Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Antitoxin Xre/MbcA/ParS-like toxin-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Membrane fusion protein biotin-lipoyl like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
DNA replication/recombination mediator RecO N-terminal
Type II secretion system protein GspE N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Bacterial type II secretion system protein E
Reversibly protonated during proton transport
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Heat-inducible transcription repressor HrcA C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Sporulation stage II protein D amidase enhancer LytB N-terminal
PhoD-like phosphatase metallophosphatase
CRISPR-associated protein Cas6 C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Na+-translocating membrane potential-generating system MpsC
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycosyl hydrolase-like 10 domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cytochrome b/b6 N-terminal region profile
Penicillin-binding protein transpeptidase
Prokaryotic-type class I peptide chain release factors
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
May play a role in transmitting local conformational changes
Glucosamine/galactosamine-6-phosphate isomerase
RNA polymerase sigma factor 70 region 4 type 2
Resolvase/invertase-type recombinase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glucose-methanol-choline oxidoreductase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Major facilitator superfamily (MFS) profile
NADH:ubiquinone oxidoreductase 30kDa subunit
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Cation-transporting P-type ATPase N-terminal
Positions MEP for the nucleophilic attack
Anthranilate synthase component I N-terminal
Peptidase M10A and M12B matrixin and adamalysin
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Polysaccharide chain length determinant N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Cation efflux system protein involved in nickel and cobalt tolerance
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Cyanobacterial aminoacyl-tRNA synthetase CAAD
SUF system FeS cluster assembly SufBD N-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Polymerase/histidinol phosphatase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Lysyl-tRNA synthetase N-terminal transmembrane region
Phosphatidylglycerol lysyltransferase C-terminal
Blue (type 1) copper domain-containing protein
Glycine cleavage T-protein C-terminal barrel
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cytochrome b561 bacterial/Ni-hydrogenase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
NIF system FeS cluster assembly NifU N-terminal
Glyoxalase/fosfomycin resistance/dioxygenase
Phosphoribosylformylglycinamidine synthase linker
Polypeptide-transport-associated ShlB-type
Peptidase S9 prolyl oligopeptidase catalytic
TonB-dependent receptor-like beta-barrel
Probable transposase IS891/IS1136/IS1341
Aminoacyl-transfer RNA synthetases class-II family profile
Glycosyl transferase family 28 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycoside hydrolase family 31 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Spore coat protein U domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Gamma-glutamylcyclotransferase AIG2-like
Outer membrane protein beta-barrel domain-containing protein
Photosystem I PsaL reaction centre subunit XI
Inosine/uridine-preferring nucleoside hydrolase
Glycosyl transferase family 3 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
Phosphoadenosine phosphosulphate reductase
Sodium/calcium exchanger membrane region
Schiff-base intermediate with acetaldehyde
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribulose bisphosphate carboxylase small subunit
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Acyl-CoA dehydrogenase/oxidase N-terminal
Interaction with polymerase core subunit RpoC
ATP synthase F1 complex delta/epsilon subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Inward rectifier potassium channel C-terminal
Sodium symporter small subunit predicted
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Mannose-6-phosphate isomerase type II C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Neurotransmitter-gated ion-channel ligand-binding
HicB-like antitoxin of toxin-antitoxin system
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Molybdopterin cofactor biosynthesis C (MoaC)
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Putative regulatory protein FmdB Zinc ribbon
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Increases the nucleophilicity of the active site Cys
Magnesium chelatase subunit H N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alanyl-transfer RNA synthetases family profile
Photosystem II cytochrome b559 N-terminal
Photosystem II cytochrome b559 alpha subunit lumenal region
Na+/H+ antiporter MnhB subunit-related protein
Inosine/uridine-preferring nucleoside hydrolase domain-containing protein
ABC-type glycine betaine transport system substrate-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
BREX system Lon protease-like BrxL N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Superoxide dismutase copper/zinc binding
Cell envelope-related transcriptional attenuator
N,N-dimethylformamidase beta subunit-like C-terminal
Polysaccharide biosynthesis protein C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed DNA polymerase family B multifunctional
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Galactofuranosyltransferase GlfT2 N-terminal
Cytochrome b/b6 C-terminal region profile
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Bacterial Glycosyl hydrolase family 3 C-terminal
P pilus assembly protein, chaperone PapD
Helix-hairpin-helix DNA-binding motif class 1
Translation initiation factor beta propellor-like
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Sugar fermentation stimulation protein C-terminal
Zn-dependent hydrolase of the beta-lactamase fold-like protein
Homocysteine biosynthesis enzyme sulfur-incorporation
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
DNA mismatch repair proteins mutS family
Protein O-mannosyl-transferase C-terminal four TM
Peptidase M1 membrane alanine aminopeptidase
NAD(P) transhydrogenase alpha subunit C-terminal
Essential for prephenate dehydratase activity
Glycoside hydrolase family 57 N-terminal
Plastid lipid-associated protein/fibrillin conserved
Cytochrome C biogenesis protein transmembrane
Pyruvate phosphate dikinase AMP/ATP-binding
ABC transporter substrate-binding protein PnrA-like
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Type I restriction modification DNA specificity
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Moybdenum cofactor oxidoreductase dimerisation
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glycine zipper domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Translation elongation factor P/YeiP central
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL2 C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
DNA primase/polymerase bifunctional N-terminal
6-phosphogluconate dehydrogenase C-terminal
Peptide methionine sulphoxide reductase MsrA
Septum formation inhibitor MinC C-terminal
Putative glycogen debranching enzyme N-terminal
Chromosomal replication initiator DnaA C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NIF system FeS cluster assembly NifU C-terminal
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
Prepilin type IV endopeptidase peptidase
PsbP C-terminal domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Methionyl-tRNA synthetase anticodon-binding
Pseudouridine synthase I TruA alpha/beta
Magnesium-protoporphyrin IX methyltransferase C-terminal
Urease accessory protein UreH-like transmembrane
Large ribosomal subunit protein uL6 alpha-beta
Type IV secretion system coupling protein TraD DNA-binding
Beta-lactamase hydrolase-like protein phosphatase-like
Haem-binding uptake Tiki superfamily ChaN
Photosystem II manganese-stabilizing polypeptide
ABC-type uncharacterised transport system
Proton acceptor; for glutaminase activity
Periplasmic copper-binding protein NosD beta helix
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Schiff-base intermediate with substrate; via pyruvic acid
FAD-dependent oxidoreductase 2 FAD binding
Involved in tetramerization or stability of the tetramer
Photosystem I reaction center subunit III
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Light-independent protochlorophyllide reductase subunit B-like C-terminal
NAD(P)H-quinone oxidoreductase subunit 2 N-terminal
Exonuclease VII large subunit C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Small ribosomal subunit protein uS4 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Arginine decarboxylase C-terminal helical
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-directed DNA polymerase family A palm
Schiff-base intermediate with substrate; via topaquinone
Glycosyltransferase 2-like prokaryotic type
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein uL15/eL18
N6 adenine-specific DNA methyltransferase N-terminal
Heme-copper oxidase subunit III family profile
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal