DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Activator of Hsp90 ATPase homologue 1-like C-terminal
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Prokaryotic-type class I peptide chain release factors
Glucose-methanol-choline oxidoreductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cytochrome c-type biogenesis protein CcmF C-terminal
S-adenosylmethionine-dependent methyltransferase
Major facilitator superfamily (MFS) profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Alginate export domain-containing protein
Signal recognition particle SRP54 helical bundle
Conjugal transfer pilus assembly protein TraV
Holliday junction branch migration complex subunit RuvB
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Glycosyltransferase subfamily 4-like N-terminal
Tryptophan synthase beta chain-like PALP
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Peptidase S9 prolyl oligopeptidase catalytic
BAAT/Acyl-CoA thioester hydrolase C-terminal
Organic solvent tolerance-like N-terminal
Chromosomal replication initiator protein DnaA
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Ribosomal RNA small subunit methyltransferase G
DNA-directed RNA polymerase subunit beta
DNA-directed DNA polymerase family A palm
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Surface antigen domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
TonB-dependent receptor-like beta-barrel
Pyruvate phosphate dikinase AMP/ATP-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cytochrome c biogenesis ATP-binding export protein CcmA
Beta-lactamase hydrolase-like protein phosphatase-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA 2-O ribose methyltransferase substrate binding
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Probable potassium transport system protein Kup 1
4-hydroxy-tetrahydrodipicolinate synthase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Glycoside-hydrolase family GH114 TIM-barrel
Proline utilization A proline dehydrogenase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Quinohemoprotein amine dehydrogenase gamma subunit structural
Probable glycine dehydrogenase (decarboxylating) subunit 1
Heat-inducible transcription repressor HrcA
Sec-independent protein translocase protein TatB
Probable inorganic carbon transporter subunit DabA
RNA polymerase sigma factor 70 region 4 type 2
Penicillin-binding protein transpeptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Alpha-glycerophosphate oxidase C-terminal
Adenosylcobinamide-GDP ribazoletransferase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Lipoprotein-releasing system ATP-binding protein LolD
Protein O-mannosyl-transferase C-terminal four TM
Electron transfer via tryptophanyl radical
PEP-CTERM protein-sorting domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA mismatch repair proteins mutS family
Heme-copper oxidase subunit III family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Putative pyruvate, phosphate dikinase regulatory protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Small-conductance mechanosensitive channel
UDP-N-acetylenolpyruvoylglucosamine reductase
Cyclic pyranopterin monophosphate synthase
RNA binding; important for wobble base 34 recognition
8'-apo-carotenoid 13,14-cleaving dioxygenase
Almost loss of activity. Strong decrease in iron content.
Loss of activity. Strong decrease in iron content.
DNA-directed RNA polymerase subunit omega
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Crossover junction endodeoxyribonuclease RuvC
Pili assembly chaperone N-terminal domain-containing protein
Conjugal transfer pilus assembly protein TraK
Peptide methionine sulphoxide reductase MsrA
Membrane fusion protein biotin-lipoyl like
Essential for prephenate dehydratase activity
Outer membrane protein assembly factor BamD
Type IV secretion system coupling protein TraD DNA-binding
Glucosamine/galactosamine-6-phosphate isomerase
FAD-dependent oxidoreductase 2 FAD binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Shikimate dehydrogenase substrate binding N-terminal
Ribosomal RNA large subunit methyltransferase H
Interaction with polymerase core subunit RpoC
Reversibly protonated during proton transport
Ribosomal protein uS12 methylthiotransferase RimO
Phosphatidylglycerol lysyltransferase C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
3-methyl-2-oxobutanoate hydroxymethyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine cyclo-ligase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA large subunit methyltransferase E
Terminase large subunit gp17-like C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
O-(5'-phospho-DNA)-tyrosine intermediate
Prepilin type IV endopeptidase peptidase
Methylamine/Aralkylamine dehydrogenase light chain C-terminal
Tryptophylquinone 6'-substrate hemiaminal intermediate
Cysteine sulfenic acid (-SOH) intermediate
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Polysaccharide chain length determinant N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Succinate--CoA ligase [ADP-forming] subunit beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
N-succinylglutamate 5-semialdehyde dehydrogenase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Important for activity and substrate specificity; Ala is observed in family members with high D-mannonate dehydratase activity that have no activity with D-gluconate
Inner membrane protein YgaP-like transmembrane
ATP-dependent Clp protease proteolytic subunit
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphoribosylformylglycinamidine synthase subunit PurQ
Phosphoribosylformylglycinamidine synthase subunit PurL
Abolishes glutathione-dependent ATP hydrolysis.
