Glycosyltransferase subfamily 4-like N-terminal
FAD-dependent oxidoreductase 2 FAD binding
YbaK/aminoacyl-tRNA synthetase-associated
AB hydrolase-1 domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
O-(3'-phospho-DNA)-tyrosine intermediate
RNA 2-O ribose methyltransferase substrate binding
Major facilitator superfamily (MFS) profile
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Plays an important role in substrate specificity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Heme-copper oxidase subunit III family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosomal RNA small subunit methyltransferase H
Pyrimidine/purine nucleoside phosphorylase
TtsA-like Glycoside hydrolase family 108
Solute-binding protein family 3/N-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Gamma-butyrobetaine hydroxylase-like N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tryptophan synthase beta chain-like PALP
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Membrane fusion protein biotin-lipoyl like
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome b561 bacterial/Ni-hydrogenase
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Bacterial type II secretion system protein E
TRAP C4-dicarboxylate transport system permease DctM subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Ionotropic glutamate receptor C-terminal
100-fold decrease in the catalytic efficiency of the aldol cleavage reaction. Dramatic reduction in acetaldehyde and propanaldehyde channeling efficiency by more than 70%.
32-fold reduction in the catalytic efficiency with acetaldehyde as substrate of the aldol addition reaction, but no change in the catalytic efficiency using propanaldehyde; thus, exhibits a 40-fold preference for propanaldehyde over acetaldehyde.
4000-fold decrease in the catalytic efficiency of the aldol cleavage reaction.
Able to channel acetaldehyde but not the larger propanaldehyde.
Able to channel butyraldehyde (with less efficiency than wild-type) but not its isomer isobutyraldehyde.
As the wild-type enzyme, exhibits similar catalytic efficiency with acetaldehyde or propanaldehyde as substrate in the aldol addition reaction but displays higher catalytic efficiency with longer aldehydes (50-fold increase using pentaldehyde). Shows a reduction in aldehyde channeling efficiency by 30%.
Displays a reduction in aldehyde channeling efficiency of about 20%.
Important for aldehyde specificity, and governs stereochemical control
Important for aldehyde specificity; governs substrate alkyl chain length
Loss of aldolase activity (with either enantiomer of HOPA), but retains some decarboxylase activity for the smaller oxaloacetate substrate. In the retro-aldol cleavage reaction, is inactive toward 4(S)-HOPA but is active toward 4(R)-HOPA, albeit with a great reduction in catalytic efficiency, and in the aldol addition reaction, produces also exclusively the 4(R)-enantiomer; when associated with F-290.
Loss of stereochemical control as the mutant is able to catalyze the aldol cleavage of substrates with both R and S configurations at C4 with similar kinetic parameters. 3.5-fold decrease in the catalytic efficiency of the aldol cleavage reaction.
Loss of stereochemical control as the mutant is able to catalyze the aldol cleavage of substrates with both R and S configurations at C4 with similar kinetic parameters. 3.5-fold decrease in the catalytic efficiency of the aldol cleavage reaction. Reduction in aldehyde channeling efficiency by more than 30%. In the retro-aldol cleavage reaction, is inactive toward 4(S)-HOPA but is active toward 4(R)-HOPA, albeit with a great reduction in catalytic efficiency, and in the aldol addition reaction, produces also exclusively the 4(R)-enantiomer; when associated with N-87 or W-87.
Unable to channel either acetaldehyde or propanaldehyde.
Acyl-CoA dehydrogenase/oxidase C-terminal
Polysaccharide chain length determinant N-terminal
D-(-)-3-hydroxybutyrate oligomer hydrolase
Putative 3-methyladenine DNA glycosylase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
RNA binding; important for wobble base 34 recognition
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Reversibly protonated during proton transport
Signal recognition particle SRP54 helical bundle
Pyridoxamine 5'-phosphate oxidase putative
Cucumopine synthase C-terminal helical bundle
Caspase family p20 domain-containing protein
Schiff-base intermediate with substrate; via pyruvic acid
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cyclic pyranopterin monophosphate synthase
Phosphatidic acid phosphatase type 2/haloperoxidase
Type 2A encapsulin shell protein SrpI-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Putative regulatory protein FmdB Zinc ribbon
Saccharopine dehydrogenase-like C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
TonB-dependent receptor-like beta-barrel
Transposase IS116/IS110/IS902 C-terminal
High potential iron-sulfur proteins family profile
Moybdenum cofactor oxidoreductase dimerisation
Protein-glutamate methylesterase/protein-glutamine glutaminase
Polysaccharide biosynthesis protein CapD-like
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Glutamyl-tRNA(Gln) amidotransferase subunit A
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Ribulose bisphosphate carboxylase small subunit
TIGR03759 family integrating conjugative element protein
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Probable septum site-determining protein MinC
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glucose-methanol-choline oxidoreductase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Interaction with polymerase core subunit RpoC
ATP-dependent Clp protease proteolytic subunit 2
Putative Flp pilus-assembly TadG-like N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Rap1a immunity protein domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Nitrogenase molybdenum-iron protein beta chain N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Virulence factor membrane-bound polymerase C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Ribosomal RNA large subunit methyltransferase E
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Helix-hairpin-helix DNA-binding motif class 1
Taurine import ATP-binding protein TauB 3
Potassium-transporting ATPase KdpC subunit
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
Putative iron-sulfur cluster insertion protein ErpA 2
Phosphocysteine intermediate; for EIIB activity
Type II secretion system protein GspG C-terminal
DNA polymerase III subunit delta C-terminal
C-type lysozyme inhibitor domain-containing protein
2-fold decrease in catalytic efficiency.
4- to 7-fold decrease in catalytic efficiency with aldehydes three to four carbons in length. Does not significantly reduce the channeling efficiency of the enzyme complex toward acetaldehyde or propanaldehyde.
5- to 16-fold decrease in catalytic efficiency with aldehydes two to four carbons in length. Exhibits 59% of wild-type acetaldehyde channeling efficiency.
5-fold decrease in affinity for acetaldehyde. Increase in affinity for butyraldehyde and pentaldehyde, leading to a 9- and 20-fold increase in catalytic efficiency with butyraldehyde and pentaldehyde as substrate, respectively. Exhibits 84% of wild-type acetaldehyde channeling efficiency.
Displays significant reduction in the level of allosteric activation of the aldol cleavage reaction by BphI.
Does not significantly reduce the channeling efficiency of the enzyme complex toward acetaldehyde or propanaldehyde.
Exhibits preferences for aldehydes similar as wild-type. Exhibits about 80% of wild-type acetaldehyde channeling efficiency. Displays significant reduction in the level of allosteric activation of the aldol cleavage reaction by BphI.
Loss of catalytic activity. Still able to bind NAD(+), however with much lower affinity.
Responsible for governing aldehyde substrate chain length specificity
Polypeptide-transport-associated ShlB-type
Methionine import ATP-binding protein MetN 2
Sec-independent protein translocase protein TatB
Taurine import ATP-binding protein TauB 1
DNA-directed RNA polymerase subunit beta'
Pyruvate/ketoisovalerate oxidoreductase catalytic
Periplasmic copper-binding protein NosD beta helix
Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Could be important to modulate the pK values of the two catalytic cysteine residues
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
HicB-like antitoxin of toxin-antitoxin system
EfeO-type cupredoxin-like domain-containing protein
Oxidoreductase molybdopterin-binding domain-containing protein
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Phosphoadenosine phosphosulphate reductase
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
3-phosphoshikimate 1-carboxyvinyltransferase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Aliphatic sulfonates import ATP-binding protein SsuB 1
Proton acceptor; specific for R-mandelate
Proton acceptor; specific for S-mandelate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Probable chemoreceptor glutamine deamidase CheD
SGNH hydrolase-type esterase domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Aliphatic sulfonates import ATP-binding protein SsuB 2
Putative glycogen debranching enzyme N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Aconitase A/isopropylmalate dehydratase small subunit swivel
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
ATP synthase F1 complex delta/epsilon subunit N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Enoyl-[acyl-carrier-protein] reductase [NADH]
Plays an important role in discriminating NADH against NADPH
Glycosyl transferase family 3 N-terminal
ABC-type glycine betaine transport system substrate-binding
Probable potassium transport system protein Kup
NADH:ubiquinone oxidoreductase 30kDa subunit
O-(5'-phospho-DNA)-tyrosine intermediate
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cytochrome oxidase subunit II copper A binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Histidine-specific methyltransferase SAM-dependent
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for interaction with partner proteins
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Taurine import ATP-binding protein TauB 2
Interacts with tRNA; defines subfamily-specific binding signature
Involved in tetramerization or stability of the tetramer
tRNA N6-adenosine threonylcarbamoyltransferase
Glycine cleavage T-protein C-terminal barrel
Involved in Mg(2+) ion dislocation from EF-Tu
Gp5/Type VI secretion system Vgr protein OB-fold
Adaptive response protein AidB N-terminal
