NAD(P) transhydrogenase alpha subunit C-terminal
Spermidine/putrescine import ATP-binding protein PotA
Aminoacyl-transfer RNA synthetases class-II family profile
Phosphoribosylformylglycinamidine synthase linker
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
3-isopropylmalate dehydratase large subunit 2
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
NIF system FeS cluster assembly NifU N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Ribose import ATP-binding protein RbsA 2
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Endoribonuclease L-PSP/chorismate mutase-like
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Probable dual-specificity RNA methyltransferase RlmN
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Major facilitator superfamily (MFS) profile
Cytochrome C biogenesis protein transmembrane
Pyridoxal 5'-phosphate synthase subunit PdxT
Putative regulatory protein FmdB Zinc ribbon
Bacterial spore germination immunoglobulin-like
Bacterial spore germination immunoglobulin-like domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Prokaryotic-type class I peptide chain release factors
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Polysaccharide biosynthesis protein C-terminal
Crossover junction endodeoxyribonuclease RuvC
Mandelate racemase/muconate lactonizing enzyme C-terminal
Chromosomal replication initiator DnaA C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
FAD-dependent oxidoreductase 2 FAD binding
Glycine cleavage T-protein C-terminal barrel
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
RNA 2-O ribose methyltransferase substrate binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Proton acceptor; for glutaminase activity
ATP phosphoribosyltransferase regulatory subunit
Polyribonucleotide nucleotidyltransferase
Pyrimidine nucleoside phosphorylase C-terminal
Transcription regulator AsnC/Lrp ligand binding
Lysidine-tRNA(Ile) synthetase C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
UPF0173 metal-dependent hydrolase Rxyl_1261
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyridoxamine 5'-phosphate oxidase putative
Peptidase S9 prolyl oligopeptidase catalytic
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Myo-inositol-1-phosphate synthase GAPDH-like
3-isopropylmalate dehydratase small subunit
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
DR2241 4Fe-4S iron-sulfur cluster binding
SUF system FeS cluster assembly SufBD N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Tryptophan synthase beta chain-like PALP
Moybdenum cofactor oxidoreductase dimerisation
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Sodium/calcium exchanger membrane region
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
CobB/CobQ-like glutamine amidotransferase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Cytochrome b/b6 C-terminal region profile
Membrane insertase YidC/Oxa/ALB C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Phosphatidic acid phosphatase type 2/haloperoxidase
Phosphocysteine intermediate; for EIIB activity
Essential for prephenate dehydratase activity
Interaction with polymerase core subunit RpoC
Ribose import ATP-binding protein RbsA 1
RlpA-like protein double-psi beta-barrel
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Cytochrome b/b6 N-terminal region profile
Penicillin-binding protein transpeptidase
Leucyl/phenylalanyl-tRNA--protein transferase
Formamidopyrimidine-DNA glycosylase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Probable transcriptional regulatory protein Rxyl_1318
N-acetyl-gamma-glutamyl-phosphate reductase
PrcB C-terminal domain-containing protein
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Histidine-specific methyltransferase SAM-dependent
Bacterial type II secretion system protein E
Cobalt-precorrin-5B C(1)-methyltransferase
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Poly-beta-hydroxybutyrate polymerase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
PhoD-like phosphatase metallophosphatase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
RNA polymerase sigma factor 70 region 4 type 2
Type I phosphodiesterase/nucleotide pyrophosphatase
Polysaccharide chain length determinant N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
CRISPR system ring nuclease SSO1393-like
Glucosamine/galactosamine-6-phosphate isomerase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
DNA-directed DNA polymerase family A palm
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Redox-sensing transcriptional repressor Rex
Transcription antitermination protein NusB
UDP-N-acetylmuramoylalanine--D-glutamate ligase
Cation-transporting P-type ATPase N-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Increases nucleophilicity of active site Cys
Inosine/uridine-preferring nucleoside hydrolase
Gram-positive cocci surface proteins LPxTG
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Glycoside hydrolase family 31 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase H
CRISPR-associated protein Cas6 C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pseudouridine synthase I TruA alpha/beta
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Gram-positive cocci surface proteins LPxTG domain-containing protein
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ATP-dependent Clp protease proteolytic subunit
NIF system FeS cluster assembly NifU C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Could be important to modulate the pK values of the two catalytic cysteine residues
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Holliday junction branch migration complex subunit RuvB
Holliday junction branch migration complex subunit RuvA
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
DNA-directed RNA polymerase subunit beta'
L-seryl-tRNA selenium transferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Phosphotransferase system enzyme I N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Succinate--CoA ligase [ADP-forming] subunit beta
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Ribosomal RNA small subunit methyltransferase A
Involved in allosteric activation by GTP
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
ABC-type glycine betaine transport system substrate-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Alpha-glycerophosphate oxidase C-terminal
Probable nicotinate-nucleotide adenylyltransferase
Putative membrane protein insertion efficiency factor
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
D-galactarate/Altronate dehydratase C-terminal
Putative pterin-4-alpha-carbinolamine dehydratase
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
3-isopropylmalate dehydratase large subunit 1
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
RNA binding; important for wobble base 34 recognition
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Bifunctional IPC transferase and DIPP synthase
Na+/H+ antiporter MnhB subunit-related protein
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Alanyl-transfer RNA synthetases family profile
Siroheme decarboxylase AsnC-like ligand binding
Carbamoyl-phosphate synthase large chain
Ribosomal RNA small subunit methyltransferase E methyltransferase
Prepilin type IV endopeptidase peptidase
DNA mismatch repair proteins mutS family
NADH:ubiquinone oxidoreductase 30kDa subunit
4-hydroxy-tetrahydrodipicolinate reductase
Glutamyl-tRNA(Gln) amidotransferase subunit A
YbaK/aminoacyl-tRNA synthetase-associated
N-acetylmuramic acid 6-phosphate etherase
Involved in Mg(2+) ion dislocation from EF-Tu
Carbamoyl-phosphate synthase small subunit N-terminal
N-(5'-phosphoribosyl)anthranilate isomerase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Gly-cisPro motif, important for rejection of L-amino acids
Mannose-6-phosphate isomerase type II C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Right handed beta helix domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding