Solute-binding protein family 3/N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Catalytic role in ketonization of the dienol substrate (substrate destabilization)
Mandelate racemase/muconate lactonizing enzyme C-terminal
Reversibly protonated during proton transport
Could be important to modulate the pK values of the two catalytic cysteine residues
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Glutamate synthase alpha subunit C-terminal
Putative regulatory protein FmdB Zinc ribbon
Carboxypeptidase regulatory-like domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Bacterial type II secretion system protein E
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Phosphocysteine intermediate; for EIIB activity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Exonuclease VII large subunit C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Ionotropic glutamate receptor C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase 30kDa subunit
Helix-hairpin-helix DNA-binding motif class 1
Helix-hairpin-helix DNA-binding motif class 1 domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Surface antigen domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Outer membrane protein assembly factor BamB
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Membrane fusion protein biotin-lipoyl like
Interaction with polymerase core subunit RpoC
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
High potential iron-sulfur proteins family profile
O-(phosphoribosyl dephospho-coenzyme A)serine
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Ribonucleotide reductase large subunit C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ABC transporter substrate-binding protein PnrA-like
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA topoisomerase I catalytic core eukaryotic-type
Cucumopine synthase C-terminal helical bundle
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
RNA polymerase sigma factor 70 region 4 type 2
Transposase IS116/IS110/IS902 C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Guanylate kinase/L-type calcium channel beta subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Peptidase S9 prolyl oligopeptidase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Prepilin type IV endopeptidase peptidase
Penicillin-binding protein transpeptidase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
S-adenosyl-L-homocysteine hydrolase NAD binding
Bacterial collagen-like protein middle domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Choloylglycine hydrolase/NAAA C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar hook-basal body complex protein FliE
Glycine cleavage T-protein C-terminal barrel
Proline utilization A proline dehydrogenase N-terminal
Type II secretion system protein GspI C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Integral membrane protein YccS N-terminal
HicB-like antitoxin of toxin-antitoxin system
Prokaryotic-type class I peptide chain release factors
Tryptophan synthase beta chain-like PALP
ATP synthase F1 complex delta/epsilon subunit N-terminal
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Gamma-glutamylcyclotransferase AIG2-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Phosphotransferase system enzyme I N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Signal recognition particle SRP54 helical bundle
Heme-copper oxidase subunit III family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Tetrahydrodipicolinate-N-succinyltransferase chain A
AB hydrolase-1 domain-containing protein
ABC-type transport auxiliary lipoprotein component
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Water stress and hypersensitive response
Moves into active site upon enzyme activation, plays a role in electron transfer
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ABC-type glycine betaine transport system substrate-binding
NADH:ubiquinone oxidoreductase chain 4 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Polypeptide-transport-associated ShlB-type
Translation elongation factor P/YeiP central
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
40-residue YVTN family beta-propeller repeat-containing protein
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Electron transfer via tryptophanyl radical
TonB-dependent receptor-like beta-barrel
Type II secretion system protein GspG C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Saccharopine dehydrogenase-like C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Putative type VI secretion system Rhs element associated Vgr
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cytochrome b561 bacterial/Ni-hydrogenase
DNA-3-methyladenine glycosylase AlkA N-terminal
Plays an important role in discriminating NADH against NADPH
Sporulation stage II protein D amidase enhancer LytB N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Sodium/calcium exchanger membrane region
Ysc84 actin-binding domain-containing protein
Required for dimer formation and molybdate binding
DNA-directed DNA polymerase family A palm
Release factor glutamine methyltransferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Inward rectifier potassium channel C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ribulose bisphosphate carboxylase small subunit
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Glycosyltransferase subfamily 4-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
NIF system FeS cluster assembly NifU N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
YMGG-like Gly-zipper domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Pyruvate dehydrogenase E1 component middle
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyruvate phosphate dikinase AMP/ATP-binding
TtsA-like Glycoside hydrolase family 108
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Putative glycogen debranching enzyme N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Type VI secretion system IcmF C-terminal
Type 2A encapsulin shell protein SrpI-like
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Alanyl-transfer RNA synthetases family profile
D-galactarate/Altronate dehydratase C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Electron transfer flavoprotein alpha subunit C-terminal
Anthranilate synthase component I N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
N-end rule aminoacyl transferase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Twin-arginine translocation pathway signal sequence domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL15/eL18
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Plays an important role in substrate specificity
Could play a key role in the communication between the regulatory and the substrate sites
Aspartate/homoserine dehydrogenase NAD-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Involved in tetramerization or stability of the tetramer
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL6 alpha-beta
Glycine-zipper-containing OmpA-like membrane
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
RNA binding; important for wobble base 34 recognition
Peptide methionine sulphoxide reductase MsrA
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Polysaccharide chain length determinant N-terminal
Important for interaction with partner proteins
Histidine-specific methyltransferase SAM-dependent
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DnaJ homologue subfamily C member 28 conserved
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Pyridoxamine 5'-phosphate oxidase putative
PHA accumulation regulator DNA-binding N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glucose-methanol-choline oxidoreductase C-terminal
NIF system FeS cluster assembly NifU C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Outer membrane protein beta-barrel domain-containing protein
Essential for prephenate dehydratase activity
Outer membrane protein assembly factor BamA
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Sodium symporter small subunit predicted
Small ribosomal subunit protein uS4 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Seems to be a necessary countercharge to the potassium cations
Lysozyme inhibitor LprI N-terminal domain-containing protein
ABC transporter type 1 GsiC-like N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Carbamoyl-phosphate synthase small subunit N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Pseudouridine synthase I TruA alpha/beta
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Antitoxin Xre/MbcA/ParS-like toxin-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Oxidoreductase molybdopterin-binding domain-containing protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Flagellar hook-length control protein-like C-terminal
RNA 2-O ribose methyltransferase substrate binding
Cation-transporting P-type ATPase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Potassium-transporting ATPase KdpC subunit
Shikimate dehydrogenase substrate binding N-terminal
Disulphide bond isomerase DsbC/G N-terminal