Myo-inositol-1-phosphate synthase GAPDH-like
Cell envelope-related transcriptional attenuator
Peptidase M1 membrane alanine aminopeptidase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Polymerase/histidinol phosphatase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Major facilitator superfamily (MFS) profile
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aminoacyl-transfer RNA synthetases class-II family profile
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Alpha-glycerophosphate oxidase C-terminal
AraC-type arabinose-binding/dimerisation
Putative Flp pilus-assembly TadG-like N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Restriction system protein Mrr-like N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Siderophore-interacting protein C-terminal
Tryptophan synthase beta chain-like PALP
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RNA binding; important for wobble base 34 recognition
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pyruvate dehydrogenase E1 component middle
Penicillin-binding protein transpeptidase
NIF system FeS cluster assembly NifU N-terminal
Peptide methionine sulphoxide reductase MsrA
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Translation elongation factor P/YeiP central
Bacterial bifunctional deaminase-reductase C-terminal
Positions MEP for the nucleophilic attack
Plays an important role in substrate specificity
Chromosomal replication initiator DnaA C-terminal
Anthranilate synthase component I N-terminal
Phosphatidate phosphatase APP1 catalytic
RNA 2-O ribose methyltransferase substrate binding
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL6 alpha-beta
ATP-dependent DNA helicase RecG C-terminal
Ribosome maturation factor RimP N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
DNA-directed DNA polymerase family A palm
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Interaction with polymerase core subunit RpoC
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Exonuclease VII large subunit C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Phosphoadenosine phosphosulphate reductase
Phosphatidylglycerol lysyltransferase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ABC-type glycine betaine transport system substrate-binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Glycine cleavage T-protein C-terminal barrel
Prokaryotic-type class I peptide chain release factors
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Na+/H+ antiporter MnhB subunit-related protein
Ribosomal RNA adenine methylase transferase N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Alanyl-transfer RNA synthetases family profile
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Threonine/serine exporter-like N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Bacterial type II secretion system protein E
Cytochrome b/b6 N-terminal region profile
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptidase S9 prolyl oligopeptidase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Carbamoyl-phosphate synthetase large subunit-like ATP-binding
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Endoribonuclease L-PSP/chorismate mutase-like
N6 adenine-specific DNA methyltransferase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Large ribosomal subunit protein uL2 C-terminal
Phosphotransferase system enzyme I N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Aconitase A/isopropylmalate dehydratase small subunit swivel
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
6-phosphogluconate dehydrogenase C-terminal
Important for beta-aspartyl-AMP intermediate formation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cytochrome C biogenesis protein transmembrane
Shikimate dehydrogenase substrate binding N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Type I restriction modification DNA specificity
Pseudouridine synthase I TruA alpha/beta
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Alpha-D-phosphohexomutase alpha/beta/alpha
Sigma 54 modulation/S30EA ribosomal protein C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Beta-lactamase-related domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Formamidopyrimidine-DNA glycosylase catalytic
YbaK/aminoacyl-tRNA synthetase-associated
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glucose-methanol-choline oxidoreductase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phosphocysteine intermediate; for EIIB activity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Release factor glutamine methyltransferase N-terminal
SGNH hydrolase-type esterase domain-containing protein
Schiff-base intermediate with D-ribose 5-phosphate
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Iron ABC transporter substrate-binding protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Phosphomannose isomerase type I C-terminal
Phosphomannose isomerase type I catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
CobB/CobQ-like glutamine amidotransferase
4'-phosphopantetheinyl transferase N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Phosphoribosylformylglycinamidine synthase linker
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL15/eL18
Essential for prephenate dehydratase activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Phenol hydroxylase C-terminal dimerisation
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Electron transfer via tryptophanyl radical
Involved in ionization of N3 of dUMP, leading to its activation
Reversibly protonated during proton transport
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycosyl transferase family 3 N-terminal
DNA replication/recombination mediator RecO N-terminal
Small ribosomal subunit protein uS4 N-terminal