S-adenosyl-L-homocysteine hydrolase NAD binding
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Thiamine pyrophosphate enzyme TPP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-236); in linked form
Interchain (with Cys-48); in linked form
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Damage-control phosphatase ARMT1-like metal-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Tryptophan synthase beta chain-like PALP
Polymerase/histidinol phosphatase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Gamma-glutamylcyclotransferase AIG2-like
Aspartate/homoserine dehydrogenase NAD-binding
Glycoside hydrolase family 57 N-terminal
RNA 3'-terminal phosphate cyclase insert
Transcription factor NikR nickel binding C-terminal
N-acetylneuraminic acid synthase N-terminal
Large ribosomal subunit protein uL15/eL18
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Probable transposase IS891/IS1136/IS1341
Bacterial transcription activator effector binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Major facilitator superfamily (MFS) profile
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyl transferase family 28 C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial bifunctional deaminase-reductase C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Glucose-6-phosphate isomerase prokaryote
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Bacterial type II secretion system protein E
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Schiff-base intermediate with substrate; via pyruvic acid
O-(5'-phospho-DNA)-tyrosine intermediate
tRNA nucleotidyltransferase substrate binding
Glycerophosphoryl diester phosphodiesterase membrane
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
DNA-directed RNA polymerase subunit 2 hybrid-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Small ribosomal subunit protein uS15 N-terminal
Sodium/calcium exchanger membrane region
Transcription factor CBF/NF-Y/archaeal histone
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Prepilin type IV endopeptidase peptidase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-92)
Formylmethanofuran dehydrogenase subunit E
Tetrahydromethanopterin S-methyltransferase F subunit
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA polymerase II large subunit DP2 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
N6 adenine-specific DNA methyltransferase N-terminal
DNA polymerase alpha/delta/epsilon subunit B
SAM-dependent methyltransferase TRM5/TYW2-type
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Translation elongation factor IF5A C-terminal
Type I restriction modification DNA specificity
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Siroheme decarboxylase AsnC-like ligand binding
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL6 alpha-beta
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Plays an important role in substrate specificity
Thymidylate synthase/dCMP hydroxymethylase
Dinitrogenase iron-molybdenum cofactor biosynthesis
Exonuclease VII large subunit C-terminal
ABC-type glycine betaine transport system substrate-binding
ATPsynthase alpha/beta subunit N-terminal extension
Methanogenesis regulatory protein FilR1 middle
Alanyl-transfer RNA synthetases family profile
Archaeal glycosylation protein B peripheral
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Periplasmic copper-binding protein NosD beta helix
Pyridoxamine 5'-phosphate oxidase putative
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Pseudouridine synthase I TruA alpha/beta
DNA-directed DNA polymerase family B mitochondria/virus
Pyruvate/ketoisovalerate oxidoreductase catalytic
DNA mismatch repair proteins mutS family
DNA-directed RNA polymerase RBP11-like dimerisation
HicB-like antitoxin of toxin-antitoxin system
Methylene-tetrahydrofolate reductase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Large ribosomal subunit protein uL10-like insertion
Pyrimidine nucleoside phosphorylase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NADH:ubiquinone oxidoreductase 30kDa subunit
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Small ribosomal subunit protein uS4 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Inner membrane protein YgaP-like transmembrane
Removed in mature form; by autocatalysis
Succinate dehydogenase/fumarate reductase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cytochrome C biogenesis protein transmembrane
6-hydroxymethylpterin diphosphokinase MptE-like
Helix-hairpin-helix DNA-binding motif class 1
Small zinc finger protein HVO-2753-like zinc-binding pocket
Large ribosomal subunit protein uL2 C-terminal
Polysaccharide biosynthesis protein C-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Signal recognition particle SRP54 helical bundle
Dihydroneopterin aldolase MtpD C-terminal
Glutamate synthase alpha subunit C-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Spo11/DNA topoisomerase VI subunit A N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribose-phosphate pyrophosphokinase N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycogen debranching enzyme bacterial and archaeal type N-terminal
RNA polymerase subunit H/Rpb5 C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Serine/threonine specific protein phosphatases
Interchain (with Cys-220); in linked form
Interchain (with Cys-52); in linked form
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Histidine-specific methyltransferase SAM-dependent
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyrroline-5-carboxylate reductase dimerisation