Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
Translation initiation factor 2 subunit alpha
Poly(3-hydroxyalkanoate) polymerase subunit PhaC
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Small ribosomal subunit protein uS15 N-terminal
Polymerase/histidinol phosphatase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Spo11/DNA topoisomerase VI subunit A N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Archaeal glycosylation protein B peripheral
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
SUF system FeS cluster assembly SufBD N-terminal
Translation initiation factor 2 subunit gamma
Major facilitator superfamily (MFS) profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Transcription factor CBF/NF-Y/archaeal histone
DNA-directed RNA polymerase subunit Rpo10
DNA mismatch repair proteins mutS family
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Sodium symporter small subunit predicted
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Cytochrome C biogenesis protein transmembrane
Probable translation initiation factor IF-2
Anthranilate synthase component I N-terminal
Tryptophan synthase beta chain-like PALP
Alanyl-transfer RNA synthetases family profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA-directed RNA polymerase subunit Rpo1C
Glycine cleavage T-protein C-terminal barrel
Pyrroline-5-carboxylate reductase catalytic N-terminal
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sodium/calcium exchanger membrane region
Dihydroneopterin aldolase MtpD C-terminal
DNA-directed RNA polymerase RBP11-like dimerisation
DNA-directed RNA polymerase subunit Rpo11
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Large ribosomal subunit protein uL15/eL18
TRAP C4-dicarboxylate transport system permease DctM subunit
Proliferating cell nuclear antigen PCNA N-terminal
Aspartate carbamoyltransferase regulatory chain
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
4-hydroxy-tetrahydrodipicolinate reductase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cation-transporting P-type ATPase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Probable transposase IS891/IS1136/IS1341
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cytochrome b/b6 C-terminal region profile
Methanogenesis regulatory protein FilR1 middle
Transcription factor NikR nickel binding C-terminal
Type IV secretion system coupling protein TraD DNA-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyruvate phosphate dikinase AMP/ATP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Polysaccharide biosynthesis protein C-terminal
DNA-directed RNA polymerase subunit Rpo12
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-95)
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Heme-copper oxidase subunit III family profile
Tetrahydrodipicolinate-N-succinyltransferase chain A
tRNA (guanine(26)-N(2))-dimethyltransferase
Prepilin type IV endopeptidase peptidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Schiff-base intermediate with acetaldehyde
Nucleolar GTP-binding protein 1 Rossman-fold
DNA polymerase II large subunit DP2 N-terminal
DNA polymerase II large subunit, 1st part
DNA polymerase II large subunit, 2nd part
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Phosphonates import ATP-binding protein PhnC 1
Large ribosomal subunit protein uL6 alpha-beta
Involved in ionization of N3 of dUMP, leading to its activation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cytochrome oxidase subunit II copper A binding
Electron transfer via tryptophanyl radical
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Phosphotransferase system enzyme I N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Geranylgeranylglyceryl phosphate synthase
Schiff-base intermediate with dihydroxyacetone-P
NADH-rubredoxin oxidoreductase C-terminal
rRNA small subunit methyltransferase F RNA-binding PUA-like
DNA polymerase alpha/delta/epsilon subunit B
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Removed in mature form; by autocatalysis
Putative pterin-4-alpha-carbinolamine dehydratase
FAD-dependent oxidoreductase 2 FAD binding
Alpha-D-phosphohexomutase alpha/beta/alpha
MPBQ/MBSQ family SAM-binding methyltransferase profile
Probable chemoreceptor glutamine deamidase CheD
Bacterioopsin transcriptional activator GAF and HTH associated
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Imidazole glycerol phosphate synthase subunit HisF
Glutamyl-tRNA(Gln) amidotransferase subunit E
Peptidase S9 prolyl oligopeptidase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Glutamate-1-semialdehyde 2,1-aminomutase
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
Putative HTH-type transcriptional regulatory protein rrnAC2519
Moybdenum cofactor oxidoreductase dimerisation
Periplasmic copper-binding protein NosD beta helix
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Bacterial type II secretion system protein E
Transcription regulator AsnC/Lrp ligand binding
3-isopropylmalate dehydratase large subunit
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
5-methylthioadenosine/S-adenosylhomocysteine deaminase
RNA polymerase subunit H/Rpb5 C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome b/b6 N-terminal region profile
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein
Phosphate import ATP-binding protein PstB 1
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA-directed RNA polymerase subunit Rpo3
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Actinobacteria/chloroflexi VLRF1 release factor
SAM-dependent methyltransferase TRM5/TYW2-type
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Phosphoadenosine phosphosulphate reductase
3-methyl-2-oxobutanoate hydroxymethyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
Peptide methionine sulphoxide reductase MsrA
tRNA (cytidine(56)-2'-O)-methyltransferase
Shikimate dehydrogenase substrate binding N-terminal
Inosine/uridine-preferring nucleoside hydrolase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Ribosomal RNA large subunit methyltransferase E
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Menaquinone biosynthesis protein MenD middle
Bacterial bifunctional deaminase-reductase C-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Small zinc finger protein HVO-2753-like zinc-binding pocket
Exonuclease VII large subunit C-terminal
Probable glycine cleavage system H protein
Phosphate import ATP-binding protein PstB 2
Large ribosomal subunit protein uL2 C-terminal
No incorporation into translating E.coli polysomes; ribosomes assemble normally. Significantly reduced translational activity.
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Small ribosomal subunit protein eS4 N-terminal
Small ribosomal subunit protein eS4 central region
DNA-directed DNA polymerase family B multifunctional
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
UPF0173 metal-dependent hydrolase rrnAC0300
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Inosine monophosphate cyclohydrolase-like
Cytochrome oxidase subunit II transmembrane region profile
Phosphoribosylformylglycinamidine synthase linker
Phosphoribosylformylglycinamidine synthase subunit PurL
Protein-glutamate methylesterase/protein-glutamine glutaminase
Plays an important role in substrate specificity
Pyridoxal 5'-phosphate synthase subunit PdxT
Large ribosomal subunit protein uL10-like insertion
Inner membrane protein YgaP-like transmembrane
DR2241 4Fe-4S iron-sulfur cluster binding
tRNA (pseudouridine(54)-N(1))-methyltransferase
Nicotinamide-nucleotide adenylyltransferase
Glucose-methanol-choline oxidoreductase C-terminal
Probable inorganic carbon transporter subunit DabA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
6-phosphogluconate dehydrogenase C-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
N-(5'-phosphoribosyl)anthranilate isomerase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Succinate dehydogenase/fumarate reductase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Signal recognition particle 54 kDa protein
Signal recognition particle SRP54 helical bundle
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Translation initiation factor 2 subunit beta
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycerophosphoryl diester phosphodiesterase membrane
Glycerol-1-phosphate dehydrogenase [NAD(P)+]
Signal recognition particle 19 kDa protein
tRNA nucleotidyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
NIF system FeS cluster assembly NifU C-terminal
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
Phosphonates import ATP-binding protein PhnC 2
Urease accessory protein UreH-like transmembrane
NADH:ubiquinone oxidoreductase 30kDa subunit
Glyceraldehyde-3-phosphate dehydrogenase
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Pseudouridine synthase I TruA alpha/beta
Molybdopterin cofactor biosynthesis C (MoaC)
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase
RNA polymerase sigma factor 70 region 4 type 2
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
DNA-directed RNA polymerase subunit Rpo6
Translation elongation factor IF5A C-terminal
ABC transporter substrate-binding protein PnrA-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glucose-methanol-choline oxidoreductase N-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
Probable ribosomal RNA small subunit methyltransferase A
Ribosomal RNA adenine methylase transferase N-terminal
Poly(3-hydroxyalkanoate) polymerase subunit PhaE
GMP synthase [glutamine-hydrolyzing] subunit A
Glutamyl-tRNA(Gln) amidotransferase subunit A
GMP synthase [glutamine-hydrolyzing] subunit B
Imidazole glycerol phosphate synthase subunit HisH
Substrate specificity changes from oxaloacetate to pyruvate.
NIF system FeS cluster assembly NifU N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Nascent polypeptide-associated complex protein
Succinate--CoA ligase [ADP-forming] subunit beta
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
S-adenosyl-L-homocysteine hydrolase NAD binding