Pyridoxamine 5'-phosphate oxidase putative
Proton acceptor; for glutaminase activity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Integral membrane protein YccS N-terminal
Exonuclease VII large subunit C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Phosphotransferase system enzyme I N-terminal
Cytochrome b/b6 N-terminal region profile
Glucose-methanol-choline oxidoreductase N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Solute-binding protein family 3/N-terminal
Transposase IS116/IS110/IS902 C-terminal
Putative regulatory protein FmdB Zinc ribbon
PhoD-like phosphatase metallophosphatase
Tryptophan synthase beta chain-like PALP
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Major facilitator superfamily (MFS) profile
Cytochrome oxidase subunit II copper A binding
4'-phosphopantetheinyl transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptidoglycan recognition protein family
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sporulation transcription regulator WhiA N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
DNA primase/polymerase bifunctional N-terminal
Phosphomannose isomerase type I catalytic
Gram-positive cocci surface proteins LPxTG
Involved in allosteric activation by GTP
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
Cytochrome b561 bacterial/Ni-hydrogenase
Schiff-base intermediate with substrate; via pyruvic acid
Penicillin-binding protein transpeptidase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyruvate phosphate dikinase AMP/ATP-binding
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Glycosyltransferase subfamily 4-like N-terminal
Essential for prephenate dehydratase activity
Gamma-glutamylcyclotransferase AIG2-like
Twin-arginine translocation signal domain-containing protein
Glycosyl transferase family 3 N-terminal
Prokaryotic-type class I peptide chain release factors
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RNA 2-O ribose methyltransferase substrate binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL15/eL18
Cytochrome bc1 complex cytochrome c subunit
Endoribonuclease L-PSP/chorismate mutase-like
Right handed beta helix domain-containing protein
Phosphocysteine intermediate; for EIIB activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Prepilin type IV endopeptidase peptidase
Protein O-mannosyl-transferase C-terminal four TM
Phosphatidic acid phosphatase type 2/haloperoxidase
Schiff-base intermediate with substrate; via topaquinone
Polymerase/histidinol phosphatase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Anthranilate synthase component I N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aminoacyl-transfer RNA synthetases class-II family profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
DNA replication/recombination mediator RecO N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Helix-hairpin-helix DNA-binding motif class 1
DnaJ homologue subfamily C member 28 conserved
Tetracyclin repressor-like C-terminal group 31
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Peptide methionine sulphoxide reductase MsrA
Release factor glutamine methyltransferase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Heme-copper oxidase subunit III family profile
Membrane insertase YidC/Oxa/ALB C-terminal
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycine cleavage T-protein C-terminal barrel
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
ABC-type glycine betaine transport system substrate-binding
NIF system FeS cluster assembly NifU N-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Bacterial type II secretion system protein E
LPXTG cell wall anchor domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cytochrome C biogenesis protein transmembrane
Contractile injection system tube protein N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Plays an important role in substrate specificity
Adaptive response protein AidB N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Threonine/serine exporter-like N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
S-adenosyl-L-homocysteine hydrolase NAD binding
Lactate utilization protein B C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Putative oxidoreductase/dehydrogenase Rossmann-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL6 alpha-beta
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Bacterial bifunctional deaminase-reductase C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
CobB/CobQ-like glutamine amidotransferase
Large ribosomal subunit protein uL2 C-terminal
Probable subtilase-type protease inhibitor
Nuclear transport factor 2 family protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Sodium/calcium exchanger membrane region
Putative Flp pilus-assembly TadG-like N-terminal
Transition state stabilizer; via amide nitrogen
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Beta-hexosaminidase bacterial type N-terminal
Positions MEP for the nucleophilic attack
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Important for substrate specificity; cannot use PPi as phosphoryl donor
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH:ubiquinone oxidoreductase 30kDa subunit
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
N-acetylneuraminic acid synthase N-terminal
MmyB-like transcription regulator ligand binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Removed in mature form; by autocatalysis
Reversibly protonated during proton transport
Gly-cisPro motif, important for rejection of L-amino acids
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Translation elongation factor P/YeiP central
Pyridoxamine kinase/Phosphomethylpyrimidine kinase