Seems to be a necessary countercharge to the potassium cations
Polymerase/histidinol phosphatase N-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
CobB/CobQ-like glutamine amidotransferase
Penicillin-binding protein transpeptidase
UDP-N-acetylmuramoylalanine--D-glutamate ligase
ABC transporter substrate-binding protein PnrA-like
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
DNA-directed RNA polymerase subunit beta
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
NIF system FeS cluster assembly NifU N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Cysteine sulfenic acid (-SOH) intermediate
DNA-directed DNA polymerase family A palm
Isocitrate dehydrogenase kinase/phosphatase
Resolvase/invertase-type recombinase catalytic
Phosphoribosylformylglycinamidine cyclo-ligase
Uncharacterized HTH-type transcriptional regulator BphR
Dinitrogenase iron-molybdenum cofactor biosynthesis
ATP-dependent Clp protease proteolytic subunit 1
Gly-cisPro motif, important for rejection of L-amino acids
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Putative HTH-type transcriptional regulator
Putative ribose/galactose/methyl galactoside import ATP-binding protein
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
UDP-3-O-acylglucosamine N-acyltransferase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Putative phosphoenolpyruvate synthase regulatory protein
Pyruvate dehydrogenase E1 component middle
Prokaryotic-type class I peptide chain release factors
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Inward rectifier potassium channel C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
CagE TrbE VirB component of type IV transporter system central
ATP-dependent Clp protease adapter protein ClpS
Cytochrome oxidase subunit II transmembrane region profile
2-dehydro-3-deoxyphosphooctonate aldolase
6-phosphogluconate dehydrogenase C-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Outer membrane protein assembly factor BamA
Aliphatic sulfonates import ATP-binding protein SsuB 3
Anti-bacteriophage protein A/HamA C-terminal
Electron transfer via tryptophanyl radical
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Chromosomal replication initiator protein DnaA
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Putative oxidoreductase/dehydrogenase Rossmann-like
Proton acceptor; for glutaminase activity
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
TRAP transporter solute receptor, TAXI family
Peptide methionine sulphoxide reductase MsrA
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
ABC transporter, periplasmic ligand binding protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Superoxide dismutase copper/zinc binding
Glucosamine/galactosamine-6-phosphate isomerase
Type II secretion system protein GspI C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Guanylate kinase/L-type calcium channel beta subunit
ATP-dependent Clp protease ATP-binding subunit ClpX
Pyruvate phosphate dikinase AMP/ATP-binding
Exonuclease VII large subunit C-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Putative pterin-4-alpha-carbinolamine dehydratase
Ribosomal protein uS12 methylthiotransferase RimO
Ribonucleotide reductase large subunit C-terminal
Flagellar hook-length control protein-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
Leucyl/phenylalanyl-tRNA--protein transferase
Essential for prephenate dehydratase activity
Flagellar motor switch protein FliN-like C-terminal
Transcription antitermination protein NusB
Transglycosylase SLT domain-containing protein
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Inosine/uridine-preferring nucleoside hydrolase
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase
Catalytic role in ketonization of the dienol substrate (substrate destabilization)
Phosphonates import ATP-binding protein PhnC
Biphenyl dioxygenase system ferredoxin--NAD(+) reductase component
Xaa-Pro dipeptidyl-peptidase-like domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA small subunit methyltransferase A
DNA topoisomerase I catalytic core eukaryotic-type
Required for dimer formation and molybdate binding
ATP phosphoribosyltransferase regulatory subunit
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Heme-containing CO-sensing transcriptional regulator RcoM 2
Iron-sulfur cluster assembly protein CyaY
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Cation-transporting P-type ATPase N-terminal
DNA-directed RNA polymerase subunit alpha
N6 adenine-specific DNA methyltransferase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Uncharacterized BphX-like protein Bxeno_C1129
Prepilin type IV endopeptidase peptidase
Mannose-6-phosphate isomerase type II C-terminal
Crossover junction endodeoxyribonuclease RuvC
Dual-specificity RNA methyltransferase RlmN
Peptidase S9 prolyl oligopeptidase catalytic
Succinate--CoA ligase [ADP-forming] subunit beta
Ribosomal RNA large subunit methyltransferase H
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADPH-dependent 7-cyano-7-deazaguanine reductase
Gamma-glutamylcyclotransferase AIG2-like
Periplasmic nitrate reductase, electron transfer subunit
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like stalk
AraC-type arabinose-binding/dimerisation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
N-succinylglutamate 5-semialdehyde dehydrogenase
Type I restriction modification DNA specificity
Water stress and hypersensitive response
Electron transfer flavoprotein alpha subunit C-terminal
Holliday junction branch migration complex subunit RuvA
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
ATP-dependent protease ATPase subunit HslU
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC
Putative membrane protein insertion efficiency factor
DnaJ homologue subfamily C member 28 conserved
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Putative type VI secretion system Rhs element associated Vgr
3-deoxy-manno-octulosonate cytidylyltransferase
Ribosomal RNA small subunit methyltransferase G
Cobalt-precorrin-5B C(1)-methyltransferase
Sec-independent protein translocase protein TatA
Sodium symporter small subunit predicted
sn-glycerol-3-phosphate import ATP-binding protein UgpC
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Disulphide bond isomerase DsbC/G N-terminal
Sodium/calcium exchanger membrane region
Moves into active site upon enzyme activation, plays a role in electron transfer
1-aminocyclopropane-1-carboxylate deaminase
UDP-N-acetylenolpyruvoylglucosamine reductase
Required for zinc-mediated homotetramerization and catalytic activity
Lytic transglycosylase superhelical linker
Integrating conjugative element protein pill, pfgi-1
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase
Catalyzes the tautomerisation of HOPDA. Extremely low hydrolase activity; when associated with A-265.
