TonB-dependent receptor-like beta-barrel
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
SUF system FeS cluster assembly SufBD N-terminal
DNA mismatch repair proteins mutS family
Peptide methionine sulphoxide reductase MsrA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Signal transduction histidine kinase internal region
RNA polymerase sigma factor 70 region 4 type 2
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
Exonuclease VII large subunit C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NIF system FeS cluster assembly NifU C-terminal
Anthranilate synthase component I N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
P pilus assembly protein, chaperone PapD
RND efflux pump membrane fusion protein barrel-sandwich
Proton acceptor; for glutaminase activity
Nucleophile; cysteine thiosulfonate intermediate
6-phosphogluconate dehydrogenase NADP-binding
Peptidase M1 membrane alanine aminopeptidase
Fibrobacter succinogenes major paralogous domain-containing protein
Lipocalin-like domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Outer membrane receptor for ferrienterochelin and colicins
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:ubiquinone oxidoreductase 30kDa subunit
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Glycosyl transferase family 3 N-terminal
RNA 2-O ribose methyltransferase substrate binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Carboxypeptidase regulatory-like domain-containing protein
Penicillin-binding protein transpeptidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Outer membrane protein beta-barrel domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Plays an important role in discriminating NADH against NADPH
Glycosyltransferase subfamily 4-like N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Polysaccharide chain length determinant N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cysteine sulfenic acid (-SOH) intermediate
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Restriction endonuclease type II EcoRII C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
FAD-dependent oxidoreductase 2 FAD binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Thiol:disulfide interchange protein DsbD N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Plays an important role in substrate specificity
Ribose-phosphate pyrophosphokinase N-terminal
Bacteroidetes-Associated Carbohydrate-binding Often N-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Heme-copper oxidase subunit III family profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyridoxamine 5'-phosphate oxidase putative
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Polymerase/histidinol phosphatase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL15/eL18
Aspartate/homoserine dehydrogenase NAD-binding
RNA binding; important for wobble base 34 recognition
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Cytochrome C biogenesis protein transmembrane
Glycine cleavage T-protein C-terminal barrel
Beta-hexosaminidase bacterial type N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Positions MEP for the nucleophilic attack
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Surface glycan-binding protein B xyloglucan binding
Surface glycan-binding protein B xyloglucan binding domain-containing protein
General stress protein FMN-binding split barrel
Plays an important role in maintaining the position of the catalytic nucleophile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Polysaccharide biosynthesis protein CapD-like
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Membrane insertase YidC/Oxa/ALB C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Tryptophan synthase beta chain-like PALP
Solute-binding protein family 3/N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
TonB-dependent receptor-like beta-barrel domain-containing protein
Type I restriction enzyme R protein N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Urease accessory protein UreH-like transmembrane
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
TonB C-terminal domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Electron transfer via tryptophanyl radical
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Type IV secretion system coupling protein TraD DNA-binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Glycoside hydrolase GH146 substrate-binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Transition state stabilizer; via amide nitrogen
Putative auto-transporter adhesin head GIN
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Helix-hairpin-helix DNA-binding motif class 1
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Butirosin biosynthesis protein H N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Prokaryotic-type class I peptide chain release factors
Homogentisate 1,2-dioxygenase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
N6 adenine-specific DNA methyltransferase N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Biopterin-dependent aromatic amino acid hydroxylase family profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyl hydrolase family 95 N-terminal domain-containing protein
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
ABC-type uncharacterised transport system
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Important for beta-aspartyl-AMP intermediate formation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL6 alpha-beta
Myo-inositol-1-phosphate synthase GAPDH-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein uL2 C-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glycoside hydrolase family 42 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycoside hydrolase family 13 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
TonB-linked outer membrane protein, SusC/RagA family
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Carbamoyl-phosphate synthase small subunit N-terminal
Putative beta-lactamase-inhibitor-like PepSY-like
Transglutaminase-like domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Phosphoadenosine phosphosulphate reductase
Cation-transporting P-type ATPase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ribosomal RNA adenine methylase transferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Chromosomal replication initiator DnaA C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Thiopeptide-type bacteriocin biosynthesis
Phosphatidylglycerol lysyltransferase C-terminal
ParB-related ThiF-related cassette protein E
Glycosyl-hydrolase 97 C-terminal oligomerisation
UDP N-acetylglucosamine O-acyltransferase C-terminal
Chitobiase/beta-hexosaminidases N-terminal
Polysaccharide biosynthesis protein C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
N-sulphoglucosamine sulphohydrolase C-terminal
tRNA pseudouridylate synthase B C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Trigger factor ribosome-binding bacterial
DNA-directed DNA polymerase family A palm
Alpha-glycerophosphate oxidase C-terminal
Small ribosomal subunit protein uS4 N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Phosphoribosylformylglycinamidine synthase
Inner membrane protein YgaP-like transmembrane
Release factor glutamine methyltransferase N-terminal
Transcriptional regulator AbiEi antitoxin N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Cationic amino acid transporter C-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Por secretion system C-terminal sorting domain
DNA-directed RNA polymerase RpoA/D/Rpb3-type
NADH:flavin oxidoreductase/NADH oxidase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Na+/H+ antiporter MnhB subunit-related protein
DNA replication/recombination mediator RecO N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal