Peptide methionine sulphoxide reductase MsrA
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
NADH:ubiquinone oxidoreductase 30kDa subunit
Endolytic peptidoglycan transglycosylase RlpA
Putative regulatory protein FmdB Zinc ribbon
Major facilitator superfamily (MFS) profile
Mannose-6-phosphate isomerase type II C-terminal
Ribulose bisphosphate carboxylase small subunit
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosomal RNA adenine methylase transferase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Large ribosomal subunit protein uL2 C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
RNA binding; important for wobble base 34 recognition
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophan synthase beta chain-like PALP
Type III secretion system flagellar brake protein YcgR PilZN
Phosphotransferase system enzyme I N-terminal
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Polysaccharide biosynthesis protein C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Cysteine sulfenic acid (-SOH) intermediate
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
RNA polymerase sigma factor 70 region 4 type 2
Membrane insertase YidC/Oxa/ALB C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
S-adenosyl-L-homocysteine hydrolase NAD binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Helix-hairpin-helix DNA-binding motif class 1
Aromatic hydrocarbon degradation protein
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Positions MEP for the nucleophilic attack
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
O-(3'-phospho-DNA)-tyrosine intermediate
Polymerase/histidinol phosphatase N-terminal
Release factor glutamine methyltransferase N-terminal
Outer membrane protein assembly factor BamA
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Type IV secretion system coupling protein TraD DNA-binding
Blue (type 1) copper domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Exonuclease VII large subunit C-terminal
Bacterial type II secretion system protein E
Interaction with polymerase core subunit RpoC
TonB-dependent receptor-like beta-barrel
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Important for substrate binding and specificity
Type II secretion system protein GspE N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
NIF system FeS cluster assembly NifU N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Reversibly protonated during proton transport
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
N6 adenine-specific DNA methyltransferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Required for zinc-mediated homotetramerization and catalytic activity
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Nitrite/Sulfite reductase ferredoxin-like
Could be important to modulate the pK values of the two catalytic cysteine residues
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
S-adenosylmethionine-dependent methyltransferase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Restriction endonuclease type II EcoRII C-terminal
HupH hydrogenase expression protein C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Leucine-binding protein domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Antitoxin Xre/MbcA/ParS-like toxin-binding
6-phosphogluconate dehydrogenase C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Sodium/calcium exchanger membrane region
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Heme-copper oxidase subunit III family profile
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cytochrome oxidase subunit II copper A binding
Glucosamine/galactosamine-6-phosphate isomerase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycoside hydrolase family 57 N-terminal
Schiff-base intermediate with substrate; via topaquinone
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Divergent polysaccharide deacetylase family protein
Restriction system protein Mrr-like N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Glycine zipper 2TM domain-containing protein
ABC transporter substrate-binding protein PnrA-like
Translation elongation factor P/YeiP central
Tetratricopeptide repeat-like domain-containing protein
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Thioredoxin-like fold domain-containing protein
Inner membrane protein YgaP-like transmembrane
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Solute-binding protein family 3/N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Urease accessory protein UreH-like transmembrane
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Solute-binding protein family 5 domain-containing protein
NADH-rubredoxin oxidoreductase C-terminal
Arginine decarboxylase C-terminal helical
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Membrane fusion protein biotin-lipoyl like
Serine/threonine specific protein phosphatases
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Prokaryotic-type class I peptide chain release factors
Outer membrane protein beta-barrel domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Integral membrane protein YccS N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phosphoadenosine phosphosulphate reductase
Transglycosylase SLT domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Nucleophile; cysteine thiosulfonate intermediate
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
ABC-type uncharacterised transport system
EfeO-type cupredoxin-like domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA-directed DNA polymerase family A palm
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
NADH:ubiquinone oxidoreductase chain 4 N-terminal
SsuA/THI5-like domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Required for dimer formation and molybdate binding
Type I restriction modification DNA specificity
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Outer-membrane lipoprotein carrier protein
Secretin/TonB short N-terminal domain-containing protein
Dinitrogenase iron-molybdenum cofactor N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
N-end rule aminoacyl transferase C-terminal
Schiff-base intermediate with dihydroxyacetone-P
DnaJ homologue subfamily C member 28 conserved
Nitrogenase molybdenum-iron protein beta chain N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
High potential iron-sulfur proteins family profile
Proton acceptor; for glutaminase activity
Cytochrome oxidase subunit II transmembrane region profile
Large ribosomal subunit protein uL15/eL18
NAD(P) transhydrogenase alpha subunit C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
YbaK/aminoacyl-tRNA synthetase-associated
Important for beta-aspartyl-AMP intermediate formation
Prepilin type IV endopeptidase peptidase
Glucan biosynthesis periplasmic MdoG C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal domain-containing protein
ABC-type transport auxiliary lipoprotein component
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Essential for prephenate dehydratase activity
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Outer membrane protein assembly factor BamD
Solute-binding protein family 3/N-terminal domain-containing protein
DNA polymerase III delta subunit C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NIF system FeS cluster assembly NifU C-terminal
Plays an important role in substrate specificity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Probable transposase IS891/IS1136/IS1341
Gly-cisPro motif, important for rejection of L-amino acids
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Electron transfer via tryptophanyl radical
ParB-related ThiF-related cassette protein E
Peptidoglycan binding-like domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Gamma-butyrobetaine hydroxylase-like N-terminal
DNA mismatch repair proteins mutS family
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pseudouridine synthase I TruA alpha/beta
Interacts with tRNA; defines subfamily-specific binding signature
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
UDP N-acetylglucosamine O-acyltransferase C-terminal
Anthranilate synthase component I N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glycine-zipper-containing OmpA-like membrane domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Carbamoyl-phosphate synthase small subunit N-terminal