Unable to catalyze the tautomerisation of HOPDA. Extremely low hydrolase activity; when associated with A-112.
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Glycine-zipper-containing OmpA-like membrane
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Methionine import ATP-binding protein MetN 1
Outer membrane protein beta-barrel domain-containing protein
YMGG-like Gly-zipper domain-containing protein
Endoribonuclease L-PSP/chorismate mutase-like
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Biosynthetic peptidoglycan transglycosylase
Putative conjugal transfer nickase/helicase TraI C-terminal
Nitrogenase-stabilizing/protective protein NifW
DNA-directed RNA polymerase subunit omega
Anthranilate synthase component I N-terminal
ABC-type transport auxiliary lipoprotein component
Small ribosomal subunit biogenesis GTPase RsgA
1-deoxy-D-xylulose 5-phosphate reductoisomerase
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Holliday junction branch migration complex subunit RuvB
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Oxygen-dependent coproporphyrinogen-III oxidase
Glutamate synthase alpha subunit C-terminal
Twin-arginine translocation pathway signal sequence domain-containing protein
Cell division topological specificity factor
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Heme-containing CO-sensing transcriptional regulator RcoM 1
Loss of ability to bind heme. Loss of ability to respond to CO, presenting constitutive activity.
Loss of ability to bind heme. Loss of activity.
Much higher affinity for CO. Loss of activity. No effect on heme incorporation.
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Thymidylate synthase/dCMP hydroxymethylase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Type I phosphodiesterase/nucleotide pyrophosphatase
ABC-type transport auxiliary lipoprotein component domain-containing protein
Thiol:disulfide interchange protein DsbD
Schiff-base intermediate with acetoacetate
Ribulose bisphosphate carboxylase large chain
Bifunctional purine biosynthesis protein PurH
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nitrite/Sulfite reductase ferredoxin-like
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Large-conductance mechanosensitive channel
Phosphate import ATP-binding protein PstB
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Alanyl-transfer RNA synthetases family profile
Cytochrome c biogenesis ATP-binding export protein CcmA
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-269)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-91)
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Glutamate-1-semialdehyde 2,1-aminomutase
Aspartate/homoserine dehydrogenase NAD-binding
Alpha-glycerophosphate oxidase C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Proline utilization A proline dehydrogenase N-terminal
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Imidazole glycerol phosphate synthase subunit HisF
Beta-lactamase hydrolase-like protein phosphatase-like
2-aminoethylphosphonate--pyruvate transaminase 1
Putative iron-sulfur cluster insertion protein ErpA 1
Release factor glutamine methyltransferase N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Transcription factor NikR nickel binding C-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Peptide methionine sulfoxide reductase MsrA
Lipoprotein-releasing system ATP-binding protein LolD
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Methylguanine DNA methyltransferase ribonuclease-like
3-methyl-2-oxobutanoate hydroxymethyltransferase
Arabinose import ATP-binding protein AraG
Ubiquinone biosynthesis O-methyltransferase
Probable transcriptional regulatory protein Bxeno_A1185
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Formate-dependent phosphoribosylglycinamide formyltransferase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
PHA accumulation regulator DNA-binding N-terminal
Biphenyl dioxygenase system ferredoxin subunit