Major facilitator superfamily (MFS) profile
Peptidase S9 prolyl oligopeptidase catalytic
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Heat-inducible transcription repressor HrcA
Resolvase/invertase-type recombinase catalytic
Glycoside hydrolase family 31 N-terminal
Membrane fusion protein biotin-lipoyl like
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine 5'-phosphosulfate reductase
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Holliday junction branch migration complex subunit RuvA
NAD(P)H-quinone oxidoreductase subunit H 2
Glycosyltransferase subfamily 4-like N-terminal
RNA polymerase sigma factor 70 region 4 type 2
NAD(P)H-quinone oxidoreductase subunit K 1
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Photosystem I reaction center subunit XII
PhoD-like phosphatase metallophosphatase
Cytochrome b/b6 C-terminal region profile
3-isopropylmalate dehydratase large subunit
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Fatty acid synthase subunit PfaD N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Pyrroline-5-carboxylate reductase catalytic N-terminal
Contractile injection system tube protein N-terminal
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Homocysteine biosynthesis enzyme sulfur-incorporation
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Ribosomal RNA large subunit methyltransferase H
Sulfate/thiosulfate import ATP-binding protein CysA
RND efflux pump membrane fusion protein barrel-sandwich
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Polysaccharide biosynthesis protein C-terminal
NAD(P)H-quinone oxidoreductase subunit 2
Prokaryotic-type class I peptide chain release factors
Holliday junction branch migration complex subunit RuvB
NIF system FeS cluster assembly NifU C-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Glycosyl transferase family 28 C-terminal
Potassium-transporting ATPase KdpC subunit
TonB-dependent receptor-like beta-barrel
NAD(P)H-quinone oxidoreductase subunit N
Bifunctional pantoate ligase/cytidylate kinase
UDP-3-O-acylglucosamine N-acyltransferase 1
NAD(P)H-quinone oxidoreductase subunit O
Bacterial type II secretion system protein E
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Phosphoribosylformylglycinamidine cyclo-ligase
Phosphate import ATP-binding protein PstB 2
Electron transfer via tryptophanyl radical
6-hydroxymethylpterin diphosphokinase MptE-like
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Glutamyl-tRNA(Gln) amidotransferase subunit A
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Involved in ionization of N3 of dUMP, leading to its activation
Cytochrome b6-f complex iron-sulfur subunit
Putative 8-amino-7-oxononanoate synthase
RNA 2-O ribose methyltransferase substrate binding
NAD(P)H-quinone oxidoreductase subunit 1
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-246)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-97)
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Light-independent protochlorophyllide reductase subunit N
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
ATP phosphoribosyltransferase regulatory subunit
Light-independent protochlorophyllide reductase subunit B
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Magnesium chelatase subunit H N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
NAD(P)H-quinone oxidoreductase subunit I
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
Sec-independent protein translocase protein TatA
Decreases cation selectivity. Decreases the binding affinity of TEA and TBA. Nearly abolishes block by Cd(2+).
Displays an increased sensitivity to propofol but not to desflurane.
Increases the binding affinity of TBA. Weakens block by Cd(2+).
Marked gain of function, with a ten-fold shift of the proton dose-response curve towards lower concentrations.
Marked gain of function, with a ten-fold shift of the proton dose-response curve towards lower concentrations. Shows also slower apparent rate constants for activation and deactivation. Displays an increased sensitivity to propofol but a decreased sensitivity to desflurane.
Putative membrane protein insertion efficiency factor
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase
NAD(P)H-quinone oxidoreductase subunit M
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Phosphoribosylformylglycinamidine synthase subunit PurQ
Alanyl-transfer RNA synthetases family profile
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Acetylserotonin O-methyltransferase dimerisation
Ribosomal RNA small subunit methyltransferase H
tRNA N6-adenosine threonylcarbamoyltransferase
Antitoxin Xre/MbcA/ParS-like toxin-binding
ATP-dependent Clp protease proteolytic subunit 1
N-(5'-phosphoribosyl)anthranilate isomerase
DNA-directed DNA polymerase family A palm
Probable dual-specificity RNA methyltransferase RlmN
Polymerase/histidinol phosphatase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycine cleavage T-protein C-terminal barrel
NAD(P)H-quinone oxidoreductase subunit K 2
Glycosyltransferase family 28 N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Photosystem II reaction center protein I
6-phosphogluconate dehydrogenase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Probable transcriptional regulatory protein glr2507
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Bacterial bifunctional deaminase-reductase C-terminal
Glycosyl transferase family 3 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Reversibly protonated during proton transport
Ribosomal protein uS12 methylthiotransferase RimO
Tryptophan synthase beta chain-like PALP
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Photosystem I reaction center subunit IV
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Ribosomal RNA small subunit methyltransferase G
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Photosystem I P700 chlorophyll a apoprotein A2
ATP-dependent dethiobiotin synthetase BioD
4-hydroxy-tetrahydrodipicolinate reductase
Quercetin 2,3-dioxygenase C-terminal cupin
Photosystem I reaction center subunit XI
DNA-directed RNA polymerase subunit gamma
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Polyribonucleotide nucleotidyltransferase
Proton acceptor; for glutaminase activity
Plastid lipid-associated protein/fibrillin conserved
Anthranilate synthase component I N-terminal
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin)
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
3-phosphoshikimate 1-carboxyvinyltransferase
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Plays an important role in substrate specificity
Probable 2-phosphosulfolactate phosphatase
Pyruvate phosphate dikinase AMP/ATP-binding
NAD(P)H-quinone oxidoreductase subunit J
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
UDP-3-O-acylglucosamine N-acyltransferase 3
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphoribosylformylglycinamidine synthase subunit PurL
Imidazole glycerol phosphate synthase subunit HisF
Methionyl-tRNA synthetase anticodon-binding
Cell envelope-related transcriptional attenuator
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Photosystem I reaction center subunit III
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Membrane insertase YidC/Oxa/ALB C-terminal
Transcription antitermination protein NusB
Schiff-base intermediate with acetaldehyde
NADPH-dependent 7-cyano-7-deazaguanine reductase
Phycoerythrobilin:ferredoxin oxidoreductase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
UDP-3-O-acylglucosamine N-acyltransferase 2
Transcriptional regulator AbiEi antitoxin N-terminal
N-acetyl-gamma-glutamyl-phosphate reductase
Involved in Mg(2+) ion dislocation from EF-Tu
Photosystem II reaction center protein L
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Protein-L-isoaspartate O-methyltransferase
Putative 3-methyladenine DNA glycosylase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Photosystem II reaction center protein K
Ribulose bisphosphate carboxylase small subunit
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Penicillin-binding protein transpeptidase
Leucyl/phenylalanyl-tRNA--protein transferase
Probable transposase IS891/IS1136/IS1341
Putative auto-transporter adhesin head GIN
Type IV secretion system coupling protein TraD DNA-binding
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
NADH:ubiquinone oxidoreductase 30kDa subunit
Nitrite/Sulfite reductase ferredoxin-like
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Polysaccharide chain length determinant N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ADP-dependent (S)-NAD(P)H-hydrate dehydratase
Bifunctional NAD(P)H-hydrate repair enzyme Nnr
Large ribosomal subunit protein bL12 C-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cell division topological specificity factor
Superoxide dismutase copper/zinc binding
DNA-directed RNA polymerase subunit omega
Gp5/Type VI secretion system Vgr protein OB-fold
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA-directed RNA polymerase subunit alpha
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
NIF system FeS cluster assembly NifU N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
NAD(P)H-quinone oxidoreductase subunit 3
ATP-dependent Clp protease adapter protein ClpS
Photosystem I reaction center subunit II
Probable nicotinate-nucleotide adenylyltransferase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
NAD(P)H-quinone oxidoreductase subunit H 1
Signal transduction histidine kinase dimerisation/phosphoacceptor
Cytochrome C biogenesis protein transmembrane
Photosystem II reaction center protein H
Prepilin type IV endopeptidase peptidase
Putative pterin-4-alpha-carbinolamine dehydratase 1
Photosystem II assembly lipoprotein Ycf48
Phenylalanine--tRNA ligase alpha subunit
Schiff-base intermediate with substrate; via pyruvic acid
ATP-dependent Clp protease ATP-binding subunit ClpX
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Heme-copper oxidase subunit III family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Putative pterin-4-alpha-carbinolamine dehydratase 2
Photosystem II reaction center protein X
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
Ribosomal RNA small subunit methyltransferase A
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Release factor glutamine methyltransferase
Peptidase M1 membrane alanine aminopeptidase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Chromosomal replication initiator protein DnaA
Inosine/uridine-preferring nucleoside hydrolase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Probable septum site-determining protein MinC
Glutamate-1-semialdehyde 2,1-aminomutase
Putative ABC transporter ATP-binding protein gll0289
SUF system FeS cluster assembly SufBD N-terminal
Potassium-transporting ATPase potassium-binding subunit
UDP-N-acetylenolpyruvoylglucosamine reductase
Ribulose bisphosphate carboxylase large chain
RNA binding; important for wobble base 34 recognition
Increases nucleophilicity of active site Cys
Carbamoyl-phosphate synthase small subunit N-terminal
ATP-dependent Clp protease proteolytic subunit 2
Shikimate dehydrogenase substrate binding N-terminal
Sugar fermentation stimulation protein homolog
Uncharacterized RNA methyltransferase gll3134
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
Photosystem I P700 chlorophyll a apoprotein A1
DNA-directed RNA polymerase subunit beta'
N-acetylmuramic acid 6-phosphate etherase
Peptidase M43 pregnancy-associated plasma-A
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Solute-binding protein family 3/N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase
1-deoxy-D-xylulose 5-phosphate reductoisomerase
DNA mismatch repair proteins mutS family
Involved in tetramerization or stability of the tetramer