Schiff-base intermediate with substrate; via pyruvic acid
TonB C-terminal domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Putative auto-transporter adhesin head GIN
Bulb-type lectin domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Polysaccharide biosynthesis protein CapD-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Penicillin-binding protein transpeptidase
tRNA pseudouridylate synthase B C-terminal
Outer membrane protein transport protein (OMPP1/FadL/TodX)
Aminoacyl-transfer RNA synthetases class-II family profile
Glycosyl hydrolases family 2 sugar binding
Type IX secretion system protein PorV domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
FAD-dependent oxidoreductase 2 FAD binding
RNA polymerase sigma factor 70 region 4 type 2
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA replication/recombination mediator RecO N-terminal
TonB-dependent receptor-like beta-barrel
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Carboxypeptidase regulatory-like domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Outer membrane protein beta-barrel domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Survival protein SurE-like phosphatase/nucleotidase
DNA mismatch repair proteins mutS family
Phosphoadenosine phosphosulphate reductase
Conserved virulence factor B-like winged helix
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Reversibly protonated during proton transport
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
PBCV-specific basic adaptor domain-containing protein
Glyoxalase/fosfomycin resistance/dioxygenase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Shikimate dehydrogenase substrate binding N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Right-handed parallel beta-helix repeat-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Peptide methionine sulphoxide reductase MsrA
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
NIF system FeS cluster assembly NifU C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Prokaryotic-type class I peptide chain release factors
DNA topoisomerase I catalytic core eukaryotic-type
Signal transduction histidine kinase internal region
Pyridoxamine 5'-phosphate oxidase putative
Carbamoyl-phosphate synthase small subunit N-terminal
Glycosyl hydrolase family 95 N-terminal domain-containing protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Trigger factor ribosome-binding bacterial
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL15/eL18
Could be important to modulate the pK values of the two catalytic cysteine residues
ABC-type uncharacterised transport system
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Butirosin biosynthesis protein H N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Nuclear transport factor 2 family protein
Ribonucleotide reductase large subunit C-terminal
DNA helicase Holliday junction RuvA type
Cysteine sulfenic acid (-SOH) intermediate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Mannose-6-phosphate isomerase type II C-terminal
T9SS C-terminal target domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Protease complex subunit PrcB family protein
Phage terminase large subunit N-terminal
Peptidase M17 leucyl aminopeptidase N-terminal
Thiamin pyrophosphokinase thiamin-binding
Large ribosomal subunit protein uL6 alpha-beta
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Small ribosomal subunit protein uS4 N-terminal
Membrane fusion protein biotin-lipoyl like
Lipocalin-like domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Alpha-D-phosphohexomutase alpha/beta/alpha
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glycosyl transferase family 3 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
General stress protein FMN-binding split barrel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pseudouridine synthase I TruA alpha/beta
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Major facilitator superfamily (MFS) profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
O-(3'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glycine cleavage T-protein C-terminal barrel
Peptidase M43 pregnancy-associated plasma-A
Integral membrane protein YccS N-terminal
Alanyl-transfer RNA synthetases family profile
Quercetin 2,3-dioxygenase C-terminal cupin
Resolvase/invertase-type recombinase catalytic
Urease accessory protein UreH-like transmembrane
Por secretion system C-terminal sorting domain
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Phosphoribosylformylglycinamidine synthase linker
Cationic amino acid transporter C-terminal
Inward rectifier potassium channel C-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Nuclease-associated modular DNA-binding 1
SUF system FeS cluster assembly SufBD N-terminal
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Glycosyl hydrolase family 30 beta sandwich
Thymidylate synthase/dCMP hydroxymethylase
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidase M1 membrane alanine aminopeptidase
Beta-hexosaminidase bacterial type N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphoribosylformylglycinamidine synthase
Anthranilate synthase component I N-terminal
Important for beta-aspartyl-AMP intermediate formation
Polysaccharide chain length determinant N-terminal
Translation elongation factor P/YeiP central
Polymerase/histidinol phosphatase N-terminal
Exonuclease VII large subunit C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Polysaccharide biosynthesis protein C-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Type I restriction enzyme R protein N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Plays an important role in substrate specificity
S-adenosyl-L-homocysteine hydrolase NAD binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Outer membrane lipoprotein carrier protein LolA
Mandelate racemase/muconate lactonizing enzyme C-terminal
Putative beta-lactamase-inhibitor-like PepSY-like
Glucose-methanol-choline oxidoreductase N-terminal
Haem-binding uptake Tiki superfamily ChaN
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA-directed DNA polymerase family A palm
Homogentisate 1,2-dioxygenase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Important for autoinhibition of adenylyltransferase activity
Insecticide toxin TcdB middle/N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RNA binding; important for wobble base 34 recognition
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Organic solvent tolerance-like N-terminal
Carboxypeptidase-like regulatory domain-containing protein
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Transglutaminase-like domain-containing protein
Superoxide dismutase copper/zinc binding
RNA 2-O ribose methyltransferase substrate binding
Contractile injection system tube protein N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycosyl-hydrolase 97 C-terminal oligomerisation
ABC-type glycine betaine transport system substrate-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Histidine-specific methyltransferase SAM-dependent
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-102)
Formamidopyrimidine-DNA glycosylase catalytic
Chromosomal replication initiator DnaA C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Ribose-phosphate pyrophosphokinase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Trimeric autotransporter adhesin YadA-like head
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Bacterial bifunctional deaminase-reductase C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Sodium/calcium exchanger membrane region