Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
CRISPR-associated protein Cas6 C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL6 alpha-beta
Nitrite/Sulfite reductase ferredoxin-like
RNA polymerase sigma factor 70 region 4 type 2
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Organic solvent tolerance-like N-terminal
CobB/CobQ-like glutamine amidotransferase
Type I restriction modification DNA specificity
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Solute-binding protein family 3/N-terminal
General stress protein FMN-binding split barrel
Mannose-6-phosphate isomerase type II C-terminal
Membrane fusion protein biotin-lipoyl like
Chromosomal replication initiator DnaA C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Resolvase/invertase-type recombinase catalytic
Phosphoribosylformylglycinamidine synthase linker
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA replication/recombination mediator RecO N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Polysaccharide chain length determinant N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Galactofuranosyltransferase GlfT2 N-terminal
Polymerase/histidinol phosphatase N-terminal
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Glycosyltransferase 2-like prokaryotic type
Photosystem II cytochrome b559 N-terminal
Photosystem II cytochrome b559 alpha subunit lumenal region
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Tryptophan synthase beta chain-like PALP
Alpha-D-phosphohexomutase alpha/beta/alpha
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
TonB-dependent receptor-like beta-barrel
Large ribosomal subunit protein uL2 C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyl transferase family 28 C-terminal
Vanillate O-demethylase oxygenase-like C-terminal catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
NAD(P) transhydrogenase alpha subunit C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Schiff-base intermediate with acetaldehyde
Sugar fermentation stimulation protein C-terminal
Thiamine pyrophosphate enzyme TPP-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Dienelactone hydrolase domain-containing protein
Restriction endonuclease type I HsdR N-terminal
Increases nucleophilicity of active site Cys
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Photosystem II reaction center protein K
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Thymidylate synthase/dCMP hydroxymethylase
Arginine decarboxylase C-terminal helical
Cytochrome b561 bacterial/Ni-hydrogenase
DNA-directed DNA polymerase family A palm
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cyanobacterial aminoacyl-tRNA synthetase CAAD
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
P-type conjugative transfer protein TrbJ
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Penicillin-binding protein transpeptidase
Sodium symporter small subunit predicted
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Gp5/Type VI secretion system Vgr protein OB-fold
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL15/eL18
CRISPR-associated protein Cmr2 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
6-phosphogluconate dehydrogenase C-terminal
Cell envelope-related transcriptional attenuator
Cation-transporting P-type ATPase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Bacterial type II secretion system protein E
Cytochrome b/b6 N-terminal region profile
Inosine/uridine-preferring nucleoside hydrolase
Peptidase S9 prolyl oligopeptidase catalytic
Schiff-base intermediate with substrate; via pyruvic acid
Photosystem II manganese-stabilizing polypeptide
Cysteine sulfenic acid (-SOH) intermediate
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
NADH:flavin oxidoreductase/NADH oxidase N-terminal
CRISPR system ring nuclease SSO1393-like
Aminoacyl-tRNA synthetase class I anticodon-binding
RNA binding; important for wobble base 34 recognition
HicB-like antitoxin of toxin-antitoxin system
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Translation initiation factor beta propellor-like
Reversibly protonated during proton transport
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Ribulose bisphosphate carboxylase small subunit
Ferredoxin thioredoxin reductase alpha chain
Prokaryotic-type class I peptide chain release factors
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Magnesium-protoporphyrin IX methyltransferase C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Transposase IS116/IS110/IS902 C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Heme-copper oxidase subunit III family profile
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Sodium/calcium exchanger membrane region
Glycosyltransferase family 28 N-terminal
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Plastid lipid-associated protein/fibrillin conserved
Pseudouridine synthase I TruA alpha/beta
Translation elongation factor P/YeiP central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Important for beta-aspartyl-AMP intermediate formation
Protein O-mannosyl-transferase C-terminal four TM
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Cob(I)alamin adenosyltransferase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Homocysteine biosynthesis enzyme sulfur-incorporation
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Glucosamine/galactosamine-6-phosphate isomerase
RlpA-like protein double-psi beta-barrel
Small ribosomal subunit protein uS4 N-terminal
Release factor glutamine methyltransferase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Acetylserotonin O-methyltransferase dimerisation
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Probable transposase IS891/IS1136/IS1341
Inward rectifier potassium channel C-terminal
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphoadenosine phosphosulphate reductase
Photosystem I PsaL reaction centre subunit XI
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Cytochrome b/b6 C-terminal region profile
Shikimate dehydrogenase substrate binding N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Interaction with polymerase core subunit RpoC
Polypeptide-transport-associated ShlB-type
Fatty acid synthase subunit PfaD N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Involved in allosteric activation by GTP
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Carbamoyl-phosphate synthase small subunit N-terminal
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
Pyruvate phosphate dikinase AMP/ATP-binding
Type II secretion system protein GspE N-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Cytochrome C biogenesis protein transmembrane
Acyl-CoA dehydrogenase/oxidase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycosyl transferase family 3 N-terminal
Anaphase-promoting complex subunit 4-like WD40
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Schiff-base intermediate with substrate; via topaquinone
Glycoside hydrolase family 57 N-terminal
Septum formation inhibitor MinC C-terminal
Peptide methionine sulphoxide reductase MsrA
RNA 2-O ribose methyltransferase substrate binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Type I restriction enzyme R protein N-terminal
Prepilin type IV endopeptidase peptidase
Proton acceptor; for glutaminase activity
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Photosystem I reaction center subunit III
ABC-type uncharacterised transport system
WGxxGxxG-CTERM domain-containing protein
Could play a key role in the communication between the regulatory and the substrate sites
Survival protein SurE-like phosphatase/nucleotidase
Nucleophile; cysteine thiosulfonate intermediate
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Increases the nucleophilicity of the active site Cys
Alanyl-transfer RNA synthetases family profile
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Ionotropic glutamate receptor C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Urease accessory protein UreH-like transmembrane
Magnesium chelatase subunit H N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Essential for prephenate dehydratase activity
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Membrane insertase YidC/Oxa/ALB C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA mismatch repair proteins mutS family
Histidine-specific methyltransferase SAM-dependent
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Toxin co-regulated pilus biosynthesis protein Q C-terminal domain-containing protein
Glycosyl hydrolases family 2 sugar binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Methionyl-tRNA synthetase anticodon-binding
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type IV secretion system coupling protein TraD DNA-binding
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NAD(P)H-quinone oxidoreductase subunit 2 N-terminal
Damage-control phosphatase ARMT1-like metal-binding
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
PhoD-like phosphatase metallophosphatase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Putative glycogen debranching enzyme N-terminal
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Molybdopterin cofactor biosynthesis C (MoaC)
Beta-lactamase hydrolase-like protein phosphatase-like
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Quercetin 2,3-dioxygenase C-terminal cupin
Large ribosomal subunit protein bL25 L25
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Anthranilate synthase component I N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Positions MEP for the nucleophilic attack
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glucose/Sorbosone dehydrogenase domain-containing protein