RNA 2-O ribose methyltransferase substrate binding
Ribose-phosphate pyrophosphokinase N-terminal
Flagellar Assembly Protein A N-terminal region
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
N(4)-bis(aminopropyl)spermidine synthase C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Schiff-base intermediate with acetaldehyde
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar basal body rod protein N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Putative oxidoreductase/dehydrogenase Rossmann-like
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Flagellar basal-body/hook protein C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Aspartate/homoserine dehydrogenase NAD-binding
DNA-directed DNA polymerase family A palm
Helix-hairpin-helix DNA-binding motif class 1
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyruvate phosphate dikinase AMP/ATP-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Thiamine pyrophosphate enzyme TPP-binding
Resolvase/invertase-type recombinase catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Cation-transporting P-type ATPase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
RNA binding; important for wobble base 34 recognition
Important for interaction with partner proteins
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Major facilitator superfamily (MFS) profile
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
ABC-type uncharacterised transport system
Aconitase A/isopropylmalate dehydratase small subunit swivel
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cell envelope-related transcriptional attenuator
Glycosyl transferase family 3 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Reversibly protonated during proton transport
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Chromosomal replication initiator DnaA C-terminal
6-phosphogluconate dehydrogenase C-terminal
Thiamin pyrophosphokinase thiamin-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase M1 membrane alanine aminopeptidase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Important for beta-aspartyl-AMP intermediate formation
Schiff-base intermediate with substrate; via pyruvic acid
Pseudouridine synthase I TruA alpha/beta
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
DNA polymerase III delta subunit C-terminal
Formylmethanofuran dehydrogenase subunit E
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Polysaccharide biosynthesis protein C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Acetylserotonin O-methyltransferase dimerisation
Polymerase/histidinol phosphatase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Polysaccharide biosynthesis protein CapD-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Release factor glutamine methyltransferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
YbaK/aminoacyl-tRNA synthetase-associated
Bacterial type II secretion system protein E
Sporulation stage IV protein A C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Conserved hypothetical protein CHP02679 N terminus
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Sporulation transcription regulator WhiA N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Manganese/iron superoxide dismutase C-terminal
Translation elongation factor SelB winged helix type 3
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
DNA mismatch repair proteins mutS family
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Membrane insertase YidC/Oxa/ALB C-terminal
DNA replication/recombination mediator RecO N-terminal
ABC transporter substrate-binding protein PnrA-like
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Prepilin type IV endopeptidase peptidase
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Interaction with polymerase core subunit RpoC
Transcription factor NikR nickel binding C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Flagellar hook-length control protein-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
NIF system FeS cluster assembly NifU C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Phosphotransferase system enzyme I N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Proton acceptor; for glutaminase activity
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar assembly protein FliH/Type III secretion system HrpE
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Phosphomannose isomerase type I catalytic
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NIF system FeS cluster assembly NifU N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Anthranilate synthase component I N-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Prokaryotic-type class I peptide chain release factors
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation elongation factor P/YeiP central
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Polysaccharide chain length determinant N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
O-(5'-phospho-DNA)-tyrosine intermediate
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Phosphodiester glycosidase domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Magnesium transporter MgtE intracellular
Glutamate synthase alpha subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein uL15/eL18
Exonuclease VII large subunit C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Tryptophan synthase beta chain-like PALP
Na+-translocating membrane potential-generating system MpsC
Restriction endonuclease type II DpnII-like
NADH:ubiquinone oxidoreductase 30kDa subunit
Small ribosomal subunit protein uS4 N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Type III secretion system flagellar brake protein YcgR PilZN
Shikimate dehydrogenase substrate binding N-terminal
Phosphoribosylformylglycinamidine synthase linker
Lysidine-tRNA(Ile) synthetase C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Methylene-tetrahydrofolate reductase C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Schiff-base intermediate with D-ribose 5-phosphate
Molybdopterin cofactor biosynthesis C (MoaC)
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Alanyl-transfer RNA synthetases family profile
6-phosphogluconate dehydrogenase NADP-binding
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic