-specific DNA methyltransferase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
6-phosphogluconate dehydrogenase C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Putative beta-lactamase-inhibitor-like PepSY-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycoside hydrolase Family 18, chitinase_18
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Helix-hairpin-helix DNA-binding motif class 1
Reversibly protonated during proton transport
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycoside hydrolase family 31 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Thymidylate synthase/dCMP hydroxymethylase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
UDP-glucose/GDP-mannose dehydrogenase dimerisation
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Schiff-base intermediate with substrate; via pyruvic acid
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Aspartate/homoserine dehydrogenase NAD-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyl-hydrolase 97 C-terminal oligomerisation
SusD-like N-terminal domain-containing protein
Outer membrane lipoprotein carrier protein LolA
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Major fimbrial subunit protein N-terminal
Major fimbrial subunit protein N-terminal domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
DNA mismatch repair proteins mutS family
Lysidine-tRNA(Ile) synthetase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Phosphoethanolamine transferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Polymerase/histidinol phosphatase N-terminal
Fimbrial subunit protein C-terminal domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Menaquinone biosynthesis protein MenD middle
Membrane fusion protein biotin-lipoyl like
Chitobiase/beta-hexosaminidases N-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alanyl-transfer RNA synthetases family profile
Polysaccharide lyase family 8 C-terminal
Putative acyltransferase ACT14924-like acyltransferase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Bacterial alpha-L-rhamnosidase N-terminal
Plays an important role in maintaining the position of the catalytic nucleophile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Cytochrome oxidase subunit II transmembrane region profile
Phosphatidylglycerol lysyltransferase C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Saccharopine dehydrogenase-like C-terminal
Bacterial transcription activator effector binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Transposase IS116/IS110/IS902 C-terminal
DNA-directed DNA polymerase family A palm
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Alginate lyase domain-containing protein
Alpha-galactosidase NEW3 domain-containing protein
Organic solvent tolerance-like N-terminal
Translation elongation factor P/YeiP central
ABC-type glycine betaine transport system substrate-binding
Plays an important role in substrate specificity
Prokaryotic-type class I peptide chain release factors
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Choloylglycine hydrolase/NAAA C-terminal
Penicillin-binding protein transpeptidase
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
RNA 2-O ribose methyltransferase substrate binding
Beta-lactamase superfamily domain-containing protein
Gylcosyl hydrolase 115 C-terminal domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Proton acceptor; for glutaminase activity
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Myo-inositol-1-phosphate synthase GAPDH-like
Type I restriction enzyme R protein N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
ATPsynthase alpha/beta subunit N-terminal extension
Cell division protein FtsQ/DivIB C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATP-dependent DNA helicase RecG C-terminal
Phage terminase large subunit N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
SusE outer membrane protein domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Solute-binding protein family 3/N-terminal
Substrate import-associated zinc metallohydrolase lipoprotein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RagB/SusD family nutrient uptake outer membrane protein
Trigger factor ribosome-binding bacterial
tRNA pseudouridylate synthase B C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycine cleavage T-protein C-terminal barrel
F420-non-reducing hydrogenase iron-sulfur subunit D
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Shikimate dehydrogenase substrate binding N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL2 C-terminal
Arabinogalactan endo-beta-1,4-galactanase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alginate export domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Resolvase/invertase-type recombinase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycoside hydrolase family 42 N-terminal
Outer membrane protein transport protein (OMPP1/FadL/TodX)
Anti-bacteriophage protein A/HamA C-terminal
Bacteroidetes PKD-like domain-containing protein
Glycoside hydrolase GH146 substrate-binding
Type I restriction modification DNA specificity
Gly-cisPro motif, important for rejection of L-amino acids
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Putative auto-transporter adhesin head GIN
Arginine decarboxylase C-terminal helical
Ribose-phosphate pyrophosphokinase N-terminal
Essential for prephenate dehydratase activity
DNA replication/recombination mediator RecO N-terminal
Conserved virulence factor B-like winged helix
LamG-like jellyroll fold domain-containing protein
Alpha galactosidase C-terminal beta sandwich
Ribosome maturation factor RimP N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Positions MEP for the nucleophilic attack
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cation-transporting P-type ATPase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL15/eL18