Increases basal rate of ATP hydrolysis and abolishes stimulation of ATP hydrolysis by glutathione.
Strongly increases basal rate of ATP hydrolysis.
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phenylalanine--tRNA ligase alpha subunit
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
Outer membrane protein beta-barrel domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
Bacterial type II secretion system protein E
Peptide methionine sulfoxide reductase MsrA
Ribosomal RNA small subunit methyltransferase A
Holliday junction branch migration complex subunit RuvA
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Sec-independent protein translocase protein TatA
Pyrimidine nucleoside phosphorylase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cobaltochelatase subunit CobS N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Cation-transporting P-type ATPase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
3-phosphoshikimate 1-carboxyvinyltransferase
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
Ribose-phosphate pyrophosphokinase N-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Plays an important role in substrate specificity
Methionyl-tRNA synthetase anticodon-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA-directed RNA polymerase subunit beta'
Putative Flp pilus-assembly TadG-like N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ATP-dependent dethiobiotin synthetase BioD
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Fimbrial biogenesis outer membrane usher protein
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glutamyl-tRNA(Gln) amidotransferase subunit A
DNA-directed RNA polymerase subunit alpha
Mandelate racemase/muconate lactonizing enzyme C-terminal
Transcription elongation factor GreA/GreB C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Polymerase/histidinol phosphatase N-terminal
Signal transduction histidine kinase HWE region
RND efflux pump membrane fusion protein barrel-sandwich
Phosphocysteine intermediate; for EIIB activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
SUF system FeS cluster assembly SufBD N-terminal
Outer membrane protein assembly factor BamA
Ribosomal RNA small subunit methyltransferase H
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
3-isopropylmalate dehydratase small subunit
NAD(P) transhydrogenase alpha subunit C-terminal
Glycerophosphoryl diester phosphodiesterase membrane
Probable transcriptional regulatory protein Saro_0419
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Disulphide bond isomerase DsbC/G N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycosyl-hydrolase 97 C-terminal oligomerisation
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Signal transduction histidine kinase dimerisation/phosphoacceptor
Polyribonucleotide nucleotidyltransferase
Spore coat protein U domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Type-F conjugative transfer system pilin assembly protein TrbC
TtsA-like Glycoside hydrolase family 108
Anthranilate synthase component I N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Saccharopine dehydrogenase-like C-terminal
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Transcription antitermination protein NusB
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Resolvase/invertase-type recombinase catalytic
Rap1a immunity protein domain-containing protein
DNA replication/recombination mediator RecO N-terminal
NfeD-like C-terminal domain-containing protein
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
CDP-alcohol phosphatidyltransferase C-terminal
Putative pterin-4-alpha-carbinolamine dehydratase
Histidine phosphotransferase ChpT C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Probable potassium transport system protein Kup 2
Polypeptide-transport-associated ShlB-type
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Important for interaction with partner proteins
Cytochrome c-552/4 domain-containing protein
Glyoxalase/fosfomycin resistance/dioxygenase
Endoribonuclease L-PSP/chorismate mutase-like
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
ATP-dependent Clp protease ATP-binding subunit ClpX
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Type II secretion system protein GspG C-terminal
3-keto-disaccharide hydrolase domain-containing protein
Leucyl/phenylalanyl-tRNA--protein transferase
D-galactarate/Altronate dehydratase C-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
tRNA N6-adenosine threonylcarbamoyltransferase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
3-isopropylmalate dehydratase large subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Lipoprotein SmpA/OmlA domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Beta-hexosaminidase bacterial type N-terminal domain-containing protein
Nickel transport system substrate-binding protein