Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Solute-binding protein family 3/N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
NADH:flavin oxidoreductase/NADH oxidase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Polymerase/histidinol phosphatase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Bacterial type II secretion system protein E
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphocysteine intermediate; for EIIB activity
Flagellar Assembly Protein A N-terminal region
Membrane fusion protein biotin-lipoyl like
Cytochrome C biogenesis protein transmembrane
Gp5/Type VI secretion system Vgr protein OB-fold
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Sporulation stage IV protein A C-terminal
Cation-transporting P-type ATPase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar motor switch protein FliN-like C-terminal
Bacterial transcription activator effector binding
Schiff-base intermediate with acetaldehyde
Carbamoyl-phosphate synthase small subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RND efflux pump membrane fusion protein barrel-sandwich
Tryptophan synthase beta chain-like PALP
YbaK/aminoacyl-tRNA synthetase-associated
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Alpha-D-phosphohexomutase alpha/beta/alpha
Membrane insertase YidC/Oxa/ALB C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Major facilitator superfamily (MFS) profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Ionotropic glutamate receptor C-terminal
Na+-translocating membrane potential-generating system MpsC
Penicillin-binding protein transpeptidase
Glucosamine/galactosamine-6-phosphate isomerase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyruvate phosphate dikinase AMP/ATP-binding
Cysteine sulfenic acid (-SOH) intermediate
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Damage-control phosphatase ARMT1-like metal-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Polysaccharide biosynthesis protein C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Threonine/serine exporter-like N-terminal
Alanyl-transfer RNA synthetases family profile
Type III secretion system flagellar brake protein YcgR PilZN
Large ribosomal subunit protein uL6 alpha-beta
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Putative aromatic acid exporter C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Schiff-base intermediate with dihydroxyacetone-P
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Exonuclease VII large subunit C-terminal
DNA-directed DNA polymerase family A palm
DNA mismatch repair proteins mutS family
Small ribosomal subunit protein uS4 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Dinitrogenase iron-molybdenum cofactor biosynthesis
Involved in allosteric activation by GTP
Molybdopterin cofactor biosynthesis C (MoaC)
Translation elongation factor P/YeiP central
Sugar fermentation stimulation protein C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Gfo/Idh/MocA-like oxidoreductase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphoribosylformylglycinamidine synthase linker
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Essential for prephenate dehydratase activity
ABC-type glycine betaine transport system substrate-binding
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
S-adenosylmethionine-dependent methyltransferase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein uL15/eL18
Plays an important role in substrate specificity
Phosphotransferase system enzyme I N-terminal
Polysaccharide chain length determinant N-terminal
Proton acceptor; for glutaminase activity
ABC transporter substrate-binding protein PnrA-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Cell envelope-related transcriptional attenuator
Gfo/Idh/MocA-like oxidoreductase C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Signal transduction histidine kinase internal region
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Release factor glutamine methyltransferase N-terminal
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Important for substrate specificity; cannot use PPi as phosphoryl donor
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Chromosomal replication initiator DnaA C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycoside hydrolase family 31 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Resolvase/invertase-type recombinase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribosomal RNA adenine methylase transferase N-terminal
Septum formation inhibitor MinC C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Reversibly protonated during proton transport
MmyB-like transcription regulator ligand binding
Glycosyl hydrolase family 30 beta sandwich
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Mannose-6-phosphate isomerase type II C-terminal
Prepilin type IV endopeptidase peptidase
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 3
RNA binding; important for wobble base 34 recognition
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glycoside hydrolase family 42 N-terminal
Flagellar hook-length control protein-like C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
5-glutamyl coenzyme A thioester intermediate
RNA 2-O ribose methyltransferase substrate binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Thymidylate synthase/dCMP hydroxymethylase
Positions MEP for the nucleophilic attack
Schiff-base intermediate with acetoacetate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Schiff-base intermediate with D-ribose 5-phosphate
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Saccharopine dehydrogenase-like C-terminal
Glycosyltransferase family 28 N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Plays an important role in discriminating NADH against NADPH
D-galactose/methyl-galactoside binding periplasmic protein MglB
Schiff-base intermediate with substrate; via pyruvic acid
Sporulation stage II protein D amidase enhancer LytB N-terminal
4-hydroxyphenylacetate decarboxylase small gamma subunit C-terminal
4-hydroxyphenylacetate decarboxylase small gamma subunit N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Major facilitator superfamily associated
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Glutathionylspermidine synthase pre-ATP-grasp-like
6-hydroxymethylpterin diphosphokinase MptE-like
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Fatty acid kinase subunit A-like C-terminal
Prokaryotic-type class I peptide chain release factors
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL2 C-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Helix-turn-helix conjugative transposon-like
DNA replication/recombination mediator RecO N-terminal
Phosphotransferase system EIIB component type 2/3
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Interaction with polymerase core subunit RpoC
Helix-hairpin-helix DNA-binding motif class 1
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Ribonucleotide reductase large subunit C-terminal
Pseudouridine synthase I TruA alpha/beta
6-phosphogluconate dehydrogenase C-terminal
Tellurite resistance methyltransferase TehB-like
Thiamin pyrophosphokinase thiamin-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Ribonucleotide reductase large subunit N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
DNA polymerase III delta subunit C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Transcription regulator AsnC/Lrp ligand binding
Phosphoadenosine phosphosulphate reductase
Sodium/calcium exchanger membrane region
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Could be important to modulate the pK values of the two catalytic cysteine residues
Survival protein SurE-like phosphatase/nucleotidase
Phosphomannose isomerase type I catalytic
Gly-cisPro motif, important for rejection of L-amino acids
Choloylglycine hydrolase/NAAA C-terminal
Urease accessory protein UreH-like transmembrane
Tyrosine specific protein phosphatases domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal